ENSG00000140553

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000418476 ENSG00000140553 No_inf pgKDN_inf UNC45A protein_coding protein_coding 24.77293 26.78592 23.54973 3.069088 1.984748 -0.1856904 14.880867 7.827327 18.8193120 3.1301566 0.8372043 1.264547 0.61550000 0.284100 0.808775 0.524675 0.002093506 0.002093506 FALSE TRUE
ENST00000471780 ENSG00000140553 No_inf pgKDN_inf UNC45A protein_coding retained_intron 24.77293 26.78592 23.54973 3.069088 1.984748 -0.1856904 2.200115 4.115039 1.0058002 0.8237706 0.4604196 -2.021791 0.08350833 0.149400 0.041500 -0.107900 0.163697719 0.002093506 FALSE TRUE
MSTRG.10198.12 ENSG00000140553 No_inf pgKDN_inf UNC45A protein_coding   24.77293 26.78592 23.54973 3.069088 1.984748 -0.1856904 1.947825 5.019593 0.2649090 2.5780667 0.2649090 -4.193416 0.07951667 0.204950 0.011725 -0.193225 0.339524139 0.002093506 FALSE TRUE
MSTRG.10198.14 ENSG00000140553 No_inf pgKDN_inf UNC45A protein_coding   24.77293 26.78592 23.54973 3.069088 1.984748 -0.1856904 1.921292 3.442692 0.2749601 1.1754233 0.1914012 -3.598890 0.08158333 0.146275 0.011600 -0.134675 0.354653458 0.002093506 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000140553 E001 0.0000000       15 90930180 90930217 38 +      
ENSG00000140553 E002 0.0000000       15 90930218 90930255 38 +      
ENSG00000140553 E003 0.0000000       15 90930953 90931052 100 +      
ENSG00000140553 E004 0.0000000       15 90931053 90931579 527 +      
ENSG00000140553 E005 0.0000000       15 90933977 90934040 64 +      
ENSG00000140553 E006 0.0000000       15 90934041 90934143 103 +      
ENSG00000140553 E007 0.0000000       15 90934339 90934434 96 +      
ENSG00000140553 E008 0.0000000       15 90934435 90934549 115 +      
ENSG00000140553 E009 0.0000000       15 90934944 90935100 157 +      
ENSG00000140553 E010 0.1268540 0.0123162970 5.698581e-01   15 90935101 90935284 184 + 0.000 0.093 9.506
ENSG00000140553 E011 1.6165516 0.0102608303 1.989618e-01 4.804695e-01 15 90935285 90935309 25 + 0.302 0.498 1.095
ENSG00000140553 E012 2.4789398 0.0666035525 2.931859e-01 5.867634e-01 15 90935310 90935330 21 + 0.441 0.613 0.818
ENSG00000140553 E013 1.4549187 0.0113640262 2.133042e-01 4.985202e-01 15 90935331 90935375 45 + 0.479 0.291 -1.075
ENSG00000140553 E014 0.0000000       15 90935424 90935543 120 +      
ENSG00000140553 E015 9.2560596 0.0371300511 1.694538e-01 4.413424e-01 15 90935544 90935705 162 + 1.090 0.924 -0.613
ENSG00000140553 E016 6.1489194 0.0023437285 1.573917e-03 2.122431e-02 15 90935946 90935982 37 + 1.002 0.661 -1.338
ENSG00000140553 E017 0.1272623 0.0123486406 5.698504e-01   15 90935983 90936136 154 + 0.000 0.093 11.807
ENSG00000140553 E018 0.6104390 0.6138772638 8.366458e-01 9.414687e-01 15 90936137 90936284 148 + 0.244 0.169 -0.661
ENSG00000140553 E019 16.8440718 0.0008728401 1.733955e-01 4.466693e-01 15 90936285 90936460 176 + 1.298 1.205 -0.326
ENSG00000140553 E020 11.5976722 0.0018661438 2.327617e-01 5.214226e-01 15 90939731 90939823 93 + 1.148 1.051 -0.349
ENSG00000140553 E021 16.0096799 0.0017295957 4.508952e-01 7.240905e-01 15 90940306 90940473 168 + 1.257 1.205 -0.185
ENSG00000140553 E022 1.0899405 0.0107436745 2.795692e-01 5.728149e-01 15 90940474 90940976 503 + 0.399 0.234 -1.075
ENSG00000140553 E023 5.5190601 0.0032365717 7.994871e-01 9.247852e-01 15 90942437 90942442 6 + 0.798 0.828 0.118
ENSG00000140553 E024 13.4894974 0.0011683104 7.824029e-01 9.162747e-01 15 90942443 90942605 163 + 1.148 1.171 0.083
ENSG00000140553 E025 5.4117354 0.0029200188 2.702250e-07 1.426058e-05 15 90942606 90942911 306 + 0.353 1.003 2.851
ENSG00000140553 E026 18.2677218 0.0199172087 8.977402e-01 9.662566e-01 15 90942912 90943082 171 + 1.275 1.292 0.061
ENSG00000140553 E027 0.0000000       15 90943083 90943089 7 +      
ENSG00000140553 E028 19.8929482 0.0090459213 6.208213e-01 8.361436e-01 15 90944892 90945035 144 + 1.298 1.337 0.139
ENSG00000140553 E029 9.5533125 0.0015243345 8.051079e-01 9.278607e-01 15 90945036 90945063 28 + 1.033 1.013 -0.075
ENSG00000140553 E030 11.2304100 0.0219062172 2.695938e-01 5.632708e-01 15 90946614 90946683 70 + 1.140 1.033 -0.390
ENSG00000140553 E031 13.7041276 0.0059511650 5.212358e-01 7.753053e-01 15 90946684 90946764 81 + 1.192 1.142 -0.178
ENSG00000140553 E032 22.4300737 0.0020721687 7.599174e-01 9.059146e-01 15 90946765 90946914 150 + 1.378 1.361 -0.059
ENSG00000140553 E033 0.3807797 0.0236629834 1.158329e-01   15 90946915 90947138 224 + 0.000 0.234 13.260
ENSG00000140553 E034 0.7445014 0.0315751044 4.599665e-01 7.315173e-01 15 90947237 90947795 559 + 0.177 0.291 0.925
ENSG00000140553 E035 17.1238508 0.0050024665 1.268438e-01 3.775286e-01 15 90947796 90947890 95 + 1.192 1.308 0.407
ENSG00000140553 E036 24.3676250 0.0006109836 6.366838e-01 8.448856e-01 15 90948142 90948283 142 + 1.417 1.391 -0.089
ENSG00000140553 E037 3.3570578 0.0951830308 1.484546e-01 4.103289e-01 15 90948284 90948653 370 + 0.478 0.743 1.174
ENSG00000140553 E038 25.6920495 0.0005415045 4.039480e-01 6.867957e-01 15 90948654 90948794 141 + 1.449 1.404 -0.157
ENSG00000140553 E039 14.5767586 0.0009790687 8.287901e-01 9.380896e-01 15 90949316 90949352 37 + 1.199 1.185 -0.051
ENSG00000140553 E040 17.0731331 0.0011204996 6.635777e-01 8.599948e-01 15 90949353 90949443 91 + 1.239 1.271 0.112
ENSG00000140553 E041 17.8250335 0.0008095622 4.553421e-01 7.278625e-01 15 90949654 90949720 67 + 1.245 1.298 0.185
ENSG00000140553 E042 3.6469672 0.0183553476 1.655612e-04 3.584655e-03 15 90949721 90950153 433 + 0.302 0.843 2.569
ENSG00000140553 E043 21.5827529 0.0009017255 9.419449e-01 9.836326e-01 15 90950154 90950267 114 + 1.354 1.352 -0.009
ENSG00000140553 E044 12.4378349 0.0158430236 2.774919e-01 5.707516e-01 15 90950500 90950615 116 + 1.178 1.078 -0.359
ENSG00000140553 E045 0.0000000       15 90952929 90953046 118 +      
ENSG00000140553 E046 13.5651530 0.0011735514 3.382087e-01 6.300409e-01 15 90953155 90953310 156 + 1.199 1.127 -0.257
ENSG00000140553 E047 85.0661776 0.0002061800 2.514159e-01 5.425781e-01 15 90953459 90954093 635 + 1.915 1.951 0.121

Help

Please Click HERE to learn more details about the results from DEXseq.