ENSG00000140575

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000268182 ENSG00000140575 No_inf pgKDN_inf IQGAP1 protein_coding protein_coding 160.5295 101.3813 186.169 5.688778 7.925976 0.8767563 43.68205 18.80876 54.24432 0.3022123 0.6052267 1.5275665 0.2598750 0.18745 0.292975 0.105525 0.04586142 0.04586142 FALSE TRUE
ENST00000559674 ENSG00000140575 No_inf pgKDN_inf IQGAP1 protein_coding retained_intron 160.5295 101.3813 186.169 5.688778 7.925976 0.8767563 24.62698 13.57420 25.57347 5.1901219 6.6300968 0.9132820 0.1468500 0.12810 0.133900 0.005800 0.90918636 0.04586142 FALSE FALSE
ENST00000560738 ENSG00000140575 No_inf pgKDN_inf IQGAP1 protein_coding protein_coding 160.5295 101.3813 186.169 5.688778 7.925976 0.8767563 51.88216 30.30634 66.07440 0.7167952 1.4071536 1.1242140 0.3218583 0.30235 0.357375 0.055025 0.66741103 0.04586142 FALSE TRUE
ENST00000561086 ENSG00000140575 No_inf pgKDN_inf IQGAP1 protein_coding retained_intron 160.5295 101.3813 186.169 5.688778 7.925976 0.8767563 33.64591 30.90623 37.09580 1.8576163 2.3834539 0.2632801 0.2248667 0.30610 0.198950 -0.107150 0.05046175 0.04586142 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000140575 E001 0.4814789 1.533214e-02 7.470306e-01   15 90388242 90388246 5 + 0.183 0.128 -0.607
ENSG00000140575 E002 1.0820080 1.332634e-02 4.565915e-01 7.288741e-01 15 90388247 90388260 14 + 0.347 0.227 -0.830
ENSG00000140575 E003 2.1542296 6.572864e-03 1.088509e-01 3.463428e-01 15 90388261 90388276 16 + 0.558 0.308 -1.344
ENSG00000140575 E004 8.6410935 1.863300e-03 3.529213e-02 1.798212e-01 15 90388277 90388354 78 + 1.032 0.813 -0.830
ENSG00000140575 E005 8.9304284 1.867191e-03 4.733215e-01 7.403499e-01 15 90388355 90388396 42 + 1.003 0.932 -0.263
ENSG00000140575 E006 10.7400918 1.268847e-03 5.057641e-01 7.645789e-01 15 90390774 90390824 51 + 1.072 1.012 -0.222
ENSG00000140575 E007 13.9269029 1.092647e-03 2.702774e-02 1.527522e-01 15 90390825 90390873 49 + 1.213 1.026 -0.674
ENSG00000140575 E008 0.8884476 8.857201e-02 5.619588e-04 9.564116e-03 15 90390874 90391932 1059 + 0.000 0.532 15.663
ENSG00000140575 E009 14.8392015 9.138855e-04 4.567114e-04 8.139371e-03 15 90426110 90426151 42 + 1.266 0.966 -1.081
ENSG00000140575 E010 24.9193404 1.887147e-03 6.495683e-05 1.648650e-03 15 90426152 90426266 115 + 1.474 1.198 -0.962
ENSG00000140575 E011 23.0275728 8.877984e-04 2.129580e-04 4.401710e-03 15 90429589 90429666 78 + 1.437 1.178 -0.903
ENSG00000140575 E012 0.0000000       15 90429667 90429849 183 +      
ENSG00000140575 E013 0.0000000       15 90431221 90431252 32 +      
ENSG00000140575 E014 24.7876914 1.740768e-03 1.115549e-02 8.637097e-02 15 90433719 90433795 77 + 1.445 1.276 -0.589
ENSG00000140575 E015 25.6808968 4.677230e-03 8.855595e-02 3.086382e-01 15 90439332 90439399 68 + 1.445 1.328 -0.407
ENSG00000140575 E016 31.3354711 1.887721e-03 3.469017e-02 1.779959e-01 15 90440502 90440615 114 + 1.531 1.405 -0.435
ENSG00000140575 E017 42.1548910 1.082465e-03 1.086754e-02 8.494635e-02 15 90441506 90441684 179 + 1.658 1.527 -0.447
ENSG00000140575 E018 29.8269032 4.525487e-04 4.055329e-01 6.882969e-01 15 90443394 90443478 85 + 1.486 1.439 -0.165
ENSG00000140575 E019 40.7189073 3.426149e-04 2.123722e-02 1.317954e-01 15 90448573 90448736 164 + 1.639 1.522 -0.398
ENSG00000140575 E020 21.7062957 6.310199e-04 1.945668e-04 4.091137e-03 15 90449559 90449643 85 + 1.414 1.148 -0.934
ENSG00000140575 E021 35.8377393 3.736892e-04 1.747521e-01 4.485571e-01 15 90452775 90452938 164 + 1.571 1.499 -0.247
ENSG00000140575 E022 44.7199484 3.317643e-04 5.385507e-01 7.871968e-01 15 90453132 90453292 161 + 1.651 1.622 -0.099
ENSG00000140575 E023 41.4992956 1.244262e-03 8.683367e-01 9.548371e-01 15 90454428 90454552 125 + 1.612 1.604 -0.029
ENSG00000140575 E024 55.6651020 2.646010e-04 2.671061e-01 5.603524e-01 15 90456152 90456315 164 + 1.750 1.703 -0.161
ENSG00000140575 E025 27.8796387 5.014213e-04 2.776953e-01 5.709305e-01 15 90466001 90466046 46 + 1.464 1.399 -0.224
ENSG00000140575 E026 34.5135243 3.843912e-04 1.957189e-01 4.760700e-01 15 90466047 90466091 45 + 1.555 1.485 -0.240
ENSG00000140575 E027 58.1751308 7.303114e-03 1.431389e-02 1.017413e-01 15 90466269 90466436 168 + 1.796 1.660 -0.463
ENSG00000140575 E028 24.6508910 5.681151e-04 1.384020e-06 6.163976e-05 15 90467450 90467481 32 + 1.481 1.148 -1.167
ENSG00000140575 E029 37.8418419 3.815444e-04 1.521235e-04 3.337152e-03 15 90467482 90467592 111 + 1.632 1.428 -0.700
ENSG00000140575 E030 62.0906803 5.297781e-03 6.512928e-02 2.570284e-01 15 90472840 90473010 171 + 1.812 1.718 -0.319
ENSG00000140575 E031 0.1176306 1.179022e-02 1.000000e+00   15 90473011 90473078 68 + 0.070 0.000 -13.237
ENSG00000140575 E032 0.7164293 1.432831e-01 4.193013e-01 6.988658e-01 15 90473548 90473714 167 + 0.272 0.128 -1.344
ENSG00000140575 E033 48.0378600 3.867231e-04 3.421378e-03 3.813003e-02 15 90473715 90473798 84 + 1.715 1.577 -0.471
ENSG00000140575 E034 0.0000000       15 90473799 90473895 97 +      
ENSG00000140575 E035 46.0274940 4.739362e-03 5.605633e-01 8.011188e-01 15 90473896 90473967 72 + 1.664 1.632 -0.108
ENSG00000140575 E036 43.0334904 3.754819e-03 2.602062e-01 5.528858e-01 15 90474064 90474133 70 + 1.603 1.663 0.204
ENSG00000140575 E037 0.2530140 2.722701e-01 1.225715e-01   15 90474134 90474239 106 + 0.000 0.227 13.479
ENSG00000140575 E038 0.4906674 1.586325e-02 5.034006e-01   15 90474322 90474483 162 + 0.130 0.227 0.978
ENSG00000140575 E039 0.1272623 1.237283e-02 2.596511e-01   15 90474484 90474484 1 + 0.000 0.128 13.524
ENSG00000140575 E040 89.1938750 2.508087e-04 3.302206e-01 6.227314e-01 15 90474485 90474693 209 + 1.947 1.914 -0.111
ENSG00000140575 E041 0.5993033 1.514216e-02 5.212587e-01 7.753053e-01 15 90474694 90474857 164 + 0.230 0.128 -1.022
ENSG00000140575 E042 0.1265070 1.230937e-02 2.596894e-01   15 90475689 90475754 66 + 0.000 0.128 13.525
ENSG00000140575 E043 78.3008516 1.563825e-03 2.823689e-02 1.571811e-01 15 90476663 90476818 156 + 1.909 1.821 -0.295
ENSG00000140575 E044 81.7858663 1.855747e-04 2.023464e-02 1.278958e-01 15 90477067 90477230 164 + 1.926 1.843 -0.279
ENSG00000140575 E045 108.9324864 3.369479e-04 1.479555e-01 4.095373e-01 15 90477665 90477889 225 + 2.037 1.992 -0.151
ENSG00000140575 E046 72.9008112 4.467479e-03 1.472699e-02 1.037434e-01 15 90481960 90482100 141 + 1.887 1.771 -0.390
ENSG00000140575 E047 56.6240752 3.008913e-03 8.906626e-01 9.636115e-01 15 90482197 90482281 85 + 1.744 1.737 -0.022
ENSG00000140575 E048 0.2459655 1.643602e-02 5.976367e-01   15 90482702 90482749 48 + 0.070 0.128 0.978
ENSG00000140575 E049 0.0000000       15 90483205 90483360 156 +      
ENSG00000140575 E050 118.6831884 1.234860e-03 9.354664e-01 9.814890e-01 15 90483361 90483593 233 + 2.060 2.057 -0.009
ENSG00000140575 E051 41.1348768 5.704065e-04 9.556226e-01 9.892828e-01 15 90484220 90484244 25 + 1.605 1.607 0.009
ENSG00000140575 E052 76.9141681 1.873503e-04 6.629170e-01 8.594862e-01 15 90484245 90484352 108 + 1.878 1.862 -0.053
ENSG00000140575 E053 58.5404719 4.726822e-03 6.856132e-01 8.701697e-01 15 90486030 90486094 65 + 1.762 1.742 -0.067
ENSG00000140575 E054 47.1214398 1.108201e-02 4.062522e-01 6.889881e-01 15 90486095 90486132 38 + 1.681 1.629 -0.176
ENSG00000140575 E055 1.7049491 8.423180e-03 4.817723e-01 7.467499e-01 15 90486133 90486558 426 + 0.379 0.486 0.563
ENSG00000140575 E056 0.3641302 2.147466e-01 1.000000e+00   15 90486743 90486882 140 + 0.130 0.128 -0.023
ENSG00000140575 E057 0.8705386 5.848016e-01 4.344941e-01 7.117749e-01 15 90486883 90486953 71 + 0.130 0.434 2.299
ENSG00000140575 E058 107.2844375 1.562315e-04 1.589460e-01 4.260733e-01 15 90486954 90487089 136 + 2.000 2.042 0.143
ENSG00000140575 E059 0.3709916 1.668947e-02 2.498272e-01   15 90487469 90487494 26 + 0.070 0.227 1.978
ENSG00000140575 E060 82.0803528 1.900386e-03 3.496049e-02 1.788616e-01 15 90487495 90487582 88 + 1.870 1.951 0.273
ENSG00000140575 E061 147.9675917 1.158855e-04 4.880685e-01 7.515202e-01 15 90491333 90491545 213 + 2.147 2.165 0.060
ENSG00000140575 E062 0.6356816 8.784753e-01 1.818994e-01 4.579554e-01 15 90491546 90491671 126 + 0.000 0.434 14.370
ENSG00000140575 E063 137.9227275 1.789297e-04 9.477469e-01 9.863423e-01 15 90492545 90492711 167 + 2.123 2.125 0.006
ENSG00000140575 E064 0.3801504 2.849021e-02 2.581561e-02   15 90494027 90494712 686 + 0.000 0.308 14.867
ENSG00000140575 E065 123.5529106 4.223880e-03 3.250661e-01 6.175802e-01 15 90494713 90494835 123 + 2.062 2.100 0.128
ENSG00000140575 E066 0.6275614 1.929399e-01 6.517832e-02 2.570589e-01 15 90496714 90497231 518 + 0.070 0.376 2.978
ENSG00000140575 E067 102.5330485 3.204660e-04 5.806311e-01 8.129849e-01 15 90497232 90497340 109 + 1.990 2.007 0.059
ENSG00000140575 E068 1605.0855674 2.865339e-05 9.600694e-25 3.864208e-22 15 90499995 90502239 2245 + 3.163 3.227 0.213

Help

Please Click HERE to learn more details about the results from DEXseq.