ENSG00000140678

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000268296 ENSG00000140678 No_inf pgKDN_inf ITGAX protein_coding protein_coding 231.01 216.4013 180.3195 3.182985 2.113521 -0.2631404 50.69106 29.79267 50.479881 3.971954 1.532788 0.7605528 0.21967500 0.13700 0.280025 0.143025 0.002402832 0.002402832 FALSE TRUE
ENST00000562138 ENSG00000140678 No_inf pgKDN_inf ITGAX protein_coding retained_intron 231.01 216.4013 180.3195 3.182985 2.113521 -0.2631404 16.61028 24.23144 3.967082 4.581488 2.314456 -2.6076933 0.06822500 0.11115 0.021600 -0.089550 0.140683390 0.002402832   FALSE
MSTRG.11071.1 ENSG00000140678 No_inf pgKDN_inf ITGAX protein_coding   231.01 216.4013 180.3195 3.182985 2.113521 -0.2631404 21.67351 16.64680 18.105734 5.163336 6.206937 0.1211318 0.09278333 0.07650 0.099800 0.023300 1.000000000 0.002402832 FALSE TRUE
MSTRG.11071.19 ENSG00000140678 No_inf pgKDN_inf ITGAX protein_coding   231.01 216.4013 180.3195 3.182985 2.113521 -0.2631404 12.94317 6.99416 8.399272 2.558736 3.817198 0.2637689 0.05331667 0.03265 0.047225 0.014575 0.988031313 0.002402832 FALSE TRUE
MSTRG.11071.25 ENSG00000140678 No_inf pgKDN_inf ITGAX protein_coding   231.01 216.4013 180.3195 3.182985 2.113521 -0.2631404 58.21025 55.48501 49.280992 2.016918 3.762320 -0.1710339 0.25479167 0.25630 0.272700 0.016400 0.880099861 0.002402832 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000140678 E001 0.1187032 1.182329e-02 4.371916e-01   16 31355134 31355140 7 + 0.104 0.000 -9.079
ENSG00000140678 E002 0.2458395 1.638059e-02 8.731489e-01   16 31355141 31355145 5 + 0.104 0.087 -0.297
ENSG00000140678 E003 0.8708855 2.700493e-02 3.868708e-01 6.727330e-01 16 31355146 31355165 20 + 0.188 0.323 1.025
ENSG00000140678 E004 1.2342905 3.317337e-02 7.693965e-01 9.108783e-01 16 31355166 31355173 8 + 0.319 0.366 0.288
ENSG00000140678 E005 1.2342905 3.317337e-02 7.693965e-01 9.108783e-01 16 31355174 31355175 2 + 0.319 0.366 0.288
ENSG00000140678 E006 1.3615528 1.950812e-02 5.782612e-01 8.115317e-01 16 31355176 31355181 6 + 0.319 0.406 0.510
ENSG00000140678 E007 1.9685335 6.977368e-03 9.292554e-01 9.791822e-01 16 31355182 31355187 6 + 0.462 0.475 0.065
ENSG00000140678 E008 16.7947684 8.017877e-04 1.691929e-01 4.408334e-01 16 31355188 31355221 34 + 1.187 1.286 0.350
ENSG00000140678 E009 27.2782780 4.998032e-04 1.019465e-01 3.335387e-01 16 31355222 31355291 70 + 1.391 1.486 0.326
ENSG00000140678 E010 12.5756891 1.117984e-03 4.573482e-01 7.292567e-01 16 31355893 31355898 6 + 1.093 1.154 0.217
ENSG00000140678 E011 45.4948269 3.122856e-04 1.962343e-01 4.768715e-01 16 31355899 31355998 100 + 1.695 1.637 -0.196
ENSG00000140678 E012 0.4896297 1.578313e-02 8.381743e-01   16 31355999 31356278 280 + 0.188 0.159 -0.297
ENSG00000140678 E013 61.6456750 2.234638e-04 7.157732e-02 2.711181e-01 16 31356625 31356728 104 + 1.831 1.762 -0.234
ENSG00000140678 E014 50.1981128 1.153198e-03 3.230290e-01 6.158114e-01 16 31357031 31357101 71 + 1.729 1.686 -0.149
ENSG00000140678 E015 0.8626665 1.278322e-02 9.150535e-01 9.733452e-01 16 31357102 31357252 151 + 0.259 0.275 0.118
ENSG00000140678 E016 51.2192713 3.362485e-03 8.229643e-02 2.953837e-01 16 31357253 31357333 81 + 1.759 1.676 -0.283
ENSG00000140678 E017 36.4285088 4.116163e-04 1.053283e-02 8.312521e-02 16 31357334 31357364 31 + 1.637 1.510 -0.433
ENSG00000140678 E018 87.6121597 9.059237e-04 2.410812e-01 5.304750e-01 16 31357365 31358712 1348 + 1.966 1.926 -0.135
ENSG00000140678 E019 37.1214008 3.727628e-04 1.357666e-03 1.895736e-02 16 31358895 31359699 805 + 1.478 1.640 0.554
ENSG00000140678 E020 76.2068623 1.319982e-03 1.722320e-03 2.274525e-02 16 31359700 31359830 131 + 1.946 1.829 -0.394
ENSG00000140678 E021 38.9087427 3.514440e-04 2.379156e-02 1.411788e-01 16 31359920 31359934 15 + 1.655 1.547 -0.370
ENSG00000140678 E022 33.4118659 5.230076e-04 4.837343e-02 2.165302e-01 16 31359935 31359936 2 + 1.588 1.486 -0.350
ENSG00000140678 E023 91.3939168 5.660906e-04 1.293044e-02 9.497349e-02 16 31359937 31360065 129 + 2.006 1.924 -0.274
ENSG00000140678 E024 121.1743645 1.769620e-04 3.326971e-02 1.733857e-01 16 31360310 31360463 154 + 2.115 2.056 -0.198
ENSG00000140678 E025 59.6490702 6.447262e-04 7.207564e-05 1.802192e-03 16 31360464 31360662 199 + 1.678 1.842 0.553
ENSG00000140678 E026 32.8177581 1.613325e-02 2.189562e-02 1.343479e-01 16 31360663 31360779 117 + 1.419 1.591 0.589
ENSG00000140678 E027 88.4499541 2.319841e-03 1.377372e-06 6.144514e-05 16 31360780 31361062 283 + 1.831 2.018 0.631
ENSG00000140678 E028 124.3305444 3.844612e-03 7.652176e-02 2.828874e-01 16 31361063 31361213 151 + 2.131 2.064 -0.224
ENSG00000140678 E029 77.1332710 1.920635e-04 7.072185e-02 2.693533e-01 16 31361836 31361909 74 + 1.923 1.861 -0.210
ENSG00000140678 E030 90.6649789 1.722044e-04 6.146667e-01 8.326315e-01 16 31362075 31362204 130 + 1.967 1.951 -0.054
ENSG00000140678 E031 87.4147272 6.198957e-04 4.467810e-01 7.210777e-01 16 31362611 31362753 143 + 1.957 1.931 -0.086
ENSG00000140678 E032 2.5718990 8.806998e-03 8.043939e-01 9.274484e-01 16 31362875 31362934 60 + 0.570 0.535 -0.159
ENSG00000140678 E033 54.3990673 2.662869e-03 9.704608e-02 3.245085e-01 16 31362935 31363075 141 + 1.781 1.705 -0.258
ENSG00000140678 E034 31.2757607 7.240260e-04 3.497091e-01 6.399488e-01 16 31363165 31363206 42 + 1.533 1.482 -0.173
ENSG00000140678 E035 115.2596097 7.966190e-04 3.753369e-02 1.867819e-01 16 31363207 31363374 168 + 2.096 2.033 -0.211
ENSG00000140678 E036 0.0000000       16 31368867 31368923 57 +      
ENSG00000140678 E037 24.4374135 5.891162e-03 1.234751e-06 5.596225e-05 16 31368924 31369980 1057 + 1.171 1.519 1.210
ENSG00000140678 E038 12.1985419 2.788240e-03 6.145423e-04 1.023301e-02 16 31369981 31370098 118 + 0.920 1.222 1.098
ENSG00000140678 E039 2.7055117 2.580859e-01 8.234839e-01 9.359136e-01 16 31370099 31370167 69 + 0.536 0.587 0.234
ENSG00000140678 E040 42.8486087 4.368763e-04 1.577085e-12 1.996678e-10 16 31370168 31371083 916 + 1.405 1.757 1.200
ENSG00000140678 E041 108.2129774 6.059882e-04 9.269568e-02 3.162055e-01 16 31371084 31371214 131 + 2.063 2.011 -0.173
ENSG00000140678 E042 11.2447785 1.188571e-03 9.392652e-06 3.234887e-04 16 31371215 31371333 119 + 0.808 1.216 1.510
ENSG00000140678 E043 132.6889165 1.662584e-04 2.510618e-01 5.422596e-01 16 31371334 31371473 140 + 2.139 2.109 -0.102
ENSG00000140678 E044 70.4802146 2.243371e-04 6.110600e-01 8.308705e-01 16 31371474 31371497 24 + 1.839 1.858 0.062
ENSG00000140678 E045 20.9410580 6.941691e-04 1.357949e-07 7.701329e-06 16 31371498 31371629 132 + 1.093 1.460 1.288
ENSG00000140678 E046 175.7468614 1.006100e-04 7.765073e-01 9.141542e-01 16 31371630 31371784 155 + 2.247 2.240 -0.022
ENSG00000140678 E047 8.7464809 3.360033e-02 2.369399e-03 2.892512e-02 16 31372183 31372377 195 + 0.728 1.111 1.458
ENSG00000140678 E048 159.4269134 1.185433e-04 1.793069e-01 4.543947e-01 16 31372378 31372509 132 + 2.182 2.215 0.109
ENSG00000140678 E049 12.1990844 1.847410e-03 4.971815e-01 7.579137e-01 16 31372510 31372596 87 + 1.084 1.140 0.203
ENSG00000140678 E050 108.0611361 1.473962e-04 5.356284e-02 2.304266e-01 16 31372597 31372670 74 + 2.000 2.057 0.191
ENSG00000140678 E051 181.3760777 9.456146e-05 6.661130e-02 2.599952e-01 16 31373249 31373390 142 + 2.233 2.274 0.139
ENSG00000140678 E052 177.8672484 1.012305e-04 1.200394e-01 3.662709e-01 16 31376799 31376915 117 + 2.228 2.263 0.119
ENSG00000140678 E053 132.8966017 1.292533e-04 9.487628e-01 9.867620e-01 16 31377000 31377079 80 + 2.122 2.123 0.006
ENSG00000140678 E054 127.6962508 2.172684e-04 3.462320e-01 6.370827e-01 16 31377182 31377265 84 + 2.120 2.094 -0.086
ENSG00000140678 E055 28.3376727 5.367062e-04 6.960866e-11 7.123859e-09 16 31378005 31379567 1563 + 1.195 1.593 1.383
ENSG00000140678 E056 126.5136486 8.798936e-04 5.332831e-01 7.837814e-01 16 31379568 31379646 79 + 2.112 2.093 -0.061
ENSG00000140678 E057 8.5265462 1.680304e-03 2.693128e-06 1.096448e-04 16 31379647 31379756 110 + 0.629 1.126 1.925
ENSG00000140678 E058 162.9942466 1.204675e-04 9.121727e-01 9.720229e-01 16 31379757 31379864 108 + 2.212 2.209 -0.009
ENSG00000140678 E059 150.8167790 3.930845e-04 5.393282e-01 7.877838e-01 16 31379982 31380065 84 + 2.168 2.184 0.053
ENSG00000140678 E060 186.6607288 9.988224e-05 3.344753e-01 6.263095e-01 16 31380266 31380379 114 + 2.257 2.278 0.072
ENSG00000140678 E061 155.1359290 1.221960e-04 5.411120e-01 7.888017e-01 16 31380523 31380624 102 + 2.181 2.196 0.050
ENSG00000140678 E062 154.5859752 1.405280e-04 8.198517e-01 9.345044e-01 16 31380897 31381007 111 + 2.185 2.190 0.019
ENSG00000140678 E063 133.8785194 1.323536e-04 3.561368e-01 6.459472e-01 16 31381803 31381896 94 + 2.112 2.136 0.082
ENSG00000140678 E064 335.1195475 1.473801e-04 5.267308e-02 2.280724e-01 16 31381897 31382266 370 + 2.541 2.508 -0.109
ENSG00000140678 E065 44.9347435 3.692578e-04 4.203939e-01 6.997506e-01 16 31382267 31382290 24 + 1.678 1.642 -0.123
ENSG00000140678 E066 321.9902137 6.852243e-05 4.325480e-02 2.028436e-01 16 31382291 31382467 177 + 2.524 2.490 -0.113
ENSG00000140678 E067 613.9370757 2.385862e-04 1.064874e-01 3.417202e-01 16 31382468 31382999 532 + 2.796 2.775 -0.070

Help

Please Click HERE to learn more details about the results from DEXseq.