ENSG00000140718

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000460382 ENSG00000140718 No_inf pgKDN_inf FTO protein_coding protein_coding 27.24624 14.33984 42.92518 6.05991 11.23188 1.581125 1.3182530 2.6377664 0.7074569 0.1435199 0.7074569 -1.8838118 0.11050000 0.257275 0.012550 -0.244725 0.01123344 0.01123344 FALSE FALSE
ENST00000464071 ENSG00000140718 No_inf pgKDN_inf FTO protein_coding nonsense_mediated_decay 27.24624 14.33984 42.92518 6.05991 11.23188 1.581125 1.4006653 0.0000000 2.2578697 0.0000000 0.7584163 7.8251940 0.07019167 0.000000 0.102750 0.102750 0.28199702 0.01123344 FALSE TRUE
ENST00000636030 ENSG00000140718 No_inf pgKDN_inf FTO protein_coding protein_coding_CDS_not_defined 27.24624 14.33984 42.92518 6.05991 11.23188 1.581125 1.9458934 1.0554346 1.7035349 0.6110472 0.7473920 0.6855336 0.11780833 0.117975 0.031700 -0.086275 0.92136578 0.01123344 FALSE TRUE
ENST00000637049 ENSG00000140718 No_inf pgKDN_inf FTO protein_coding nonsense_mediated_decay 27.24624 14.33984 42.92518 6.05991 11.23188 1.581125 1.4058447 1.5908897 1.0961005 0.1850066 0.2658822 -0.5333915 0.10625833 0.152925 0.054075 -0.098850 0.35853189 0.01123344 FALSE TRUE
ENST00000637062 ENSG00000140718 No_inf pgKDN_inf FTO protein_coding protein_coding 27.24624 14.33984 42.92518 6.05991 11.23188 1.581125 0.2604084 0.7812253 0.0000000 0.5034354 0.0000000 -6.3060166 0.02825000 0.084750 0.000000 -0.084750 0.37430451 0.01123344   FALSE
ENST00000637562 ENSG00000140718 No_inf pgKDN_inf FTO protein_coding nonsense_mediated_decay 27.24624 14.33984 42.92518 6.05991 11.23188 1.581125 1.0511484 0.5770976 1.9122890 0.5770976 1.1228026 1.7111530 0.09510000 0.082975 0.126675 0.043700 0.91489087 0.01123344 TRUE TRUE
ENST00000640179 ENSG00000140718 No_inf pgKDN_inf FTO protein_coding protein_coding 27.24624 14.33984 42.92518 6.05991 11.23188 1.581125 18.6979386 6.2253965 34.3835022 6.2253965 11.5092507 2.4635828 0.40593333 0.191950 0.637500 0.445550 0.32344800 0.01123344   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000140718 E001 0.0000000       16 53701692 53701821 130 +      
ENSG00000140718 E002 0.0000000       16 53703963 53704068 106 +      
ENSG00000140718 E003 0.0000000       16 53704069 53704155 87 +      
ENSG00000140718 E004 0.0000000       16 53704156 53704156 1 +      
ENSG00000140718 E005 0.0000000       16 53704157 53704157 1 +      
ENSG00000140718 E006 0.3641952 0.0167548198 0.67048685   16 53704158 53704181 24 + 0.163 0.101 -0.799
ENSG00000140718 E007 0.3641952 0.0167548198 0.67048685   16 53704182 53704184 3 + 0.163 0.101 -0.799
ENSG00000140718 E008 1.8010205 0.0188922033 0.03608041 0.18235974 16 53704185 53704229 45 + 0.573 0.252 -1.799
ENSG00000140718 E009 0.0000000       16 53711361 53711454 94 +      
ENSG00000140718 E010 0.0000000       16 53764162 53764280 119 +      
ENSG00000140718 E011 3.0340848 0.0053563379 0.28567835 0.57931590 16 53810140 53810217 78 + 0.668 0.527 -0.629
ENSG00000140718 E012 0.0000000       16 53814670 53814848 179 +      
ENSG00000140718 E013 8.6229461 0.0016502905 0.21625182 0.50237241 16 53825864 53826360 497 + 1.034 0.922 -0.418
ENSG00000140718 E014 3.9269571 0.0269924678 0.48935704 0.75230869 16 53826361 53826491 131 + 0.646 0.737 0.382
ENSG00000140718 E015 3.7622795 0.0052304480 0.37972744 0.66637013 16 53844155 53844248 94 + 0.727 0.618 -0.462
ENSG00000140718 E016 2.0473617 0.0071080182 0.15057638 0.41316577 16 53844249 53844298 50 + 0.573 0.364 -1.062
ENSG00000140718 E017 3.8669788 0.0038985744 0.07698301 0.28381992 16 53873786 53873865 80 + 0.780 0.559 -0.936
ENSG00000140718 E018 5.9186164 0.0830012488 0.09138060 0.31396712 16 53879844 53879987 144 + 0.943 0.694 -0.979
ENSG00000140718 E019 0.0000000       16 53886917 53886929 13 +      
ENSG00000140718 E020 0.1268540 0.0124468016 0.47022731   16 53886930 53886953 24 + 0.000 0.101 12.546
ENSG00000140718 E021 0.1268540 0.0124468016 0.47022731   16 53886954 53886975 22 + 0.000 0.101 12.546
ENSG00000140718 E022 0.0000000       16 53887869 53887916 48 +      
ENSG00000140718 E023 4.3794856 0.0043328798 0.55330684 0.79640666 16 53888832 53888893 62 + 0.763 0.693 -0.284
ENSG00000140718 E024 3.7822958 0.0302776564 0.91160477 0.97179299 16 53888894 53888951 58 + 0.688 0.670 -0.079
ENSG00000140718 E025 0.0000000       16 53911256 53911484 229 +      
ENSG00000140718 E026 0.0000000       16 53923056 53923144 89 +      
ENSG00000140718 E027 3.3879250 0.0268669142 0.29066460 0.58417634 16 53933985 53934029 45 + 0.708 0.559 -0.647
ENSG00000140718 E028 6.1129868 0.0277893454 0.84177694 0.94321060 16 53934030 53934109 80 + 0.841 0.863 0.086
ENSG00000140718 E029 0.3811266 0.0219946853 0.08044961   16 53935572 53935847 276 + 0.000 0.252 13.956
ENSG00000140718 E030 0.3720293 0.0166808980 0.50378433   16 53937249 53937889 641 + 0.089 0.183 1.201
ENSG00000140718 E031 0.1170040 0.0117637476 0.61402760   16 53956683 53956789 107 + 0.089 0.000 -13.183
ENSG00000140718 E032 0.1268540 0.0124468016 0.47022731   16 53965721 53965858 138 + 0.000 0.101 12.546
ENSG00000140718 E033 0.1271363 0.0123644336 0.47042163   16 53979371 53979499 129 + 0.000 0.101 12.546
ENSG00000140718 E034 0.0000000       16 53984938 53984954 17 +      
ENSG00000140718 E035 0.0000000       16 54008428 54008560 133 +      
ENSG00000140718 E036 0.0000000       16 54013378 54013511 134 +      
ENSG00000140718 E037 0.1265070 0.0124792483 0.47015106   16 54039345 54039434 90 + 0.000 0.101 12.546
ENSG00000140718 E038 2.2206047 0.0065784457 0.22084142 0.50782673 16 54039546 54040726 1181 + 0.415 0.590 0.853
ENSG00000140718 E039 0.0000000       16 54061662 54061720 59 +      
ENSG00000140718 E040 0.0000000       16 54063637 54063942 306 +      
ENSG00000140718 E041 0.1170040 0.0117637476 0.61402760   16 54069896 54072540 2645 + 0.089 0.000 -13.183
ENSG00000140718 E042 7.4659501 0.0022031040 0.68521254 0.86988638 16 54111762 54111889 128 + 0.907 0.948 0.154
ENSG00000140718 E043 92.3243527 0.0002505176 0.01127337 0.08703376 16 54111890 54118380 6491 + 1.943 1.996 0.178
ENSG00000140718 E044 0.1268540 0.0124468016 0.47022731   16 54118381 54118806 426 + 0.000 0.101 12.546
ENSG00000140718 E045 1.3517956 0.0115867062 0.59925167 0.82431138 16 54118807 54121375 2569 + 0.331 0.411 0.464
ENSG00000140718 E046 0.3731018 0.0167707592 0.50423109   16 54121376 54121941 566 + 0.089 0.183 1.201
ENSG00000140718 E047 0.0000000       16 54149687 54149689 3 +      
ENSG00000140718 E048 0.0000000       16 54149690 54149762 73 +      
ENSG00000140718 E049 0.0000000       16 54152114 54152746 633 +      
ENSG00000140718 E050 0.1272623 0.0124121274 0.47035965   16 54152747 54153448 702 + 0.000 0.101 12.546
ENSG00000140718 E051 0.0000000       16 54157114 54158512 1399 +      

Help

Please Click HERE to learn more details about the results from DEXseq.