ENSG00000140750

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000289968 ENSG00000140750 No_inf pgKDN_inf ARHGAP17 protein_coding protein_coding 33.13356 44.54889 25.39985 1.174476 0.8376609 -0.8103253 4.8525389 1.939920 5.053435 0.7346650 1.8592224 1.3767014 0.16638333 0.043200 0.199150 0.155950 0.605211993 0.004759871 FALSE TRUE
ENST00000303665 ENSG00000140750 No_inf pgKDN_inf ARHGAP17 protein_coding protein_coding 33.13356 44.54889 25.39985 1.174476 0.8376609 -0.8103253 2.6449033 7.934710 0.000000 2.6979452 0.0000000 -9.6338507 0.05816667 0.174500 0.000000 -0.174500 0.022550590 0.004759871 FALSE TRUE
ENST00000571406 ENSG00000140750 No_inf pgKDN_inf ARHGAP17 protein_coding protein_coding 33.13356 44.54889 25.39985 1.174476 0.8376609 -0.8103253 0.5883342 0.000000 1.765003 0.0000000 1.7650026 7.4716774 0.02198333 0.000000 0.065950 0.065950 0.811681097 0.004759871 FALSE TRUE
ENST00000571843 ENSG00000140750 No_inf pgKDN_inf ARHGAP17 protein_coding protein_coding 33.13356 44.54889 25.39985 1.174476 0.8376609 -0.8103253 8.7638446 17.082979 1.171195 1.8565423 1.1711952 -3.8550846 0.23193333 0.381650 0.044900 -0.336750 0.004759871 0.004759871 FALSE TRUE
ENST00000573703 ENSG00000140750 No_inf pgKDN_inf ARHGAP17 protein_coding retained_intron 33.13356 44.54889 25.39985 1.174476 0.8376609 -0.8103253 1.9058395 3.381946 1.037686 0.5932742 0.4468245 -1.6949070 0.05359167 0.076225 0.040225 -0.036000 0.716337546 0.004759871 FALSE FALSE
MSTRG.10872.1 ENSG00000140750 No_inf pgKDN_inf ARHGAP17 protein_coding   33.13356 44.54889 25.39985 1.174476 0.8376609 -0.8103253 6.2300873 6.409094 6.684139 3.9378415 2.9445460 0.0605287 0.20482500 0.147975 0.270275 0.122300 0.837094506 0.004759871 FALSE TRUE
MSTRG.10872.2 ENSG00000140750 No_inf pgKDN_inf ARHGAP17 protein_coding   33.13356 44.54889 25.39985 1.174476 0.8376609 -0.8103253 3.0556442 3.575930 2.636177 1.9598518 1.6562916 -0.4384375 0.09350833 0.080125 0.101825 0.021700 1.000000000 0.004759871 TRUE TRUE
MSTRG.10872.3 ENSG00000140750 No_inf pgKDN_inf ARHGAP17 protein_coding   33.13356 44.54889 25.39985 1.174476 0.8376609 -0.8103253 1.0845543 0.000000 3.253663 0.0000000 2.4201576 8.3503483 0.04167500 0.000000 0.125025 0.125025 0.383391786 0.004759871 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000140750 E001 0.1271363 0.0123593219 8.550640e-01   16 24919354 24919385 32 - 0.000 0.078 9.195
ENSG00000140750 E002 0.3815350 0.0275512222 2.225204e-01   16 24919386 24919388 3 - 0.000 0.201 13.047
ENSG00000140750 E003 0.6171771 0.0196711067 9.691559e-01 0.9936412263 16 24919389 24919392 4 - 0.207 0.201 -0.049
ENSG00000140750 E004 0.6171771 0.0196711067 9.691559e-01 0.9936412263 16 24919393 24919394 2 - 0.207 0.201 -0.049
ENSG00000140750 E005 0.6171771 0.0196711067 9.691559e-01 0.9936412263 16 24919395 24919396 2 - 0.207 0.201 -0.049
ENSG00000140750 E006 1.1156520 0.0118724627 7.211030e-01 0.8876706011 16 24919397 24919397 1 - 0.282 0.338 0.366
ENSG00000140750 E007 3.4615353 0.0043054759 7.093566e-01 0.8824237303 16 24919398 24919413 16 - 0.607 0.657 0.214
ENSG00000140750 E008 91.2025565 0.0001782581 1.976690e-03 0.0253412856 16 24919414 24919891 478 - 1.888 1.984 0.325
ENSG00000140750 E009 95.7114753 0.0026667671 1.549546e-01 0.4205510467 16 24919892 24920247 356 - 1.939 1.990 0.169
ENSG00000140750 E010 15.9747333 0.0009891802 3.160749e-01 0.6089801686 16 24920248 24920260 13 - 1.168 1.243 0.267
ENSG00000140750 E011 7.2734304 0.0128885954 7.039462e-04 0.0114007147 16 24920261 24921004 744 - 0.607 1.018 1.629
ENSG00000140750 E012 11.6445732 0.0041706610 4.307283e-01 0.7085399544 16 24927684 24927732 49 - 1.044 1.113 0.252
ENSG00000140750 E013 3.3008827 0.0043603975 1.879324e-01 0.4661489790 16 24929613 24929660 48 - 0.722 0.551 -0.741
ENSG00000140750 E014 84.5460541 0.0002617619 1.523825e-03 0.0207319222 16 24930784 24931404 621 - 1.850 1.954 0.350
ENSG00000140750 E015 29.3873243 0.0077321089 9.799453e-01 0.9977097140 16 24935470 24935639 170 - 1.468 1.470 0.007
ENSG00000140750 E016 3.5867203 0.1426149593 7.650499e-01 0.9086189462 16 24935640 24936827 1188 - 0.607 0.675 0.292
ENSG00000140750 E017 9.4243292 0.0240059041 2.067170e-05 0.0006345978 16 24939364 24939597 234 - 1.234 0.772 -1.718
ENSG00000140750 E018 0.6159185 0.0253292811 9.705708e-01 0.9941399880 16 24939598 24939921 324 - 0.207 0.201 -0.049
ENSG00000140750 E019 0.4990093 0.0253395287 5.778794e-01   16 24941696 24941986 291 - 0.116 0.201 0.951
ENSG00000140750 E020 25.0849457 0.0010273968 7.191043e-01 0.8868074864 16 24941987 24942143 157 - 1.389 1.411 0.077
ENSG00000140750 E021 16.6340925 0.0029815563 5.961570e-01 0.8224891697 16 24943771 24943834 64 - 1.257 1.218 -0.137
ENSG00000140750 E022 14.0739348 0.0093490886 9.038735e-01 0.9690690603 16 24943835 24943862 28 - 1.159 1.169 0.036
ENSG00000140750 E023 24.6188834 0.0044744045 3.763434e-01 0.6634971247 16 24947482 24947595 114 - 1.430 1.373 -0.198
ENSG00000140750 E024 0.6244813 0.0149858799 3.729106e-01 0.6605979011 16 24948982 24949127 146 - 0.116 0.252 1.366
ENSG00000140750 E025 1.3697385 0.0094491851 4.123351e-01 0.6936353441 16 24949128 24949403 276 - 0.282 0.410 0.781
ENSG00000140750 E026 24.0415416 0.0006285528 7.005125e-01 0.8779733905 16 24949404 24949484 81 - 1.399 1.376 -0.080
ENSG00000140750 E027 20.7953786 0.0016722453 2.931514e-01 0.5867423290 16 24952289 24952370 82 - 1.367 1.298 -0.239
ENSG00000140750 E028 16.5230009 0.0051621771 8.474601e-03 0.0718662113 16 24952931 24953042 112 - 1.343 1.145 -0.698
ENSG00000140750 E029 14.6798899 0.0009816978 3.247643e-03 0.0366363429 16 24954603 24954691 89 - 1.306 1.086 -0.778
ENSG00000140750 E030 11.0468103 0.0013005581 9.967661e-02 0.3298738786 16 24954692 24954730 39 - 1.150 1.010 -0.506
ENSG00000140750 E031 6.0438920 0.0349046649 9.557372e-05 0.0022879153 16 24954731 24957536 2806 - 0.402 0.975 2.470
ENSG00000140750 E032 17.8928046 0.0007877695 8.378567e-01 0.9419273083 16 24959671 24959752 82 - 1.271 1.258 -0.049
ENSG00000140750 E033 9.4849091 0.0024983907 5.162838e-01 0.7720208691 16 24959911 24959916 6 - 1.044 0.984 -0.219
ENSG00000140750 E034 12.1715984 0.0011871990 2.059265e-01 0.4894214712 16 24959917 24959979 63 - 1.168 1.065 -0.371
ENSG00000140750 E035 0.0000000       16 24959980 24959981 2 -      
ENSG00000140750 E036 8.7142938 0.0046968524 1.493106e-01 0.4115499330 16 24964197 24964244 48 - 1.056 0.918 -0.512
ENSG00000140750 E037 7.4732753 0.0037534331 7.144958e-02 0.2708465404 16 24964245 24964283 39 - 1.019 0.839 -0.681
ENSG00000140750 E038 6.9845327 0.0031981358 1.339371e-01 0.3888551196 16 24964284 24964308 25 - 0.979 0.826 -0.583
ENSG00000140750 E039 12.9958192 0.0014877294 6.394747e-02 0.2547156993 16 24968351 24968427 77 - 1.219 1.072 -0.525
ENSG00000140750 E040 0.0000000       16 24968562 24968660 99 -      
ENSG00000140750 E041 15.5778937 0.0053779999 5.622837e-02 0.2364432208 16 24968661 24968768 108 - 1.292 1.145 -0.520
ENSG00000140750 E042 5.1536951 0.0766275900 3.953064e-01 0.6801000576 16 24968769 24968772 4 - 0.851 0.726 -0.496
ENSG00000140750 E043 8.9677513 0.0376820096 3.026269e-01 0.5957542072 16 24970507 24970580 74 - 1.056 0.938 -0.436
ENSG00000140750 E044 0.3806233 0.0158798176 2.199070e-01   16 24972596 24972633 38 - 0.000 0.201 13.096
ENSG00000140750 E045 12.4865784 0.0018946182 7.535317e-01 0.9030526382 16 24977215 24977319 105 - 1.100 1.126 0.095
ENSG00000140750 E046 0.0000000       16 24977320 24977456 137 -      
ENSG00000140750 E047 7.1659538 0.0018852609 8.476400e-01 0.9460045408 16 24978966 24979005 40 - 0.887 0.907 0.077
ENSG00000140750 E048 0.0000000       16 25013863 25013956 94 -      
ENSG00000140750 E049 9.2274753 0.0015176241 3.973402e-01 0.6814883693 16 25015209 25015394 186 - 1.044 0.966 -0.286
ENSG00000140750 E050 0.0000000       16 25015501 25015666 166 -      

Help

Please Click HERE to learn more details about the results from DEXseq.