ENSG00000140848

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000290776 ENSG00000140848 No_inf pgKDN_inf CPNE2 protein_coding protein_coding 119.1841 278.6227 51.92036 2.280196 0.9631673 -2.423714 87.95608 194.35444 45.593108 10.520306 1.294660 -2.091560 0.82060000 0.697375 0.8793 0.181925 0.00748263 0.00748263 FALSE TRUE
MSTRG.11222.6 ENSG00000140848 No_inf pgKDN_inf CPNE2 protein_coding   119.1841 278.6227 51.92036 2.280196 0.9631673 -2.423714 13.38488 36.03923 2.865039 6.831128 1.826325 -3.648315 0.07623333 0.129475 0.0538 -0.075675 0.37447168 0.00748263 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000140848 E001 4.4418740 3.140170e-03 0.0004609797 0.008205439 16 57092583 57092606 24 + 0.965 0.511 -1.878
ENSG00000140848 E002 52.1999012 9.995466e-03 0.0264844771 0.150806402 16 57092607 57092790 184 + 1.692 1.546 -0.499
ENSG00000140848 E003 0.6357773 1.618523e-02 0.6652971274 0.860804490 16 57093950 57094091 142 + 0.000 0.179 11.037
ENSG00000140848 E004 0.4985390 2.800841e-02 0.5383215704   16 57106051 57106174 124 + 0.201 0.116 -0.945
ENSG00000140848 E005 1.5158220 9.059575e-03 0.5212962703 0.775305306 16 57110551 57110707 157 + 0.201 0.326 0.930
ENSG00000140848 E006 134.5384851 1.201580e-04 0.0003419514 0.006469211 16 57110708 57110922 215 + 2.076 1.954 -0.411
ENSG00000140848 E007 4.2805077 4.999216e-02 0.6679145611 0.861807848 16 57112842 57113243 402 + 0.525 0.608 0.377
ENSG00000140848 E008 2.5022003 6.594467e-03 0.5307886094 0.781639668 16 57113244 57113287 44 + 0.525 0.420 -0.530
ENSG00000140848 E009 172.7938540 2.930056e-04 0.6459299977 0.850210974 16 57113288 57113467 180 + 2.068 2.083 0.050
ENSG00000140848 E010 102.1960397 2.093506e-03 0.5315615613 0.782179937 16 57115476 57115550 75 + 1.879 1.851 -0.094
ENSG00000140848 E011 116.3878604 1.463156e-04 0.0543295072 0.232122084 16 57117496 57117567 72 + 1.973 1.900 -0.245
ENSG00000140848 E012 60.4211636 2.712677e-04 0.0631805390 0.252859931 16 57119195 57119198 4 + 1.713 1.616 -0.327
ENSG00000140848 E013 127.0860997 1.399704e-04 0.1238308964 0.372674268 16 57119199 57119278 80 + 1.997 1.940 -0.189
ENSG00000140848 E014 137.6271814 1.236519e-04 0.6562339492 0.856079474 16 57119561 57119650 90 + 1.997 1.981 -0.054
ENSG00000140848 E015 146.1004724 3.128725e-04 0.0122085407 0.091531298 16 57121093 57121191 99 + 2.081 1.996 -0.285
ENSG00000140848 E016 156.7129278 1.499852e-04 0.1008474569 0.331491147 16 57121674 57121760 87 + 2.085 2.031 -0.181
ENSG00000140848 E017 4.7888629 1.277304e-02 0.4551254359 0.727763505 16 57123306 57123413 108 + 0.525 0.650 0.558
ENSG00000140848 E018 127.3204641 1.392486e-04 0.6377793386 0.845466379 16 57123414 57123473 60 + 1.965 1.947 -0.059
ENSG00000140848 E019 7.0568281 3.105818e-03 0.3770418649 0.664142393 16 57123474 57124247 774 + 0.656 0.785 0.529
ENSG00000140848 E020 1.5233436 9.171089e-03 0.1264359289 0.376896888 16 57124248 57124469 222 + 0.000 0.347 12.381
ENSG00000140848 E021 6.0673040 1.695628e-02 0.0767580133 0.283246308 16 57124470 57125276 807 + 0.442 0.747 1.377
ENSG00000140848 E022 1.3880221 5.026768e-02 0.6150820932 0.832938049 16 57125277 57125363 87 + 0.201 0.305 0.792
ENSG00000140848 E023 6.0462817 2.178678e-02 0.4078962951 0.690309667 16 57125364 57125859 496 + 0.596 0.731 0.575
ENSG00000140848 E024 240.3302592 8.229337e-05 0.0356628005 0.181009035 16 57125860 57125993 134 + 2.172 2.231 0.196
ENSG00000140848 E025 190.4976293 5.712993e-04 0.1181426682 0.363091675 16 57127849 57127903 55 + 2.079 2.129 0.171
ENSG00000140848 E026 0.5082940 1.677342e-01 1.0000000000 1.000000000 16 57129052 57129150 99 + 0.000 0.148 10.015
ENSG00000140848 E027 171.5234547 1.150722e-03 0.6485057186 0.851591561 16 57134775 57134826 52 + 2.091 2.075 -0.053
ENSG00000140848 E028 273.7936344 3.195027e-04 0.5536183569 0.796703465 16 57137149 57137282 134 + 2.266 2.281 0.051
ENSG00000140848 E029 26.3862432 5.087608e-04 0.0016876557 0.022391642 16 57145640 57146084 445 + 1.017 1.315 1.063
ENSG00000140848 E030 425.3477501 6.406068e-05 0.1679219075 0.438805327 16 57146085 57146321 237 + 2.446 2.473 0.092
ENSG00000140848 E031 33.4486669 6.015659e-03 0.0016158865 0.021663242 16 57146322 57147550 1229 + 1.126 1.412 1.009
ENSG00000140848 E032 478.3816960 6.480726e-05 0.0043103668 0.044721750 16 57147551 57148369 819 + 2.473 2.528 0.181

Help

Please Click HERE to learn more details about the results from DEXseq.