ENSG00000140931

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000567572 ENSG00000140931 No_inf pgKDN_inf CMTM3 protein_coding protein_coding 161.2385 235.8542 133.6426 7.255013 1.993834 -0.8194688 134.0091 192.7976 121.1326 4.822789 1.910101 -0.6704553 0.8347083 0.81805 0.906675 0.088625 0.0019382 7.678721e-08 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000140931 E001 0.1265070 1.233329e-02 1.000000000   16 66603874 66603909 36 + 0.000 0.071 9.337
ENSG00000140931 E002 0.3646036 1.670167e-02 0.263724239   16 66604032 66604099 68 + 0.224 0.071 -1.922
ENSG00000140931 E003 0.8720809 1.290492e-02 0.739897333 0.89686991 16 66604100 66604156 57 + 0.224 0.276 0.400
ENSG00000140931 E004 0.7615936 1.749199e-02 0.060202538 0.24628062 16 66604157 66604182 26 + 0.000 0.315 13.254
ENSG00000140931 E005 0.5078857 1.568336e-02 0.169174701 0.44082850 16 66604183 66604275 93 + 0.000 0.233 12.705
ENSG00000140931 E006 0.5078857 1.568336e-02 0.169174701 0.44082850 16 66604276 66604309 34 + 0.000 0.233 12.705
ENSG00000140931 E007 1.6501329 7.867668e-03 0.002182338 0.02725219 16 66604310 66604340 31 + 0.000 0.520 14.475
ENSG00000140931 E008 4.8460712 3.010635e-03 0.623539567 0.83786823 16 66604341 66604449 109 + 0.703 0.764 0.248
ENSG00000140931 E009 1.3505735 9.749703e-03 0.459314720 0.73104747 16 66604450 66604482 33 + 0.429 0.315 -0.659
ENSG00000140931 E010 1.8591233 3.592272e-02 0.937763995 0.98211507 16 66604483 66604555 73 + 0.429 0.444 0.078
ENSG00000140931 E011 7.5708629 2.447428e-03 0.003048988 0.03492124 16 66604704 66604730 27 + 1.083 0.789 -1.108
ENSG00000140931 E012 11.2634840 3.973944e-02 0.021237698 0.13179542 16 66604731 66604731 1 + 1.217 0.963 -0.921
ENSG00000140931 E013 16.9547852 1.574494e-02 0.024946842 0.14519417 16 66604732 66604740 9 + 1.347 1.156 -0.670
ENSG00000140931 E014 110.1991063 1.400166e-04 0.033182322 0.17314329 16 66604741 66604894 154 + 2.060 1.998 -0.209
ENSG00000140931 E015 61.1825449 2.306771e-04 0.012216332 0.09153826 16 66604895 66604929 35 + 1.831 1.732 -0.332
ENSG00000140931 E016 55.7403683 2.655957e-04 0.008415781 0.07153613 16 66604930 66604952 23 + 1.797 1.689 -0.366
ENSG00000140931 E017 1.7391298 1.776618e-02 0.643243860 0.84869546 16 66605273 66605426 154 + 0.371 0.444 0.400
ENSG00000140931 E018 1.2508795 9.921389e-03 0.316646131 0.60953401 16 66605521 66605567 47 + 0.224 0.384 1.078
ENSG00000140931 E019 192.8106349 9.120446e-05 0.406269158 0.68898814 16 66608309 66608464 156 + 2.273 2.255 -0.060
ENSG00000140931 E020 1.4859471 7.717520e-02 0.932010325 0.98018924 16 66609372 66609434 63 + 0.371 0.384 0.078
ENSG00000140931 E021 152.7645891 2.246032e-04 0.175276418 0.44932546 16 66609435 66609530 96 + 2.136 2.171 0.119
ENSG00000140931 E022 4.2349297 3.273115e-03 0.317733171 0.61048501 16 66609759 66609882 124 + 0.606 0.736 0.552
ENSG00000140931 E023 173.5682864 1.062316e-04 0.743014829 0.89839494 16 66609883 66610003 121 + 2.210 2.218 0.027
ENSG00000140931 E024 0.7443456 1.390079e-02 0.951410936 0.98777913 16 66610004 66610060 57 + 0.224 0.233 0.078
ENSG00000140931 E025 3.1157841 5.959362e-03 0.261151398 0.55387100 16 66610850 66611061 212 + 0.480 0.641 0.741
ENSG00000140931 E026 60.3362410 5.148554e-04 0.915210819 0.97341656 16 66612609 66612611 3 + 1.758 1.763 0.016
ENSG00000140931 E027 475.6744277 6.382499e-05 0.769277730 0.91085212 16 66612612 66613061 450 + 2.648 2.653 0.014
ENSG00000140931 E028 781.2424545 6.418045e-05 0.005405826 0.05237252 16 66613062 66613917 856 + 2.848 2.875 0.089

Help

Please Click HERE to learn more details about the results from DEXseq.