ENSG00000140943

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000343411 ENSG00000140943 No_inf pgKDN_inf MBTPS1 protein_coding protein_coding 41.22498 40.13518 41.55791 1.095433 1.199222 0.05024352 20.980259 14.549871 25.8523465 0.8632375 0.8512695 0.8288556 0.50854167 0.364575 0.624950 0.260375 0.008374976 0.008374976 FALSE TRUE
ENST00000562886 ENSG00000140943 No_inf pgKDN_inf MBTPS1 protein_coding retained_intron 41.22498 40.13518 41.55791 1.095433 1.199222 0.05024352 1.551495 2.822021 0.7801014 0.3883495 0.2738864 -1.8417225 0.03816667 0.069850 0.019350 -0.050500 0.185130316 0.008374976 FALSE FALSE
ENST00000564049 ENSG00000140943 No_inf pgKDN_inf MBTPS1 protein_coding retained_intron 41.22498 40.13518 41.55791 1.095433 1.199222 0.05024352 1.699246 2.870983 0.7266384 0.3634663 0.4250639 -1.9675326 0.04146667 0.072100 0.016675 -0.055425 0.245794976 0.008374976   FALSE
MSTRG.11616.2 ENSG00000140943 No_inf pgKDN_inf MBTPS1 protein_coding   41.22498 40.13518 41.55791 1.095433 1.199222 0.05024352 13.214831 14.569282 11.0910167 0.8580781 1.7589639 -0.3932279 0.32029167 0.363050 0.264550 -0.098500 0.546210681 0.008374976 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000140943 E001 0.0000000       16 84053761 84053762 2 -      
ENSG00000140943 E002 1.2003289 1.606189e-02 7.156562e-02 2.710928e-01 16 84053763 84053765 3 - 0.459 0.179 -1.882
ENSG00000140943 E003 1.8073100 7.473870e-03 9.643662e-02 3.234958e-01 16 84053766 84053773 8 - 0.554 0.305 -1.341
ENSG00000140943 E004 217.0250969 8.981154e-05 7.788275e-07 3.727177e-05 16 84053774 84054645 872 - 2.291 2.381 0.301
ENSG00000140943 E005 38.5816906 3.762349e-04 2.581219e-02 1.484648e-01 16 84056005 84056135 131 - 1.542 1.647 0.358
ENSG00000140943 E006 4.8067288 2.922341e-03 1.704305e-01 4.426342e-01 16 84056136 84058044 1909 - 0.678 0.837 0.642
ENSG00000140943 E007 14.5752696 3.641657e-03 6.064708e-03 5.694547e-02 16 84059302 84059302 1 - 1.072 1.287 0.765
ENSG00000140943 E008 36.5479541 1.379048e-02 3.921668e-02 1.917634e-01 16 84059303 84059428 126 - 1.502 1.637 0.460
ENSG00000140943 E009 0.4985390 2.605141e-02 2.832585e-01   16 84059429 84059474 46 - 0.092 0.247 1.703
ENSG00000140943 E010 9.1457035 1.277645e-02 3.314835e-08 2.135989e-06 16 84059475 84060681 1207 - 0.608 1.212 2.325
ENSG00000140943 E011 39.6234735 3.733908e-04 8.607914e-02 3.039029e-01 16 84060682 84060813 132 - 1.568 1.647 0.270
ENSG00000140943 E012 15.5088203 8.978274e-04 1.320835e-12 1.692112e-10 16 84060814 84061631 818 - 0.852 1.415 2.033
ENSG00000140943 E013 38.1762010 3.703490e-04 7.682249e-01 9.103050e-01 16 84063305 84063445 141 - 1.586 1.599 0.044
ENSG00000140943 E014 26.4723646 5.232981e-04 4.210621e-01 7.002319e-01 16 84065690 84065767 78 - 1.462 1.415 -0.162
ENSG00000140943 E015 34.1153313 4.566407e-04 1.159385e-01 3.591009e-01 16 84066489 84066613 125 - 1.584 1.503 -0.276
ENSG00000140943 E016 35.1255011 1.481270e-03 5.058782e-02 2.222964e-01 16 84067667 84067823 157 - 1.505 1.605 0.341
ENSG00000140943 E017 23.7949521 6.133829e-04 5.304739e-01 7.815800e-01 16 84068339 84068454 116 - 1.413 1.375 -0.134
ENSG00000140943 E018 27.4812302 6.005747e-04 3.049532e-02 1.643256e-01 16 84069866 84070018 153 - 1.512 1.388 -0.424
ENSG00000140943 E019 13.1164651 1.022744e-03 4.699441e-01 7.379167e-01 16 84070019 84070038 20 - 1.121 1.177 0.199
ENSG00000140943 E020 9.3361756 1.466226e-03 2.947674e-01 5.880110e-01 16 84070588 84070597 10 - 0.965 1.059 0.347
ENSG00000140943 E021 25.8613689 5.380269e-04 4.121671e-01 6.935635e-01 16 84070598 84070714 117 - 1.405 1.452 0.159
ENSG00000140943 E022 16.3362277 8.357853e-03 4.259036e-01 7.048154e-01 16 84070715 84070763 49 - 1.270 1.205 -0.228
ENSG00000140943 E023 11.1869207 1.632676e-03 1.442473e-01 4.043973e-01 16 84070764 84070776 13 - 1.144 1.019 -0.454
ENSG00000140943 E024 0.0000000       16 84071804 84072137 334 -      
ENSG00000140943 E025 26.8482430 6.054074e-04 3.914421e-01 6.765673e-01 16 84074597 84074741 145 - 1.469 1.419 -0.171
ENSG00000140943 E026 4.5737213 5.727791e-02 1.698440e-01 4.419106e-01 16 84074742 84075433 692 - 0.632 0.837 0.835
ENSG00000140943 E027 2.2492116 2.243489e-02 1.309384e-02 9.583432e-02 16 84075523 84075656 134 - 0.288 0.660 1.926
ENSG00000140943 E028 0.1176306 1.177269e-02 5.850185e-01   16 84081522 84081746 225 - 0.092 0.000 -11.606
ENSG00000140943 E029 29.8138138 5.913868e-03 6.550591e-02 2.577888e-01 16 84081747 84081908 162 - 1.542 1.427 -0.394
ENSG00000140943 E030 0.0000000       16 84081909 84082169 261 -      
ENSG00000140943 E031 18.0543471 8.063457e-04 1.431977e-03 1.971719e-02 16 84084983 84085053 71 - 1.376 1.154 -0.781
ENSG00000140943 E032 21.3999723 6.024037e-04 4.457722e-02 2.063573e-01 16 84085054 84085134 81 - 1.409 1.281 -0.446
ENSG00000140943 E033 23.1943417 6.202275e-04 5.639906e-01 8.032286e-01 16 84087358 84087460 103 - 1.401 1.365 -0.125
ENSG00000140943 E034 22.5870155 7.026765e-04 5.986644e-01 8.240431e-01 16 84090875 84090942 68 - 1.389 1.356 -0.116
ENSG00000140943 E035 27.2165295 5.414638e-04 9.612320e-03 7.834929e-02 16 84091732 84091848 117 - 1.518 1.370 -0.510
ENSG00000140943 E036 20.4832841 2.553732e-02 3.683098e-01 6.567804e-01 16 84093188 84093297 110 - 1.368 1.293 -0.261
ENSG00000140943 E037 15.9935598 9.424773e-04 5.160269e-01 7.718260e-01 16 84093711 84093821 111 - 1.253 1.205 -0.169
ENSG00000140943 E038 25.8511201 1.835770e-02 2.380618e-02 1.412167e-01 16 84095602 84095805 204 - 1.508 1.330 -0.615
ENSG00000140943 E039 36.5087791 4.802166e-03 4.798760e-04 8.458051e-03 16 84099053 84099310 258 - 1.662 1.463 -0.678
ENSG00000140943 E040 18.5037817 8.897408e-04 2.940205e-04 5.712429e-03 16 84101621 84101734 114 - 1.397 1.146 -0.882
ENSG00000140943 E041 12.4976460 4.414186e-03 5.022287e-02 2.214635e-01 16 84101735 84101800 66 - 1.205 1.039 -0.596
ENSG00000140943 E042 11.6367163 2.675408e-02 1.126980e-01 3.531405e-01 16 84101801 84101897 97 - 1.179 1.008 -0.618
ENSG00000140943 E043 12.1547924 1.673766e-02 2.517087e-01 5.428960e-01 16 84101898 84101969 72 - 1.172 1.059 -0.406
ENSG00000140943 E044 12.3086716 1.244105e-03 5.060094e-01 7.647568e-01 16 84101970 84102065 96 - 1.151 1.096 -0.197
ENSG00000140943 E045 6.6342073 3.730580e-02 3.469226e-02 1.779959e-01 16 84102066 84102107 42 - 0.997 0.727 -1.042
ENSG00000140943 E046 0.1268540 1.234512e-02 4.946055e-01   16 84109456 84109583 128 - 0.000 0.099 10.877
ENSG00000140943 E047 0.1265070 1.229407e-02 4.946732e-01   16 84110713 84110825 113 - 0.000 0.099 10.877
ENSG00000140943 E048 0.1265070 1.229407e-02 4.946732e-01   16 84110826 84110853 28 - 0.000 0.099 10.877
ENSG00000140943 E049 12.1054979 1.944024e-03 1.044726e-02 8.265548e-02 16 84116735 84116942 208 - 1.211 0.997 -0.775

Help

Please Click HERE to learn more details about the results from DEXseq.