ENSG00000140995

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000561959 ENSG00000140995 No_inf pgKDN_inf DEF8 protein_coding protein_coding 26.41478 33.69467 23.20421 2.340229 0.3198084 -0.5379404 0.7056288 0.4534561 1.663430 0.4534561 0.9617904 1.8523040 0.02861667 0.013575 0.072275 0.058700 0.74374458 0.01589983 FALSE TRUE
ENST00000562163 ENSG00000140995 No_inf pgKDN_inf DEF8 protein_coding protein_coding_CDS_not_defined 26.41478 33.69467 23.20421 2.340229 0.3198084 -0.5379404 1.7812410 3.5082623 1.094293 2.0363207 0.6362693 -1.6717404 0.05755000 0.097325 0.046950 -0.050375 0.99306410 0.01589983 FALSE FALSE
ENST00000563594 ENSG00000140995 No_inf pgKDN_inf DEF8 protein_coding protein_coding 26.41478 33.69467 23.20421 2.340229 0.3198084 -0.5379404 3.2821692 6.2341382 1.127586 0.7850507 0.6908549 -2.4565271 0.12417500 0.187150 0.049150 -0.138000 0.21454955 0.01589983 FALSE TRUE
ENST00000568760 ENSG00000140995 No_inf pgKDN_inf DEF8 protein_coding retained_intron 26.41478 33.69467 23.20421 2.340229 0.3198084 -0.5379404 2.2112464 3.7154512 1.288033 0.7562688 0.4777959 -1.5210876 0.07736667 0.110550 0.055325 -0.055225 0.69086434 0.01589983   FALSE
ENST00000610455 ENSG00000140995 No_inf pgKDN_inf DEF8 protein_coding protein_coding 26.41478 33.69467 23.20421 2.340229 0.3198084 -0.5379404 11.5462015 10.7660404 13.314551 0.3775140 0.6784888 0.3062597 0.46507500 0.323075 0.574450 0.251375 0.01589983 0.01589983 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000140995 E001 0.1187032 0.0118369609 2.366654e-01   16 89948697 89948730 34 + 0.132 0.000 -11.371
ENSG00000140995 E002 0.1187032 0.0118369609 2.366654e-01   16 89948731 89948754 24 + 0.132 0.000 -13.770
ENSG00000140995 E003 0.4909846 0.0159203931 4.578347e-01   16 89948755 89948774 20 + 0.233 0.126 -1.071
ENSG00000140995 E004 0.3722815 0.0167676537 1.000000e+00   16 89948775 89948778 4 + 0.132 0.126 -0.071
ENSG00000140995 E005 1.5861213 0.0503953870 1.302924e-01 3.829806e-01 16 89948779 89948790 12 + 0.542 0.304 -1.294
ENSG00000140995 E006 2.0775138 0.0076606012 7.894755e-02 2.880696e-01 16 89948791 89948794 4 + 0.623 0.371 -1.241
ENSG00000140995 E007 2.8194074 0.0168660457 1.315922e-01 3.848648e-01 16 89948795 89948802 8 + 0.690 0.481 -0.946
ENSG00000140995 E008 3.8172729 0.0063909016 2.562734e-01 5.483121e-01 16 89948803 89948814 12 + 0.749 0.606 -0.602
ENSG00000140995 E009 0.5075387 0.0357714464 2.122274e-01 4.974352e-01 16 89949417 89949419 3 + 0.000 0.224 13.244
ENSG00000140995 E010 2.7470599 0.0052446146 3.392457e-01 6.309267e-01 16 89949420 89949513 94 + 0.443 0.588 0.694
ENSG00000140995 E011 0.3806233 0.0158735398 3.531697e-01   16 89949514 89949564 51 + 0.000 0.178 12.912
ENSG00000140995 E012 0.3806233 0.0158735398 3.531697e-01   16 89949565 89949638 74 + 0.000 0.178 12.912
ENSG00000140995 E013 1.0164006 0.0139956827 3.167588e-02 1.681279e-01 16 89950067 89950306 240 + 0.000 0.371 14.120
ENSG00000140995 E014 0.1272623 0.0123901786 1.000000e+00   16 89950307 89950328 22 + 0.000 0.068 11.464
ENSG00000140995 E015 0.2459004 0.0164831381 5.564242e-01   16 89952558 89952561 4 + 0.132 0.068 -1.071
ENSG00000140995 E016 0.8809870 0.1949613347 3.780736e-01 6.652159e-01 16 89952562 89952682 121 + 0.132 0.304 1.514
ENSG00000140995 E017 0.4979743 0.0318409404 8.113123e-01   16 89954172 89954242 71 + 0.132 0.178 0.514
ENSG00000140995 E018 7.2729249 0.0019503197 1.627397e-01 4.312984e-01 16 89954243 89954288 46 + 0.978 0.839 -0.527
ENSG00000140995 E019 13.5176345 0.0010774574 3.018259e-03 3.465761e-02 16 89954289 89954376 88 + 1.273 1.047 -0.808
ENSG00000140995 E020 17.1538638 0.0009630065 7.748924e-06 2.740528e-04 16 89955169 89955266 98 + 1.412 1.108 -1.071
ENSG00000140995 E021 0.0000000       16 89956530 89956648 119 +      
ENSG00000140995 E022 0.0000000       16 89956694 89956887 194 +      
ENSG00000140995 E023 2.1304507 0.0066436794 1.837771e-01 4.607585e-01 16 89957253 89957472 220 + 0.315 0.527 1.151
ENSG00000140995 E024 1.1046084 0.0109827156 4.410014e-01 7.166453e-01 16 89957473 89957510 38 + 0.384 0.266 -0.749
ENSG00000140995 E025 10.0203262 0.0014328665 1.266249e-04 2.876744e-03 16 89957511 89957537 27 + 1.211 0.880 -1.212
ENSG00000140995 E026 7.5444061 0.0019228591 2.543004e-05 7.573405e-04 16 89957538 89957540 3 + 1.139 0.732 -1.541
ENSG00000140995 E027 19.7424662 0.0008745938 2.127191e-05 6.481803e-04 16 89957541 89957660 120 + 1.452 1.181 -0.946
ENSG00000140995 E028 0.2533610 0.0161133902 6.407947e-01   16 89958002 89958041 40 + 0.000 0.126 12.385
ENSG00000140995 E029 0.3720642 0.0167562653 1.000000e+00   16 89958351 89958431 81 + 0.132 0.126 -0.071
ENSG00000140995 E030 0.1268540 0.0124352418 1.000000e+00   16 89958432 89958533 102 + 0.000 0.068 11.464
ENSG00000140995 E031 22.9630493 0.0007793874 8.428309e-01 9.437670e-01 16 89959014 89959155 142 + 1.334 1.351 0.059
ENSG00000140995 E032 9.6048312 0.0015066263 5.615870e-02 2.362977e-01 16 89959156 89959366 211 + 1.104 0.934 -0.624
ENSG00000140995 E033 5.1205446 0.0028189840 1.546351e-01 4.200710e-01 16 89960931 89960972 42 + 0.623 0.806 0.759
ENSG00000140995 E034 8.2137933 0.0017881009 4.019936e-01 6.851343e-01 16 89960973 89961095 123 + 0.868 0.959 0.344
ENSG00000140995 E035 7.5740163 0.0019109326 8.845704e-01 9.611270e-01 16 89961737 89961864 128 + 0.889 0.908 0.073
ENSG00000140995 E036 2.9760603 0.0047077908 8.911506e-01 9.637844e-01 16 89962012 89962052 41 + 0.584 0.568 -0.071
ENSG00000140995 E037 4.1986489 0.0033082436 4.468913e-01 7.211216e-01 16 89962053 89962125 73 + 0.749 0.658 -0.379
ENSG00000140995 E038 0.4882806 0.4432709364 5.556280e-01   16 89962126 89962234 109 + 0.233 0.126 -1.069
ENSG00000140995 E039 4.8690141 0.0030701490 2.193787e-01 5.060377e-01 16 89963363 89963443 81 + 0.623 0.783 0.666
ENSG00000140995 E040 2.5230260 0.0172942320 2.327594e-02 1.392992e-01 16 89963798 89963839 42 + 0.233 0.606 2.099
ENSG00000140995 E041 1.1350992 0.3899399481 3.578571e-01 6.473474e-01 16 89963840 89963886 47 + 0.132 0.371 1.930
ENSG00000140995 E042 0.8774307 0.1236452429 3.463940e-01 6.371901e-01 16 89963887 89964169 283 + 0.132 0.304 1.514
ENSG00000140995 E043 2.8911901 0.0076803387 3.701673e-02 1.852567e-01 16 89964170 89964220 51 + 0.315 0.641 1.666
ENSG00000140995 E044 5.7428427 0.0033834848 2.300726e-01 5.186206e-01 16 89964221 89964310 90 + 0.690 0.839 0.599
ENSG00000140995 E045 0.3814089 0.6017049975 6.676084e-01   16 89964311 89964465 155 + 0.000 0.178 12.428
ENSG00000140995 E046 8.5899450 0.0130178012 6.098081e-01 8.302287e-01 16 89964466 89964575 110 + 0.908 0.967 0.221
ENSG00000140995 E047 126.7335749 0.0001791320 3.437105e-14 5.420375e-12 16 89965861 89968275 2415 + 1.932 2.121 0.636

Help

Please Click HERE to learn more details about the results from DEXseq.