ENSG00000141258

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000268989 ENSG00000141258 No_inf pgKDN_inf SGSM2 protein_coding protein_coding 6.488118 9.544142 3.602903 0.3635961 0.7035192 -1.402968 1.4121149 2.9082354 0.2147576 0.7317719 0.2147576 -3.6986544 0.19576667 0.312700 0.088625 -0.224075 0.33353924 0.02403984 FALSE TRUE
ENST00000426855 ENSG00000141258 No_inf pgKDN_inf SGSM2 protein_coding protein_coding 6.488118 9.544142 3.602903 0.3635961 0.7035192 -1.402968 0.9921569 0.8874838 1.0949792 0.8874838 0.1584785 0.3000614 0.20405833 0.086300 0.341875 0.255575 0.15614622 0.02403984 FALSE TRUE
ENST00000572841 ENSG00000141258 No_inf pgKDN_inf SGSM2 protein_coding retained_intron 6.488118 9.544142 3.602903 0.3635961 0.7035192 -1.402968 0.5394366 0.9086824 0.7096273 0.6122896 0.4139364 -0.3523163 0.08385833 0.103000 0.148575 0.045575 0.84979375 0.02403984 FALSE TRUE
ENST00000572875 ENSG00000141258 No_inf pgKDN_inf SGSM2 protein_coding nonsense_mediated_decay 6.488118 9.544142 3.602903 0.3635961 0.7035192 -1.402968 0.1553782 0.0000000 0.4661346 0.0000000 0.4661346 5.5732975 0.03082500 0.000000 0.092475 0.092475 0.66627017 0.02403984   FALSE
ENST00000572925 ENSG00000141258 No_inf pgKDN_inf SGSM2 protein_coding protein_coding 6.488118 9.544142 3.602903 0.3635961 0.7035192 -1.402968 1.6400691 2.7770139 0.0000000 1.0884970 0.0000000 -8.1225764 0.20765000 0.282925 0.000000 -0.282925 0.14525661 0.02403984   FALSE
ENST00000573717 ENSG00000141258 No_inf pgKDN_inf SGSM2 protein_coding retained_intron 6.488118 9.544142 3.602903 0.3635961 0.7035192 -1.402968 0.4151573 0.8924092 0.1120935 0.3483043 0.1120935 -2.8857952 0.04955833 0.092625 0.022250 -0.070375 0.77074287 0.02403984 FALSE FALSE
ENST00000574250 ENSG00000141258 No_inf pgKDN_inf SGSM2 protein_coding retained_intron 6.488118 9.544142 3.602903 0.3635961 0.7035192 -1.402968 0.7144694 0.0000000 0.8444847 0.0000000 0.3786931 6.4169827 0.14940000 0.000000 0.262025 0.262025 0.02403984 0.02403984 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000141258 E001 0.0000000       17 2337498 2337500 3 +      
ENSG00000141258 E002 0.0000000       17 2337501 2337505 5 +      
ENSG00000141258 E003 0.1271363 0.0129290413 1.0000000000   17 2337506 2337513 8 + 0.000 0.057 9.327
ENSG00000141258 E004 0.9726572 0.0132957110 0.0193789390 0.12442663 17 2337514 2337621 108 + 0.499 0.151 -2.370
ENSG00000141258 E005 1.2274965 0.3401699150 0.2298142119 0.51831256 17 2337622 2337745 124 + 0.500 0.229 -1.636
ENSG00000141258 E006 0.7624103 0.0977391433 0.2298158211 0.51831256 17 2343545 2343620 76 + 0.000 0.263 13.620
ENSG00000141258 E007 2.2494326 0.0064844483 0.9088399928 0.97110263 17 2361637 2361776 140 + 0.435 0.469 0.175
ENSG00000141258 E008 1.2336612 0.0124862702 0.2467657480 0.53736329 17 2361777 2361799 23 + 0.435 0.263 -1.048
ENSG00000141258 E009 1.4901696 0.0917051584 0.4473738158 0.72150805 17 2362109 2362184 76 + 0.435 0.325 -0.633
ENSG00000141258 E010 1.7510844 0.0125118493 0.8668290686 0.95412430 17 2362185 2362270 86 + 0.360 0.403 0.242
ENSG00000141258 E011 1.7600555 0.0084852076 0.3992596889 0.68304718 17 2362838 2362905 68 + 0.270 0.426 0.952
ENSG00000141258 E012 1.1248454 0.0110668475 0.9377554281 0.98211507 17 2362906 2362988 83 + 0.270 0.295 0.175
ENSG00000141258 E013 1.7505853 0.0224650766 0.8728104499 0.95654540 17 2362989 2363134 146 + 0.360 0.403 0.242
ENSG00000141258 E014 0.7442221 0.0138601059 0.5788981455 0.81180879 17 2363465 2363509 45 + 0.270 0.192 -0.633
ENSG00000141258 E015 1.3784274 0.0098186129 0.6780863923 0.86677445 17 2363510 2363561 52 + 0.270 0.352 0.537
ENSG00000141258 E016 1.5126769 0.0575383527 0.2035429360 0.48617736 17 2363562 2363599 38 + 0.156 0.403 1.827
ENSG00000141258 E017 0.0000000       17 2363845 2363979 135 +      
ENSG00000141258 E018 0.1265070 0.0127323594 1.0000000000   17 2363980 2363999 20 + 0.000 0.057 11.537
ENSG00000141258 E019 0.1265070 0.0127323594 1.0000000000   17 2364000 2364058 59 + 0.000 0.057 11.537
ENSG00000141258 E020 2.8942463 0.0413724860 0.2558191665 0.54790386 17 2364059 2364183 125 + 0.360 0.577 1.104
ENSG00000141258 E021 0.2539903 0.0163759489 1.0000000000   17 2364184 2364595 412 + 0.000 0.107 12.397
ENSG00000141258 E022 1.6521468 0.0528033071 0.0258650843 0.14864224 17 2364596 2364663 68 + 0.000 0.448 14.454
ENSG00000141258 E023 0.0000000       17 2364664 2364896 233 +      
ENSG00000141258 E024 3.5082385 0.0109537818 0.4824527589 0.74734246 17 2364897 2365057 161 + 0.499 0.623 0.569
ENSG00000141258 E025 2.6039289 0.0257217369 0.3228514594 0.61568569 17 2365215 2365285 71 + 0.604 0.469 -0.633
ENSG00000141258 E026 3.3467705 0.1316180196 0.2988889002 0.59183870 17 2365286 2365341 56 + 0.688 0.544 -0.632
ENSG00000141258 E027 0.2543986 0.0163089370 1.0000000000   17 2366528 2367270 743 + 0.000 0.107 12.397
ENSG00000141258 E028 2.2560133 0.1778090520 0.5589204814 0.80030730 17 2367271 2367405 135 + 0.360 0.489 0.691
ENSG00000141258 E029 2.0852249 0.0178800003 0.0349261717 0.17873690 17 2371262 2371415 154 + 0.648 0.352 -1.463
ENSG00000141258 E030 0.0000000       17 2371416 2371820 405 +      
ENSG00000141258 E031 0.1272623 0.0124864891 1.0000000000   17 2371863 2372189 327 + 0.000 0.057 11.537
ENSG00000141258 E032 2.7462437 0.0534802181 0.9892026460 1.00000000 17 2372190 2372254 65 + 0.499 0.527 0.133
ENSG00000141258 E033 0.8798884 0.0960333835 0.6182816012 0.83487056 17 2372255 2372342 88 + 0.156 0.263 0.952
ENSG00000141258 E034 2.8703916 0.1370594098 0.9274187501 0.97839377 17 2372343 2372488 146 + 0.499 0.544 0.215
ENSG00000141258 E035 1.1427505 0.2076557988 0.1236671880 0.37239857 17 2372489 2372580 92 + 0.000 0.352 14.009
ENSG00000141258 E036 2.8509952 0.0179211428 0.2305984020 0.51903406 17 2372581 2372952 372 + 0.648 0.489 -0.726
ENSG00000141258 E037 2.6289562 0.0345382743 0.6623586453 0.85925800 17 2372953 2373081 129 + 0.435 0.527 0.455
ENSG00000141258 E038 0.6336374 0.0526776318 0.2909992064 0.58452521 17 2373082 2373330 249 + 0.000 0.229 13.440
ENSG00000141258 E039 4.1190315 0.0036470506 0.9013226656 0.96817965 17 2373331 2373513 183 + 0.648 0.651 0.011
ENSG00000141258 E040 4.9251631 0.0918786569 0.0282498853 0.15720484 17 2373514 2374580 1067 + 0.361 0.778 1.951
ENSG00000141258 E041 5.3871863 0.0027341902 0.4460265718 0.72045514 17 2375492 2375875 384 + 0.648 0.768 0.496
ENSG00000141258 E042 3.7615718 0.0043747939 0.3648346129 0.65332708 17 2376137 2376261 125 + 0.499 0.651 0.689
ENSG00000141258 E043 0.1272623 0.0124864891 1.0000000000   17 2376360 2376732 373 + 0.000 0.057 11.537
ENSG00000141258 E044 0.0000000       17 2376733 2376815 83 +      
ENSG00000141258 E045 2.6420723 0.1586285523 0.4709975788 0.73856036 17 2376959 2377068 110 + 0.360 0.544 0.953
ENSG00000141258 E046 3.2592206 0.0225649290 0.6232509414 0.83776334 17 2377857 2377912 56 + 0.499 0.593 0.438
ENSG00000141258 E047 2.3766313 0.0067503884 0.8062875583 0.92836158 17 2377913 2377953 41 + 0.435 0.489 0.274
ENSG00000141258 E048 2.8765245 0.0177996014 0.8603461605 0.95157920 17 2379036 2379167 132 + 0.499 0.544 0.215
ENSG00000141258 E049 0.0000000       17 2379168 2379203 36 +      
ENSG00000141258 E050 0.0000000       17 2379204 2379431 228 +      
ENSG00000141258 E051 2.4833526 0.0417296576 0.5054637326 0.76429619 17 2379432 2379493 62 + 0.555 0.469 -0.410
ENSG00000141258 E052 17.2070233 0.0009132115 0.0006638134 0.01088348 17 2379494 2380264 771 + 1.345 1.131 -0.756
ENSG00000141258 E053 20.0057603 0.0011768731 0.4862780852 0.75000493 17 2380265 2381068 804 + 1.195 1.267 0.257

Help

Please Click HERE to learn more details about the results from DEXseq.