ENSG00000141295

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000290216 ENSG00000141295 No_inf pgKDN_inf SCRN2 protein_coding protein_coding 13.65743 21.96814 9.642136 1.203259 0.802113 -1.187149 2.0230481 0.000000 4.5813429 0.0000000 1.5797065 8.842772 0.19870833 0.000000 0.476725 0.476725 0.003087844 0.003087844 FALSE TRUE
ENST00000407215 ENSG00000141295 No_inf pgKDN_inf SCRN2 protein_coding protein_coding 13.65743 21.96814 9.642136 1.203259 0.802113 -1.187149 3.7259806 7.767966 1.6357516 0.9215360 1.2521799 -2.240646 0.25066667 0.353675 0.178250 -0.175425 0.456272364 0.003087844 FALSE TRUE
ENST00000578840 ENSG00000141295 No_inf pgKDN_inf SCRN2 protein_coding retained_intron 13.65743 21.96814 9.642136 1.203259 0.802113 -1.187149 0.1810258 0.000000 0.5430775 0.0000000 0.5430775 5.789410 0.01923333 0.000000 0.057700 0.057700 0.767296398 0.003087844 FALSE TRUE
ENST00000580428 ENSG00000141295 No_inf pgKDN_inf SCRN2 protein_coding retained_intron 13.65743 21.96814 9.642136 1.203259 0.802113 -1.187149 0.9410670 2.066351 0.5653878 0.7228672 0.3289938 -1.851443 0.05584167 0.090300 0.053125 -0.037175 0.848529378 0.003087844 FALSE TRUE
ENST00000582656 ENSG00000141295 No_inf pgKDN_inf SCRN2 protein_coding retained_intron 13.65743 21.96814 9.642136 1.203259 0.802113 -1.187149 1.8053025 3.396604 1.1437174 0.3487542 0.4703093 -1.562044 0.11537500 0.154550 0.109625 -0.044925 0.830994716 0.003087844   FALSE
ENST00000584567 ENSG00000141295 No_inf pgKDN_inf SCRN2 protein_coding protein_coding 13.65743 21.96814 9.642136 1.203259 0.802113 -1.187149 0.4500634 1.350190 0.0000000 0.8718682 0.0000000 -7.087665 0.02035000 0.061050 0.000000 -0.061050 0.698611122 0.003087844 FALSE TRUE
MSTRG.12839.1 ENSG00000141295 No_inf pgKDN_inf SCRN2 protein_coding   13.65743 21.96814 9.642136 1.203259 0.802113 -1.187149 0.9261845 1.207941 0.2965814 0.4916391 0.2965814 -1.990102 0.06740833 0.054500 0.025250 -0.029250 0.791112110 0.003087844 FALSE TRUE
MSTRG.12839.4 ENSG00000141295 No_inf pgKDN_inf SCRN2 protein_coding   13.65743 21.96814 9.642136 1.203259 0.802113 -1.187149 2.0551459 3.770599 0.5521677 0.7763218 0.3742504 -2.749542 0.15380833 0.176925 0.058000 -0.118925 0.446492029 0.003087844 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000141295 E001 0.0000000       17 47837692 47837701 10 -      
ENSG00000141295 E002 0.0000000       17 47837702 47837706 5 -      
ENSG00000141295 E003 0.0000000       17 47837707 47837707 1 -      
ENSG00000141295 E004 0.0000000       17 47837708 47837719 12 -      
ENSG00000141295 E005 0.1271363 0.0123855986 1.0000000000   17 47837720 47837729 10 - 0.000 0.061 8.950
ENSG00000141295 E006 9.8611329 0.0014955170 0.4611756865 0.73207704 17 47837730 47837969 240 - 0.930 1.004 0.279
ENSG00000141295 E007 5.6587047 0.0026879134 0.0203776608 0.12843120 17 47837970 47838002 33 - 0.528 0.840 1.321
ENSG00000141295 E008 10.5762701 0.0129401910 0.0009403647 0.01431392 17 47838003 47838269 267 - 0.694 1.087 1.508
ENSG00000141295 E009 6.5788254 0.0070891838 0.6932693516 0.87469983 17 47838270 47838312 43 - 0.864 0.820 -0.170
ENSG00000141295 E010 6.0513966 0.0413746236 0.2500455463 0.54097542 17 47838313 47838335 23 - 0.909 0.756 -0.595
ENSG00000141295 E011 16.0746277 0.0010093618 0.5803788215 0.81277583 17 47838336 47838450 115 - 1.147 1.192 0.161
ENSG00000141295 E012 3.4007745 0.0041812895 0.0358091814 0.18153326 17 47838451 47838530 80 - 0.339 0.667 1.620
ENSG00000141295 E013 19.2945887 0.0008272355 0.0041814083 0.04379881 17 47838531 47838696 166 - 1.081 1.304 0.790
ENSG00000141295 E014 0.1265070 0.0123526367 1.0000000000   17 47838697 47838719 23 - 0.000 0.061 10.753
ENSG00000141295 E015 16.1793908 0.0131660131 0.8174025543 0.93360879 17 47838791 47838958 168 - 1.193 1.179 -0.050
ENSG00000141295 E016 4.4947779 0.0266601203 0.7515332605 0.90214885 17 47838959 47838960 2 - 0.658 0.707 0.205
ENSG00000141295 E017 7.6910906 0.0019118628 0.4191536386 0.69875916 17 47838961 47839006 46 - 0.949 0.868 -0.309
ENSG00000141295 E018 5.3147368 0.0027363071 0.1723840583 0.44514803 17 47839444 47839458 15 - 0.864 0.707 -0.625
ENSG00000141295 E019 11.5939819 0.0015511799 0.0122957696 0.09187587 17 47839459 47839643 185 - 1.193 0.984 -0.756
ENSG00000141295 E020 0.8695926 0.1138676362 0.9823867427 0.99866264 17 47839644 47839660 17 - 0.253 0.245 -0.058
ENSG00000141295 E021 0.4982540 0.0157930964 1.0000000000   17 47839661 47839673 13 - 0.145 0.163 0.205
ENSG00000141295 E022 4.8758067 0.0032188990 0.5149753133 0.77132602 17 47839674 47839858 185 - 0.658 0.744 0.357
ENSG00000141295 E023 2.3839034 0.0060816514 0.2229411570 0.51038280 17 47839859 47839901 43 - 0.339 0.535 1.035
ENSG00000141295 E024 5.7499964 0.0024165552 0.3550479681 0.64477447 17 47839902 47840190 289 - 0.694 0.810 0.468
ENSG00000141295 E025 14.4434971 0.0010953964 0.0048143408 0.04822746 17 47840191 47840372 182 - 1.282 1.071 -0.754
ENSG00000141295 E026 2.3624429 0.0640905397 0.8949054309 0.96529080 17 47840373 47840669 297 - 0.473 0.495 0.106
ENSG00000141295 E027 14.2109633 0.0010864039 0.0108789048 0.08500550 17 47840670 47840843 174 - 1.264 1.071 -0.689
ENSG00000141295 E028 0.8874067 0.0916720913 0.1014799246 0.33265191 17 47840844 47841173 330 - 0.000 0.314 13.274
ENSG00000141295 E029 0.2374063 0.3218212422 0.0829642416   17 47841185 47841207 23 - 0.253 0.000 -14.342
ENSG00000141295 E030 5.0794345 0.0033721158 0.3625593887 0.65183100 17 47841208 47841327 120 - 0.815 0.707 -0.432

Help

Please Click HERE to learn more details about the results from DEXseq.