ENSG00000141380

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000415083 ENSG00000141380 No_inf pgKDN_inf SS18 protein_coding protein_coding 40.62992 26.20153 34.92079 0.2997715 0.5889383 0.4142977 9.834497 6.428300 10.515965 0.3578120 1.1761282 0.7092009 0.2852083 0.245550 0.300475 0.054925 8.292346e-01 6.088545e-05 FALSE  
ENST00000542420 ENSG00000141380 No_inf pgKDN_inf SS18 protein_coding protein_coding 40.62992 26.20153 34.92079 0.2997715 0.5889383 0.4142977 0.992299 0.000000 2.772962 0.0000000 0.3234727 8.1204775 0.0268750 0.000000 0.079200 0.079200 6.088545e-05 6.088545e-05 FALSE  
ENST00000580958 ENSG00000141380 No_inf pgKDN_inf SS18 protein_coding retained_intron 40.62992 26.20153 34.92079 0.2997715 0.5889383 0.4142977 3.978827 3.739306 3.213344 0.7354452 0.4282651 -0.2180656 0.1194000 0.142325 0.092300 -0.050025 7.779457e-01 6.088545e-05    
ENST00000582092 ENSG00000141380 No_inf pgKDN_inf SS18 protein_coding protein_coding_CDS_not_defined 40.62992 26.20153 34.92079 0.2997715 0.5889383 0.4142977 9.209857 0.000000 0.000000 0.0000000 0.0000000 0.0000000 0.0643750 0.000000 0.000000 0.000000   6.088545e-05    
MSTRG.13768.2 ENSG00000141380 No_inf pgKDN_inf SS18 protein_coding   40.62992 26.20153 34.92079 0.2997715 0.5889383 0.4142977 14.824268 14.945649 16.571435 0.4353869 1.0390048 0.1488784 0.4528500 0.570375 0.475500 -0.094875 6.239105e-01 6.088545e-05 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000141380 E001 0.0000000       18 26016253 26016255 3 -      
ENSG00000141380 E002 141.8437445 0.0003071335 4.021062e-07 2.032539e-05 18 26016256 26017342 1087 - 2.096 2.213 0.392
ENSG00000141380 E003 104.7651042 0.0001618524 1.203785e-01 3.669942e-01 18 26017343 26017884 542 - 2.003 2.045 0.142
ENSG00000141380 E004 33.2416003 0.0004418984 7.093683e-01 8.824237e-01 18 26017885 26018006 122 - 1.541 1.522 -0.065
ENSG00000141380 E005 13.6375524 0.0010212278 7.277608e-01 8.913193e-01 18 26018007 26018013 7 - 1.176 1.149 -0.096
ENSG00000141380 E006 29.8531616 0.0004969288 9.164121e-01 9.737077e-01 18 26018014 26018119 106 - 1.490 1.484 -0.019
ENSG00000141380 E007 38.9069517 0.0003566521 1.849322e-01 4.624706e-01 18 26018120 26018349 230 - 1.627 1.564 -0.213
ENSG00000141380 E008 11.5069046 0.0023153648 8.313285e-02 2.971251e-01 18 26018350 26018380 31 - 1.157 1.008 -0.538
ENSG00000141380 E009 0.0000000       18 26023613 26023632 20 -      
ENSG00000141380 E010 17.6142637 0.0030213495 1.808146e-01 4.565670e-01 18 26032399 26032532 134 - 1.309 1.213 -0.339
ENSG00000141380 E011 14.2474117 0.0047367334 7.237348e-01 8.890337e-01 18 26035005 26035090 86 - 1.194 1.166 -0.101
ENSG00000141380 E012 11.4330335 0.0012353472 5.363470e-01 7.857060e-01 18 26035091 26035127 37 - 1.116 1.064 -0.188
ENSG00000141380 E013 9.7239932 0.0133733453 5.386331e-02 2.309120e-01 18 26035128 26035614 487 - 0.931 1.122 0.702
ENSG00000141380 E014 9.2129994 0.0014704318 5.589652e-02 2.355843e-01 18 26035831 26035923 93 - 0.920 1.094 0.642
ENSG00000141380 E015 19.6791724 0.0008500175 2.804679e-01 5.737873e-01 18 26038555 26038659 105 - 1.280 1.351 0.246
ENSG00000141380 E016 20.5676630 0.0007295734 1.293227e-01 3.814750e-01 18 26039289 26039409 121 - 1.285 1.382 0.337
ENSG00000141380 E017 11.1894244 0.0244067212 7.594592e-01 9.055884e-01 18 26039410 26039456 47 - 1.101 1.064 -0.135
ENSG00000141380 E018 11.1504624 0.0018461496 1.365193e-01 3.930305e-01 18 26052624 26052681 58 - 1.137 1.008 -0.467
ENSG00000141380 E019 7.7841960 0.0020655704 6.345535e-01 8.437872e-01 18 26052682 26052704 23 - 0.963 0.916 -0.176
ENSG00000141380 E020 10.0597958 0.0030881518 1.767656e-01 4.510847e-01 18 26052705 26052742 38 - 1.094 0.971 -0.449
ENSG00000141380 E021 9.5652972 0.0018619172 1.438057e-01 4.037911e-01 18 26052743 26052770 28 - 1.078 0.944 -0.493
ENSG00000141380 E022 10.8898710 0.0154597305 1.237566e-01 3.725538e-01 18 26052771 26052822 52 - 1.137 0.984 -0.557
ENSG00000141380 E023 7.2937494 0.0174603929 6.159903e-01 8.334366e-01 18 26052823 26052845 23 - 0.942 0.885 -0.213
ENSG00000141380 E024 7.1551837 0.0030960085 3.321939e-01 6.243787e-01 18 26057589 26057611 23 - 0.952 0.853 -0.378
ENSG00000141380 E025 12.8877881 0.0018669491 5.324411e-01 7.828547e-01 18 26057612 26057694 83 - 1.163 1.113 -0.179
ENSG00000141380 E026 6.4626254 0.0106786023 9.774877e-01 9.966128e-01 18 26057695 26057698 4 - 0.873 0.869 -0.012
ENSG00000141380 E027 7.1729888 0.0020648190 4.768147e-01 7.431809e-01 18 26057699 26057718 20 - 0.942 0.869 -0.275
ENSG00000141380 E028 6.4647130 0.0021673622 9.763863e-01 9.960072e-01 18 26057719 26057731 13 - 0.872 0.869 -0.012
ENSG00000141380 E029 6.2940880 0.0025488810 1.114091e-01 3.505146e-01 18 26057732 26057742 11 - 0.931 0.758 -0.670
ENSG00000141380 E030 0.0000000       18 26064832 26064871 40 -      
ENSG00000141380 E031 0.1186381 0.0117866032 6.944685e-01   18 26068260 26068493 234 - 0.085 0.000 -10.306
ENSG00000141380 E032 0.0000000       18 26068494 26068557 64 -      
ENSG00000141380 E033 8.2421921 0.0017330939 1.665143e-01 4.368510e-01 18 26078076 26078102 27 - 1.020 0.885 -0.503
ENSG00000141380 E034 11.7414302 0.0015283843 5.635705e-02 2.367368e-01 18 26078103 26078160 58 - 1.169 1.008 -0.584
ENSG00000141380 E035 0.8532634 0.0137039441 9.685333e-01 9.936412e-01 18 26078161 26078386 226 - 0.270 0.264 -0.043
ENSG00000141380 E036 1.1136968 0.4142380974 4.739242e-01 7.407895e-01 18 26079011 26079125 115 - 0.216 0.426 1.370
ENSG00000141380 E037 0.1186381 0.0117866032 6.944685e-01   18 26079126 26079146 21 - 0.085 0.000 -10.306
ENSG00000141380 E038 0.6052820 0.0189018412 8.724019e-01 9.564008e-01 18 26080305 26080370 66 - 0.216 0.192 -0.213
ENSG00000141380 E039 0.7137877 0.0388674464 1.750769e-01 4.489419e-01 18 26080371 26080423 53 - 0.317 0.107 -1.950
ENSG00000141380 E040 0.2539903 0.0159660579 1.662471e-01   18 26081225 26081365 141 - 0.000 0.192 10.997
ENSG00000141380 E041 0.0000000       18 26082363 26082382 20 -      
ENSG00000141380 E042 0.1187032 0.0117578921 6.945089e-01   18 26082383 26082528 146 - 0.085 0.000 -10.307
ENSG00000141380 E043 0.3621152 0.1311855264 7.795220e-01   18 26084052 26084175 124 - 0.155 0.107 -0.628
ENSG00000141380 E044 0.0000000       18 26085923 26086027 105 -      
ENSG00000141380 E045 10.7168148 0.0014952678 1.270730e-03 1.800159e-02 18 26087501 26087577 77 - 1.176 0.885 -1.066
ENSG00000141380 E046 0.0000000       18 26089758 26089824 67 -      
ENSG00000141380 E047 0.0000000       18 26089825 26090135 311 -      
ENSG00000141380 E048 7.8166759 0.0073889636 2.395172e-03 2.918030e-02 18 26090501 26090901 401 - 1.062 0.737 -1.243
ENSG00000141380 E049 0.4797798 0.0157394380 4.586186e-01   18 26091004 26091095 92 - 0.216 0.107 -1.213
ENSG00000141380 E050 0.8347517 0.0125362092 1.003073e-01 3.307841e-01 18 26091096 26091217 122 - 0.360 0.107 -2.213

Help

Please Click HERE to learn more details about the results from DEXseq.