ENSG00000141480

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000269260 ENSG00000141480 No_inf pgKDN_inf ARRB2 protein_coding protein_coding 104.4666 134.4654 85.00602 2.531821 0.1008885 -0.6615354 43.648960 44.942734 38.771789 5.146212 5.750379 -0.2130295 0.43145833 0.334725 0.456275 0.121550 0.54358237 0.02590704 FALSE  
ENST00000571206 ENSG00000141480 No_inf pgKDN_inf ARRB2 protein_coding protein_coding 104.4666 134.4654 85.00602 2.531821 0.1008885 -0.6615354 7.212621 13.732522 4.250268 1.079649 1.760138 -1.6896307 0.06385833 0.102150 0.050025 -0.052125 0.37800286 0.02590704 FALSE  
ENST00000573886 ENSG00000141480 No_inf pgKDN_inf ARRB2 protein_coding retained_intron 104.4666 134.4654 85.00602 2.531821 0.1008885 -0.6615354 4.487977 9.257799 1.022989 1.298601 0.505923 -3.1654024 0.03825833 0.068375 0.012050 -0.056325 0.02590704 0.02590704 FALSE  
ENST00000574954 ENSG00000141480 No_inf pgKDN_inf ARRB2 protein_coding protein_coding 104.4666 134.4654 85.00602 2.531821 0.1008885 -0.6615354 18.698378 23.490011 21.519772 3.974973 3.498304 -0.1263284 0.18135833 0.174375 0.253050 0.078675 0.63968520 0.02590704 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000141480 E001 1.1171948 0.0157865932 7.049480e-01 0.8801488017 17 4710523 4710595 73 + 0.280 0.340 0.389
ENSG00000141480 E002 1.7344655 0.0078995389 7.729312e-01 0.9125991562 17 4710596 4710629 34 + 0.400 0.444 0.237
ENSG00000141480 E003 1.3627186 0.0105850867 8.328526e-01 0.9397219349 17 4710630 4710631 2 + 0.344 0.378 0.196
ENSG00000141480 E004 1.3627186 0.0105850867 8.328526e-01 0.9397219349 17 4710632 4710633 2 + 0.344 0.378 0.196
ENSG00000141480 E005 2.9687873 0.0053306344 8.439215e-01 0.9441853758 17 4710634 4710642 9 + 0.571 0.599 0.126
ENSG00000141480 E006 6.7511204 0.0020945866 2.476969e-01 0.5384637921 17 4710643 4710654 12 + 0.948 0.829 -0.454
ENSG00000141480 E007 7.8669608 0.0017265167 3.499170e-01 0.6401698645 17 4710655 4710660 6 + 0.990 0.899 -0.340
ENSG00000141480 E008 16.9136223 0.0008079366 3.260865e-02 0.1711311764 17 4710661 4710681 21 + 1.328 1.178 -0.527
ENSG00000141480 E009 19.8623622 0.0006672135 2.666583e-02 0.1514214945 17 4710682 4710690 9 + 1.391 1.246 -0.504
ENSG00000141480 E010 18.9995343 0.0006959534 2.597883e-02 0.1490576655 17 4710691 4710692 2 + 1.375 1.226 -0.518
ENSG00000141480 E011 19.1165383 0.0007016605 2.056172e-02 0.1291609321 17 4710693 4710696 4 + 1.380 1.226 -0.537
ENSG00000141480 E012 19.4790344 0.0006951763 1.538499e-02 0.1069572008 17 4710697 4710698 2 + 1.391 1.232 -0.557
ENSG00000141480 E013 22.9510480 0.0006053329 5.269974e-02 0.2280944983 17 4710699 4710723 25 + 1.436 1.318 -0.410
ENSG00000141480 E014 26.5307006 0.0005154886 6.008301e-02 0.2459222015 17 4710724 4710744 21 + 1.491 1.383 -0.370
ENSG00000141480 E015 7.5177256 0.0020520747 4.661255e-04 0.0082779103 17 4714551 4715012 462 + 0.636 1.030 1.544
ENSG00000141480 E016 20.5552445 0.0007639752 2.283178e-01 0.5168559915 17 4715013 4715043 31 + 1.268 1.350 0.286
ENSG00000141480 E017 3.2645138 0.0043635139 7.874525e-03 0.0684000427 17 4715151 4715199 49 + 0.344 0.729 1.848
ENSG00000141480 E018 5.4194169 0.0028520132 9.441591e-06 0.0003245524 17 4715200 4715336 137 + 0.344 0.941 2.674
ENSG00000141480 E019 15.6513318 0.0180809375 4.983361e-05 0.0013253087 17 4715589 4715972 384 + 0.917 1.322 1.462
ENSG00000141480 E020 43.1817643 0.0003878971 9.628258e-02 0.3231302449 17 4715973 4716033 61 + 1.677 1.602 -0.256
ENSG00000141480 E021 44.6666523 0.0003185870 8.303121e-01 0.9384986746 17 4716147 4716191 45 + 1.652 1.643 -0.030
ENSG00000141480 E022 2.8559788 0.0060979315 3.721397e-01 0.6600126642 17 4716192 4716411 220 + 0.494 0.620 0.581
ENSG00000141480 E023 98.4407057 0.0001699317 6.182317e-01 0.8348449531 17 4716412 4716608 197 + 1.993 1.979 -0.047
ENSG00000141480 E024 1.9866034 0.0069292920 4.982067e-01 0.7586977104 17 4716609 4716671 63 + 0.400 0.502 0.526
ENSG00000141480 E025 4.6097062 0.0101693538 1.247420e-01 0.3743718952 17 4716672 4717062 391 + 0.605 0.803 0.822
ENSG00000141480 E026 54.7147345 0.0002584956 6.950018e-01 0.8753851498 17 4717217 4717276 60 + 1.722 1.739 0.058
ENSG00000141480 E027 0.8808615 0.0123353855 1.501791e-01 0.4126845131 17 4717277 4717379 103 + 0.115 0.340 1.974
ENSG00000141480 E028 4.5959827 0.0030147263 2.205002e-01 0.5074440037 17 4717436 4717684 249 + 0.636 0.789 0.630
ENSG00000141480 E029 58.4148370 0.0002737822 6.456265e-01 0.8500444046 17 4717685 4717752 68 + 1.749 1.768 0.066
ENSG00000141480 E030 92.2604830 0.0001888514 4.873601e-01 0.7509012968 17 4717888 4718023 136 + 1.942 1.965 0.078
ENSG00000141480 E031 9.6464100 0.0016798046 6.480260e-05 0.0016456859 17 4718024 4718260 237 + 0.719 1.130 1.559
ENSG00000141480 E032 78.2798876 0.0002132523 1.083557e-02 0.0847455784 17 4718261 4718345 85 + 1.828 1.918 0.304
ENSG00000141480 E033 1.2341664 0.0146499316 9.749394e-01 0.9954113626 17 4718346 4718370 25 + 0.344 0.340 -0.026
ENSG00000141480 E034 87.8264363 0.0007099077 4.109160e-01 0.6926381738 17 4718612 4718684 73 + 1.917 1.946 0.097
ENSG00000141480 E035 48.3675959 0.0016815809 9.318826e-01 0.9801504779 17 4719283 4719289 7 + 1.677 1.682 0.017
ENSG00000141480 E036 112.9260097 0.0003410568 4.490520e-01 0.7229354571 17 4719290 4719420 131 + 2.056 2.036 -0.069
ENSG00000141480 E037 94.5402681 0.0028965889 1.013307e-01 0.3323707248 17 4720216 4720299 84 + 2.004 1.943 -0.203
ENSG00000141480 E038 3.3572831 0.0043755078 2.910054e-01 0.5845252124 17 4720300 4720392 93 + 0.534 0.678 0.637
ENSG00000141480 E039 81.6596834 0.0001939337 1.114295e-02 0.0863319507 17 4720393 4720472 80 + 1.954 1.871 -0.279
ENSG00000141480 E040 4.1583010 0.0042442827 2.227588e-01 0.5101500019 17 4720550 4720585 36 + 0.788 0.640 -0.611
ENSG00000141480 E041 60.0010707 0.0006655961 2.889715e-01 0.5825594306 17 4720586 4720640 55 + 1.797 1.756 -0.139
ENSG00000141480 E042 12.3127947 0.0462152110 8.560835e-02 0.3028002456 17 4720641 4720945 305 + 0.976 1.178 0.732
ENSG00000141480 E043 214.7503140 0.0000925225 2.666876e-02 0.1514214945 17 4720946 4721501 556 + 2.292 2.337 0.152

Help

Please Click HERE to learn more details about the results from DEXseq.