ENSG00000141506

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000269300 ENSG00000141506 No_inf pgKDN_inf PIK3R5 protein_coding nonsense_mediated_decay 19.29939 7.821312 21.26228 0.3607338 1.190319 1.441649 1.9846603 1.3591486 0.0000000 1.3591486 0.0000000 -7.0971352 0.11339167 0.175075 0.000000 -0.175075 0.79393992 0.03237439 FALSE  
ENST00000447110 ENSG00000141506 No_inf pgKDN_inf PIK3R5 protein_coding protein_coding 19.29939 7.821312 21.26228 0.3607338 1.190319 1.441649 3.4919032 0.0000000 3.7177406 0.0000000 3.7177406 8.5421577 0.13770000 0.000000 0.175000 0.175000 1.00000000 0.03237439 FALSE  
ENST00000583810 ENSG00000141506 No_inf pgKDN_inf PIK3R5 protein_coding retained_intron 19.29939 7.821312 21.26228 0.3607338 1.190319 1.441649 1.7991988 1.5973781 0.9102477 0.1495924 0.2971319 -0.8046153 0.11705833 0.205500 0.043050 -0.162450 0.05483318 0.03237439 FALSE  
ENST00000585260 ENSG00000141506 No_inf pgKDN_inf PIK3R5 protein_coding protein_coding 19.29939 7.821312 21.26228 0.3607338 1.190319 1.441649 0.7274774 0.8153325 0.1709500 0.0957303 0.1709500 -2.1893842 0.04999167 0.103925 0.007300 -0.096625 0.03237439 0.03237439    
ENST00000611902 ENSG00000141506 No_inf pgKDN_inf PIK3R5 protein_coding protein_coding 19.29939 7.821312 21.26228 0.3607338 1.190319 1.441649 3.1552086 0.5018585 3.5845716 0.5018585 2.1890994 2.8120028 0.14427500 0.071125 0.182000 0.110875 0.84887737 0.03237439 FALSE  
ENST00000616147 ENSG00000141506 No_inf pgKDN_inf PIK3R5 protein_coding protein_coding 19.29939 7.821312 21.26228 0.3607338 1.190319 1.441649 1.9975412 0.8388290 3.4384239 0.8388290 2.0030392 2.0223913 0.11059167 0.109375 0.166975 0.057600 0.85209968 0.03237439 FALSE  
ENST00000623421 ENSG00000141506 No_inf pgKDN_inf PIK3R5 protein_coding protein_coding 19.29939 7.821312 21.26228 0.3607338 1.190319 1.441649 1.1996765 0.5086952 3.0903343 0.5086952 3.0903343 2.5794650 0.06524167 0.057825 0.137900 0.080075 0.92454559 0.03237439 FALSE  
MSTRG.12040.1 ENSG00000141506 No_inf pgKDN_inf PIK3R5 protein_coding   19.29939 7.821312 21.26228 0.3607338 1.190319 1.441649 3.4391427 1.7877491 5.1881574 0.6372876 1.3808253 1.5318086 0.19620000 0.228150 0.235075 0.006925 0.98544294 0.03237439 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000141506 E001 0.9614448 0.0871291179 9.413563e-01 9.834598e-01 17 8878795 8878910 116 - 0.261 0.273 0.089
ENSG00000141506 E002 0.6065379 0.1712371954 4.585963e-01 7.304569e-01 17 8878911 8878915 5 - 0.149 0.273 1.090
ENSG00000141506 E003 0.4895339 0.4050846113 3.361809e-01   17 8878916 8878918 3 - 0.105 0.273 1.675
ENSG00000141506 E004 116.2653191 0.0001629358 1.544228e-01 4.198327e-01 17 8878919 8880095 1177 - 1.999 2.037 0.130
ENSG00000141506 E005 30.7233205 0.0004758814 6.319211e-01 8.422179e-01 17 8880096 8880463 368 - 1.449 1.421 -0.098
ENSG00000141506 E006 9.8194638 0.0013774470 3.401772e-01 6.318870e-01 17 8880464 8880577 114 - 1.002 0.903 -0.371
ENSG00000141506 E007 7.0217201 0.0020121967 6.986807e-02 2.673886e-01 17 8880578 8880638 61 - 0.793 0.989 0.748
ENSG00000141506 E008 3.6483986 0.0043515785 5.275557e-02 2.282638e-01 17 8880639 8880640 2 - 0.540 0.796 1.089
ENSG00000141506 E009 4.3767855 0.0039834983 4.776267e-02 2.149021e-01 17 8880641 8880650 10 - 0.604 0.852 1.021
ENSG00000141506 E010 13.9278519 0.0010583850 8.143919e-03 6.993061e-02 17 8880651 8880786 136 - 1.052 1.267 0.767
ENSG00000141506 E011 0.8790336 0.0124836938 6.074757e-04 1.016556e-02 17 8880787 8880904 118 - 0.056 0.559 4.259
ENSG00000141506 E012 14.5999341 0.0009664761 1.362132e-01 3.925262e-01 17 8880905 8881017 113 - 1.102 1.224 0.434
ENSG00000141506 E013 10.2823645 0.0013767395 1.450407e-01 4.054088e-01 17 8881630 8881712 83 - 1.031 0.878 -0.569
ENSG00000141506 E014 0.2457744 0.0163585742 3.635429e-01   17 8881713 8881787 75 - 0.056 0.158 1.674
ENSG00000141506 E015 9.9027049 0.0030823834 3.474712e-02 1.781418e-01 17 8881788 8881881 94 - 1.031 0.796 -0.891
ENSG00000141506 E016 4.5820430 0.0032651715 1.562133e-07 8.685784e-06 17 8881882 8882508 627 - 0.444 1.060 2.558
ENSG00000141506 E017 6.6494275 0.0021437743 3.680038e-03 4.008870e-02 17 8884707 8884783 77 - 0.902 0.503 -1.677
ENSG00000141506 E018 0.0000000       17 8884920 8885086 167 -      
ENSG00000141506 E019 6.6724649 0.0023499201 3.226026e-02 1.699477e-01 17 8886229 8886322 94 - 0.887 0.609 -1.134
ENSG00000141506 E020 9.5022412 0.0018554540 7.688829e-01 9.106268e-01 17 8886477 8886602 126 - 0.958 0.989 0.113
ENSG00000141506 E021 2.5401711 0.0054733689 3.329968e-01 6.250416e-01 17 8886603 8886605 3 - 0.465 0.609 0.674
ENSG00000141506 E022 11.7740454 0.0023958868 8.854557e-01 9.614690e-01 17 8887096 8887221 126 - 1.047 1.060 0.049
ENSG00000141506 E023 0.6073281 0.0147282873 4.257469e-01 7.047738e-01 17 8887222 8887270 49 - 0.150 0.273 1.089
ENSG00000141506 E024 0.3634701 0.0164681487 6.636775e-01   17 8887427 8887520 94 - 0.105 0.158 0.674
ENSG00000141506 E025 13.2976235 0.0010875280 4.237314e-01 7.029476e-01 17 8887521 8887683 163 - 1.116 1.044 -0.262
ENSG00000141506 E026 21.4612082 0.0008804125 4.997271e-01 7.599256e-01 17 8888171 8888563 393 - 1.305 1.256 -0.170
ENSG00000141506 E027 7.3143826 0.0084728405 6.472827e-01 8.509163e-01 17 8888564 8888637 74 - 0.880 0.825 -0.211
ENSG00000141506 E028 8.2123688 0.0031199307 1.026897e-02 8.169176e-02 17 8888638 8888740 103 - 0.971 0.653 -1.257
ENSG00000141506 E029 7.2606811 0.0155542805 4.946348e-02 2.192982e-01 17 8888741 8888891 151 - 0.917 0.653 -1.054
ENSG00000141506 E030 0.0000000       17 8888892 8888953 62 -      
ENSG00000141506 E031 4.4483841 0.0178691369 6.749162e-01 8.653085e-01 17 8889139 8889222 84 - 0.672 0.730 0.241
ENSG00000141506 E032 6.2281564 0.0074218834 6.510690e-01 8.530243e-01 17 8889973 8890126 154 - 0.821 0.764 -0.224
ENSG00000141506 E033 5.7485453 0.0945017932 6.991772e-01 8.774327e-01 17 8890738 8890818 81 - 0.793 0.730 -0.252
ENSG00000141506 E034 5.9938842 0.0514192911 7.861361e-01 9.175839e-01 17 8890819 8890912 94 - 0.802 0.764 -0.152
ENSG00000141506 E035 3.8154660 0.0037536838 2.535970e-01 5.451593e-01 17 8893586 8893655 70 - 0.672 0.503 -0.759
ENSG00000141506 E036 0.0000000       17 8893779 8893908 130 -      
ENSG00000141506 E037 8.3921844 0.0019768748 6.245523e-01 8.384956e-01 17 8904777 8904915 139 - 0.931 0.878 -0.201
ENSG00000141506 E038 5.7561497 0.0026526393 6.137288e-01 8.320808e-01 17 8905669 8905737 69 - 0.793 0.730 -0.252
ENSG00000141506 E039 4.9031757 0.0359535949 5.446157e-01 7.910510e-01 17 8909074 8909143 70 - 0.742 0.653 -0.371
ENSG00000141506 E040 4.0422995 0.0150476112 8.385097e-02 2.987454e-01 17 8909144 8909174 31 - 0.708 0.439 -1.233
ENSG00000141506 E041 6.6925606 0.0186205536 3.181983e-01 6.109652e-01 17 8911392 8911507 116 - 0.864 0.730 -0.528
ENSG00000141506 E042 0.6063545 0.0158701739 4.258530e-01 7.047980e-01 17 8911508 8911988 481 - 0.150 0.273 1.089
ENSG00000141506 E043 0.0000000       17 8912464 8912517 54 -      
ENSG00000141506 E044 0.2373413 0.0158310535 1.000000e+00   17 8915700 8916847 1148 - 0.105 0.000 -8.653
ENSG00000141506 E045 4.7773918 0.0032162343 3.303374e-01 6.228533e-01 17 8965596 8965899 304 - 0.742 0.609 -0.563

Help

Please Click HERE to learn more details about the results from DEXseq.