ENSG00000141524

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000322914 ENSG00000141524 No_inf pgKDN_inf TMC6 protein_coding protein_coding 222.1164 268.0674 195.7681 11.51401 3.271876 -0.4534305 34.474459 19.49446 44.591008 6.864368 6.811970 1.19327240 0.16503333 0.073625 0.228700 0.155075 5.807304e-01 1.736343e-09 FALSE  
ENST00000587480 ENSG00000141524 No_inf pgKDN_inf TMC6 protein_coding protein_coding_CDS_not_defined 222.1164 268.0674 195.7681 11.51401 3.271876 -0.4534305 7.665158 19.08401 0.000000 9.134863 0.000000 -10.89890465 0.02973333 0.070200 0.000000 -0.070200 1.736343e-09 1.736343e-09    
ENST00000589933 ENSG00000141524 No_inf pgKDN_inf TMC6 protein_coding retained_intron 222.1164 268.0674 195.7681 11.51401 3.271876 -0.4534305 18.784163 30.41001 11.635461 4.511908 2.054017 -1.38525264 0.08096667 0.112925 0.059800 -0.053125 2.382286e-01 1.736343e-09 FALSE  
ENST00000698544 ENSG00000141524 No_inf pgKDN_inf TMC6 protein_coding protein_coding_CDS_not_defined 222.1164 268.0674 195.7681 11.51401 3.271876 -0.4534305 73.275464 76.29052 73.338618 7.836023 4.887722 -0.05692303 0.33450833 0.282875 0.373925 0.091050 2.098140e-01 1.736343e-09    
ENST00000698545 ENSG00000141524 No_inf pgKDN_inf TMC6 protein_coding retained_intron 222.1164 268.0674 195.7681 11.51401 3.271876 -0.4534305 9.291355 20.41511 2.864421 1.862769 0.978450 -2.82900024 0.03792500 0.076425 0.014600 -0.061825 1.112101e-03 1.736343e-09 FALSE  
ENST00000698548 ENSG00000141524 No_inf pgKDN_inf TMC6 protein_coding protein_coding 222.1164 268.0674 195.7681 11.51401 3.271876 -0.4534305 16.134988 19.83524 11.675300 4.462843 1.988372 -0.76409793 0.07262500 0.074625 0.059850 -0.014775 8.531673e-01 1.736343e-09 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000141524 E001 0.0000000       17 78107397 78107397 1 -      
ENSG00000141524 E002 0.0000000       17 78107398 78107472 75 -      
ENSG00000141524 E003 0.0000000       17 78107473 78107840 368 -      
ENSG00000141524 E004 16.4362599 2.467854e-03 6.231836e-10 5.514322e-08 17 78107841 78109050 1210 - 0.847 1.379 1.926
ENSG00000141524 E005 324.8253771 7.387525e-05 4.384536e-127 4.729511e-123 17 78109051 78112917 3867 - 2.184 2.636 1.507
ENSG00000141524 E006 3.3625977 7.156775e-02 2.796863e-01 5.729261e-01 17 78112918 78112918 1 - 0.519 0.696 0.785
ENSG00000141524 E007 5.0990433 1.525477e-01 3.262190e-01 6.187331e-01 17 78112919 78112920 2 - 0.676 0.835 0.642
ENSG00000141524 E008 5.6981555 9.558962e-02 5.998708e-01 8.245853e-01 17 78112921 78112921 1 - 0.770 0.848 0.307
ENSG00000141524 E009 6.9240097 7.652546e-02 7.325768e-01 8.937031e-01 17 78112922 78112924 3 - 0.865 0.908 0.164
ENSG00000141524 E010 10.7406156 1.971133e-02 7.828831e-01 9.165585e-01 17 78112925 78112932 8 - 1.044 1.073 0.108
ENSG00000141524 E011 22.4865301 1.354765e-02 4.556763e-01 7.281088e-01 17 78112933 78112952 20 - 1.325 1.387 0.215
ENSG00000141524 E012 103.7786018 2.480358e-04 1.076808e-01 3.440559e-01 17 78112953 78113075 123 - 2.039 1.993 -0.154
ENSG00000141524 E013 167.4363774 1.082027e-04 3.466665e-02 1.779322e-01 17 78113076 78113211 136 - 2.245 2.199 -0.157
ENSG00000141524 E014 148.9315550 1.064454e-04 1.207490e-01 3.675797e-01 17 78113548 78113621 74 - 2.189 2.153 -0.120
ENSG00000141524 E015 79.3820058 1.886104e-04 9.172574e-02 3.144958e-01 17 78113622 78113624 3 - 1.929 1.874 -0.185
ENSG00000141524 E016 29.2835871 2.029522e-03 3.044499e-19 7.709014e-17 17 78113625 78115115 1491 - 1.008 1.633 2.188
ENSG00000141524 E017 107.1224066 2.604919e-04 2.284038e-03 2.822807e-02 17 78117269 78117315 47 - 2.076 1.988 -0.294
ENSG00000141524 E018 77.4347400 1.334285e-03 1.132611e-03 1.647862e-02 17 78117316 78117347 32 - 1.953 1.835 -0.399
ENSG00000141524 E019 175.5226185 5.250857e-04 6.165701e-04 1.024148e-02 17 78117468 78117644 177 - 2.285 2.204 -0.269
ENSG00000141524 E020 157.7043955 1.269456e-04 3.926369e-02 1.919376e-01 17 78117802 78117935 134 - 2.220 2.173 -0.158
ENSG00000141524 E021 4.7549297 6.439919e-03 8.115479e-03 6.978639e-02 17 78117936 78117948 13 - 0.518 0.861 1.444
ENSG00000141524 E022 15.9563117 5.634595e-03 2.086973e-04 4.335855e-03 17 78117949 78118172 224 - 1.008 1.323 1.122
ENSG00000141524 E023 122.2573579 2.124721e-04 2.571913e-02 1.481191e-01 17 78118971 78119046 76 - 2.117 2.058 -0.198
ENSG00000141524 E024 5.8862255 2.841610e-03 1.055217e-03 1.560518e-02 17 78119062 78119296 235 - 0.555 0.951 1.615
ENSG00000141524 E025 129.9974608 1.255197e-04 2.237118e-02 1.360410e-01 17 78119297 78119392 96 - 2.143 2.085 -0.195
ENSG00000141524 E026 6.3048831 2.794718e-03 5.041459e-01 7.633736e-01 17 78120177 78120408 232 - 0.810 0.885 0.289
ENSG00000141524 E027 7.3986228 2.026105e-03 4.785961e-05 1.284848e-03 17 78120409 78120555 147 - 0.588 1.050 1.830
ENSG00000141524 E028 5.2836224 2.725204e-03 2.405504e-05 7.219725e-04 17 78120556 78120652 97 - 0.387 0.940 2.425
ENSG00000141524 E029 133.1150805 1.530440e-04 1.037213e-04 2.447116e-03 17 78120653 78120832 180 - 2.176 2.076 -0.332
ENSG00000141524 E030 5.4752347 3.205880e-03 4.694697e-02 2.128478e-01 17 78120833 78121012 180 - 0.648 0.885 0.952
ENSG00000141524 E031 128.4556154 1.187335e-03 1.633350e-03 2.184848e-02 17 78121013 78121164 152 - 2.156 2.065 -0.305
ENSG00000141524 E032 104.8232297 1.404934e-03 1.535423e-02 1.068260e-01 17 78121556 78121711 156 - 2.061 1.984 -0.260
ENSG00000141524 E033 1.3970575 1.373795e-01 5.093783e-03 5.032306e-02 17 78122560 78122604 45 - 0.000 0.518 13.542
ENSG00000141524 E034 89.9198088 7.823588e-04 3.684107e-01 6.568984e-01 17 78122605 78122749 145 - 1.967 1.939 -0.094
ENSG00000141524 E035 6.1622778 3.769687e-03 3.799353e-05 1.055715e-03 17 78122946 78123478 533 - 0.479 0.989 2.122
ENSG00000141524 E036 123.1997177 9.943205e-04 7.682906e-02 2.834267e-01 17 78123989 78124178 190 - 2.115 2.065 -0.168
ENSG00000141524 E037 41.8245724 2.809798e-03 4.570549e-01 7.291842e-01 17 78124179 78124179 1 - 1.644 1.609 -0.122
ENSG00000141524 E038 15.3755350 7.425313e-03 3.872138e-13 5.327548e-11 17 78124180 78124523 344 - 0.648 1.379 2.734
ENSG00000141524 E039 114.4599142 1.903478e-04 1.011319e-01 3.321226e-01 17 78124524 78124655 132 - 2.080 2.036 -0.148
ENSG00000141524 E040 93.3422640 3.142502e-04 3.945875e-02 1.925421e-01 17 78124656 78124781 126 - 2.003 1.940 -0.211
ENSG00000141524 E041 72.2944327 4.966632e-04 1.425555e-02 1.014800e-01 17 78124889 78124985 97 - 1.906 1.820 -0.291
ENSG00000141524 E042 3.7299156 4.277424e-02 2.293506e-01 5.180416e-01 17 78125080 78125157 78 - 0.555 0.731 0.759
ENSG00000141524 E043 66.8014934 2.356255e-04 3.856594e-02 1.899210e-01 17 78125158 78125263 106 - 1.866 1.792 -0.250
ENSG00000141524 E044 37.8959638 3.506346e-04 2.643707e-02 1.506770e-01 17 78125726 78125753 28 - 1.642 1.536 -0.360
ENSG00000141524 E045 73.5015834 2.175812e-04 1.917636e-04 4.043228e-03 17 78125754 78125884 131 - 1.936 1.807 -0.434
ENSG00000141524 E046 2.8935177 5.691487e-03 2.858535e-03 3.330573e-02 17 78125885 78125922 38 - 0.270 0.713 2.274
ENSG00000141524 E047 6.2750949 2.259541e-03 9.510608e-05 2.282800e-03 17 78125923 78126064 142 - 0.518 0.989 1.930
ENSG00000141524 E048 4.1085845 3.653210e-03 8.461232e-02 3.005454e-01 17 78126065 78126195 131 - 0.555 0.778 0.952
ENSG00000141524 E049 2.3564928 7.120406e-03 3.615344e-01 6.510235e-01 17 78126196 78126276 81 - 0.435 0.569 0.653
ENSG00000141524 E050 66.6780109 2.209892e-04 1.401747e-05 4.573612e-04 17 78126277 78126366 90 - 1.909 1.752 -0.532
ENSG00000141524 E051 53.9573011 1.035074e-03 1.113668e-02 8.630951e-02 17 78126524 78126596 73 - 1.792 1.686 -0.358
ENSG00000141524 E052 23.6825783 6.019696e-04 1.459552e-01 4.068610e-01 17 78126597 78126599 3 - 1.434 1.348 -0.298
ENSG00000141524 E053 35.4306578 3.835525e-04 2.634516e-02 1.504234e-01 17 78126600 78126648 49 - 1.615 1.506 -0.373
ENSG00000141524 E054 51.4136074 3.046234e-04 2.208939e-02 1.350605e-01 17 78126777 78126906 130 - 1.765 1.671 -0.318
ENSG00000141524 E055 11.5745959 3.359026e-03 7.453955e-01 8.992565e-01 17 78126907 78126974 68 - 1.107 1.081 -0.092
ENSG00000141524 E056 68.8062933 2.105914e-04 1.450353e-11 1.602937e-09 17 78126975 78128297 1323 - 1.658 1.924 0.898
ENSG00000141524 E057 14.0642336 1.294635e-03 2.924593e-02 1.605027e-01 17 78128612 78128658 47 - 1.261 1.096 -0.588
ENSG00000141524 E058 14.3423342 1.541678e-03 4.312650e-05 1.179506e-03 17 78128659 78128798 140 - 1.336 1.025 -1.109
ENSG00000141524 E059 0.1265070 1.227620e-02 7.466721e-01   17 78130637 78130683 47 - 0.000 0.082 10.950
ENSG00000141524 E060 0.2459655 1.638084e-02 7.997747e-01   17 78131001 78131397 397 - 0.110 0.082 -0.463
ENSG00000141524 E061 0.6356513 1.512591e-02 4.839832e-02 2.165518e-01 17 78132150 78132340 191 - 0.000 0.310 13.185
ENSG00000141524 E062 0.1272623 1.234776e-02 7.467091e-01   17 78132341 78132407 67 - 0.000 0.082 10.948

Help

Please Click HERE to learn more details about the results from DEXseq.