ENSG00000141959

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000349048 ENSG00000141959 No_inf pgKDN_inf PFKL protein_coding protein_coding 112.478 92.49851 111.242 1.860751 3.384615 0.2661739 87.581185 63.48377 96.669059 2.228207 1.594132 0.6065884 0.77613333 0.687300 0.871850 0.18455 0.007421132 0.007421132 FALSE TRUE
ENST00000467315 ENSG00000141959 No_inf pgKDN_inf PFKL protein_coding retained_intron 112.478 92.49851 111.242 1.860751 3.384615 0.2661739 8.810379 11.21404 4.950526 1.033605 2.884897 -1.1780265 0.07976667 0.120825 0.042575 -0.07825 0.363122250 0.007421132 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000141959 E001 0.5971582 0.0174729412 1.989282e-01 4.804283e-01 21 44300051 44300052 2 + 0.289 0.098 -1.896
ENSG00000141959 E002 2.6343626 0.0986862330 4.858034e-02 2.171001e-01 21 44300053 44300066 14 + 0.700 0.356 -1.660
ENSG00000141959 E003 12.4140505 0.0041316567 2.362332e-01 5.254188e-01 21 44300067 44300095 29 + 1.174 1.076 -0.352
ENSG00000141959 E004 14.2404354 0.0027029303 1.785703e-01 4.534409e-01 21 44300096 44300105 10 + 1.232 1.128 -0.369
ENSG00000141959 E005 33.0020790 0.0020334367 6.979854e-04 1.132866e-02 21 44300106 44300190 85 + 1.614 1.429 -0.633
ENSG00000141959 E006 0.9794510 0.2089596977 9.565467e-01 9.897057e-01 21 44304275 44304323 49 + 0.289 0.304 0.103
ENSG00000141959 E007 0.8580137 0.1995164327 7.142870e-01 8.849053e-01 21 44304324 44304455 132 + 0.232 0.304 0.520
ENSG00000141959 E008 1.1069952 0.0114662662 6.664350e-01 8.613391e-01 21 44305194 44305256 63 + 0.289 0.356 0.426
ENSG00000141959 E009 2.2238467 0.0276701037 3.022056e-01 5.953596e-01 21 44305257 44305417 161 + 0.424 0.579 0.756
ENSG00000141959 E010 0.3806233 0.0163939902 9.065555e-02   21 44305800 44305935 136 + 0.000 0.246 10.815
ENSG00000141959 E011 45.7273684 0.0003533170 3.172393e-03 3.597558e-02 21 44306681 44306754 74 + 1.730 1.600 -0.439
ENSG00000141959 E012 56.6747006 0.0033438830 5.104568e-01 7.680052e-01 21 44311006 44311083 78 + 1.775 1.747 -0.095
ENSG00000141959 E013 105.9360405 0.0001591111 7.117990e-02 2.703533e-01 21 44312105 44312294 190 + 2.054 2.003 -0.169
ENSG00000141959 E014 99.8255192 0.0001765073 5.550358e-02 2.346946e-01 21 44312978 44313143 166 + 2.030 1.975 -0.186
ENSG00000141959 E015 42.4509617 0.0003693927 1.315323e-01 3.847314e-01 21 44313638 44313682 45 + 1.670 1.603 -0.229
ENSG00000141959 E016 73.1086759 0.0016628261 1.442873e-01 4.044064e-01 21 44313913 44314021 109 + 1.896 1.842 -0.181
ENSG00000141959 E017 21.4320211 0.0006361833 3.818656e-06 1.488117e-04 21 44314022 44315526 1505 + 1.174 1.476 1.054
ENSG00000141959 E018 14.8224640 0.0008981326 1.656929e-08 1.134071e-06 21 44315527 44316243 717 + 0.920 1.368 1.609
ENSG00000141959 E019 66.9072695 0.0002216406 2.766192e-01 5.701090e-01 21 44316244 44316339 96 + 1.851 1.813 -0.128
ENSG00000141959 E020 68.5548730 0.0002215862 5.271661e-03 5.158233e-02 21 44316432 44316524 93 + 1.889 1.790 -0.335
ENSG00000141959 E021 82.4430841 0.0001927655 4.813266e-02 2.159364e-01 21 44318470 44318595 126 + 1.952 1.889 -0.213
ENSG00000141959 E022 64.7890284 0.0002363679 7.271155e-01 8.909727e-01 21 44319351 44319415 65 + 1.824 1.813 -0.038
ENSG00000141959 E023 11.7140312 0.0054051829 9.956115e-07 4.641081e-05 21 44319416 44319622 207 + 0.824 1.273 1.648
ENSG00000141959 E024 13.3067073 0.0010669656 2.431133e-06 1.003219e-04 21 44319623 44319840 218 + 0.920 1.307 1.398
ENSG00000141959 E025 3.2533735 0.0044943212 7.306050e-04 1.173800e-02 21 44319841 44319866 26 + 0.339 0.801 2.174
ENSG00000141959 E026 18.7709930 0.0007111140 2.564004e-08 1.692619e-06 21 44319867 44320083 217 + 1.056 1.450 1.386
ENSG00000141959 E027 63.9305476 0.0002361728 7.507663e-01 9.016993e-01 21 44320084 44320147 64 + 1.818 1.807 -0.034
ENSG00000141959 E028 4.4693033 0.0432897919 2.872542e-02 1.587488e-01 21 44320148 44320576 429 + 0.556 0.866 1.288
ENSG00000141959 E029 16.4243369 0.0239810267 2.823778e-05 8.236757e-04 21 44320577 44321728 1152 + 0.988 1.400 1.464
ENSG00000141959 E030 88.3999767 0.0008166216 8.738693e-01 9.569172e-01 21 44321729 44321875 147 + 1.953 1.950 -0.012
ENSG00000141959 E031 64.5852010 0.0002313389 8.654882e-01 9.536886e-01 21 44322133 44322203 71 + 1.813 1.821 0.028
ENSG00000141959 E032 70.3862107 0.0002176362 8.320828e-02 2.972614e-01 21 44322962 44323049 88 + 1.883 1.823 -0.202
ENSG00000141959 E033 117.5399056 0.0001377338 3.049851e-01 5.982348e-01 21 44323766 44323918 153 + 2.087 2.060 -0.088
ENSG00000141959 E034 1.6125530 0.1193449682 2.348840e-01 5.240601e-01 21 44324420 44324490 71 + 0.289 0.516 1.273
ENSG00000141959 E035 145.7034930 0.0020258914 4.683877e-01 7.365486e-01 21 44324491 44324655 165 + 2.176 2.156 -0.066
ENSG00000141959 E036 91.8781489 0.0002405152 9.309106e-01 9.798596e-01 21 44324856 44324917 62 + 1.966 1.970 0.016
ENSG00000141959 E037 8.3777238 0.0016179327 2.852484e-07 1.502401e-05 21 44324918 44325152 235 + 0.634 1.160 2.025
ENSG00000141959 E038 110.9991006 0.0001425054 1.714409e-01 4.439517e-01 21 44325153 44325264 112 + 2.028 2.069 0.136
ENSG00000141959 E039 21.0598548 0.0099244601 5.516310e-05 1.448217e-03 21 44325265 44325731 467 + 1.160 1.472 1.091
ENSG00000141959 E040 17.0584503 0.0073842600 2.885027e-07 1.516580e-05 21 44325732 44325960 229 + 0.999 1.417 1.485
ENSG00000141959 E041 111.8181707 0.0001648400 2.855170e-01 5.791737e-01 21 44325961 44326060 100 + 2.036 2.068 0.107
ENSG00000141959 E042 119.9806553 0.0001594728 9.557175e-01 9.892828e-01 21 44326159 44326264 106 + 2.083 2.083 0.001
ENSG00000141959 E043 278.8369788 0.0003295612 5.099346e-01 7.675568e-01 21 44326715 44327376 662 + 2.452 2.442 -0.034

Help

Please Click HERE to learn more details about the results from DEXseq.