ENSG00000142082

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000382743 ENSG00000142082 No_inf pgKDN_inf SIRT3 protein_coding protein_coding 8.872686 14.09824 6.745263 1.191133 0.7336229 -1.062454 1.3560846 1.5706953 1.0330230 0.3312275 0.2930642 -0.5997884 0.16898333 0.113425 0.149375 0.035950 0.88438268 0.04265951 FALSE TRUE
ENST00000524564 ENSG00000142082 No_inf pgKDN_inf SIRT3 protein_coding protein_coding 8.872686 14.09824 6.745263 1.191133 0.7336229 -1.062454 0.4564676 0.6448098 0.3537843 0.2772248 0.2055181 -0.8479925 0.05521667 0.044100 0.060350 0.016250 1.00000000 0.04265951 FALSE TRUE
ENST00000525319 ENSG00000142082 No_inf pgKDN_inf SIRT3 protein_coding protein_coding 8.872686 14.09824 6.745263 1.191133 0.7336229 -1.062454 1.8510981 2.9173080 1.3510609 1.1232557 0.7846620 -1.1048430 0.21932500 0.213350 0.224450 0.011100 0.90630626 0.04265951 FALSE TRUE
ENST00000525776 ENSG00000142082 No_inf pgKDN_inf SIRT3 protein_coding protein_coding 8.872686 14.09824 6.745263 1.191133 0.7336229 -1.062454 1.8358869 4.5216586 0.3107475 1.0532061 0.1802369 -3.8205293 0.15602500 0.308625 0.046950 -0.261675 0.04265951 0.04265951   FALSE
ENST00000528469 ENSG00000142082 No_inf pgKDN_inf SIRT3 protein_coding protein_coding 8.872686 14.09824 6.745263 1.191133 0.7336229 -1.062454 0.2855812 0.8567435 0.0000000 0.3712856 0.0000000 -6.4375332 0.01845833 0.055375 0.000000 -0.055375 0.33972761 0.04265951   FALSE
ENST00000532837 ENSG00000142082 No_inf pgKDN_inf SIRT3 protein_coding nonsense_mediated_decay 8.872686 14.09824 6.745263 1.191133 0.7336229 -1.062454 1.0107596 1.0410085 1.4633007 1.0410085 0.9199651 0.4872776 0.12030000 0.064400 0.213350 0.148950 0.72135561 0.04265951 FALSE TRUE
MSTRG.4180.17 ENSG00000142082 No_inf pgKDN_inf SIRT3 protein_coding   8.872686 14.09824 6.745263 1.191133 0.7336229 -1.062454 0.4613462 0.0000000 1.3840386 0.0000000 1.3840386 7.1231267 0.05405833 0.000000 0.162175 0.162175 0.78975492 0.04265951   FALSE
MSTRG.4180.2 ENSG00000142082 No_inf pgKDN_inf SIRT3 protein_coding   8.872686 14.09824 6.745263 1.191133 0.7336229 -1.062454 0.5785731 1.3278821 0.3692135 0.4430978 0.3692135 -1.8188689 0.06033333 0.100625 0.072775 -0.027850 0.72651715 0.04265951 TRUE TRUE
MSTRG.4180.3 ENSG00000142082 No_inf pgKDN_inf SIRT3 protein_coding   8.872686 14.09824 6.745263 1.191133 0.7336229 -1.062454 0.5079928 0.3442244 0.0000000 0.3442244 0.0000000 -5.1465918 0.08682500 0.028175 0.000000 -0.028175 0.98726020 0.04265951 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000142082 E001 0.6015365 0.016800972 2.641960e-02 0.1506770230 11 215030 215340 311 - 0.386 0.067 -3.097
ENSG00000142082 E002 6.9653829 0.003233013 6.656437e-01 0.8609310616 11 215341 216040 700 - 0.828 0.886 0.225
ENSG00000142082 E003 2.3661575 0.039703223 6.665489e-01 0.8613390790 11 216041 216144 104 - 0.446 0.524 0.388
ENSG00000142082 E004 2.8572609 0.005832177 9.391751e-01 0.9825895142 11 216145 216178 34 - 0.545 0.566 0.096
ENSG00000142082 E005 3.1047996 0.008077801 9.300757e-01 0.9794977915 11 216179 216205 27 - 0.587 0.585 -0.009
ENSG00000142082 E006 9.5771796 0.002302434 6.072764e-01 0.8290533252 11 216206 216390 185 - 0.948 1.009 0.225
ENSG00000142082 E007 9.6439500 0.001552437 2.457306e-01 0.5363293037 11 216391 216524 134 - 1.056 0.964 -0.340
ENSG00000142082 E008 7.7823383 0.002610715 2.354620e-01 0.5247936407 11 216525 216610 86 - 0.982 0.877 -0.396
ENSG00000142082 E009 8.1648938 0.002238115 3.632184e-01 0.6521897073 11 216611 216718 108 - 0.982 0.905 -0.290
ENSG00000142082 E010 1.3596026 0.015207267 7.192534e-01 0.8868074864 11 218778 218831 54 - 0.386 0.337 -0.289
ENSG00000142082 E011 9.5980806 0.040460769 4.135127e-01 0.6942379820 11 218832 219041 210 - 0.912 1.023 0.414
ENSG00000142082 E012 0.3812526 0.016137979 3.765964e-01   11 222379 223849 1471 - 0.000 0.177 11.005
ENSG00000142082 E013 0.0000000       11 224066 224077 12 -      
ENSG00000142082 E014 1.7517130 0.107944711 4.956648e-01 0.7567566691 11 224078 224089 12 - 0.317 0.454 0.778
ENSG00000142082 E015 3.8297987 0.004182211 3.765072e-01 0.6636773998 11 224090 224166 77 - 0.724 0.621 -0.434
ENSG00000142082 E016 2.5786031 0.005746918 1.178247e-01 0.3625674975 11 224167 224221 55 - 0.661 0.453 -0.959
ENSG00000142082 E017 1.4778011 0.009599161 4.468264e-01 0.7210776754 11 224222 224239 18 - 0.446 0.337 -0.611
ENSG00000142082 E018 0.0000000       11 225673 225761 89 -      
ENSG00000142082 E019 0.1186381 0.011839239 2.244015e-01   11 225762 226081 320 - 0.133 0.000 -11.719
ENSG00000142082 E020 2.9429483 0.005103783 5.587937e-02 0.2355843466 11 230452 230552 101 - 0.724 0.478 -1.097
ENSG00000142082 E021 0.1272623 0.012692958 1.000000e+00   11 230553 230602 50 - 0.000 0.067 9.420
ENSG00000142082 E022 0.0000000       11 230603 230641 39 -      
ENSG00000142082 E023 0.3813786 0.049967876 3.820719e-01   11 230642 230706 65 - 0.000 0.177 11.005
ENSG00000142082 E024 8.2942555 0.001761653 4.071413e-01 0.6896378313 11 232983 233191 209 - 0.982 0.914 -0.256
ENSG00000142082 E025 3.7097724 0.004652890 5.214869e-01 0.7753643054 11 233192 233208 17 - 0.694 0.621 -0.308
ENSG00000142082 E026 3.2109538 0.005072506 4.324047e-01 0.7098044680 11 233209 233215 7 - 0.661 0.566 -0.419
ENSG00000142082 E027 5.0967563 0.002942726 7.877046e-01 0.9186327682 11 233343 233437 95 - 0.724 0.767 0.176
ENSG00000142082 E028 3.2101880 0.006594760 4.295747e-01 0.7077984138 11 233438 233486 49 - 0.661 0.566 -0.419
ENSG00000142082 E029 2.2407130 0.008663875 7.560842e-01 0.9038582147 11 233487 233534 48 - 0.446 0.502 0.282
ENSG00000142082 E030 5.8216869 0.002950585 3.599476e-06 0.0001413941 11 233535 233910 376 - 0.235 0.922 3.363
ENSG00000142082 E031 2.2770041 0.006190872 7.058270e-03 0.0634256443 11 233911 234004 94 - 0.133 0.585 2.991
ENSG00000142082 E032 1.6248597 0.008469930 5.153516e-01 0.7714636239 11 236048 236193 146 - 0.317 0.427 0.640
ENSG00000142082 E033 2.1321464 0.006938775 2.044098e-01 0.4872767808 11 236194 236277 84 - 0.317 0.524 1.125
ENSG00000142082 E034 1.0046290 0.079385570 2.585286e-01 0.5508428102 11 236278 236354 77 - 0.133 0.337 1.710
ENSG00000142082 E035 0.3804973 0.015978333 3.770768e-01   11 236616 236931 316 - 0.000 0.177 11.005

Help

Please Click HERE to learn more details about the results from DEXseq.