ENSG00000142185

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000397928 ENSG00000142185 No_inf pgKDN_inf TRPM2 protein_coding protein_coding 114.8756 101.4864 85.14648 45.95874 0.9310093 -0.2532401 26.731987 6.540533 40.749757 3.7416411 2.7173754 2.6374612 0.29230833 0.123150 0.479625 0.356475 0.04461358 0.04461358 FALSE TRUE
ENST00000431901 ENSG00000142185 No_inf pgKDN_inf TRPM2 protein_coding protein_coding 114.8756 101.4864 85.14648 45.95874 0.9310093 -0.2532401 1.781762 5.345286 0.000000 3.0927335 0.0000000 -9.0648199 0.02950000 0.088500 0.000000 -0.088500 0.54291005 0.04461358 FALSE FALSE
ENST00000490982 ENSG00000142185 No_inf pgKDN_inf TRPM2 protein_coding protein_coding_CDS_not_defined 114.8756 101.4864 85.14648 45.95874 0.9310093 -0.2532401 10.785413 13.557801 7.740651 0.4647679 2.0868287 -0.8077976 0.12730833 0.202425 0.090850 -0.111575 0.50063059 0.04461358 FALSE TRUE
ENST00000498430 ENSG00000142185 No_inf pgKDN_inf TRPM2 protein_coding protein_coding_CDS_not_defined 114.8756 101.4864 85.14648 45.95874 0.9310093 -0.2532401 16.904059 8.581094 13.937409 2.3782331 1.2952630 0.6990834 0.16979167 0.118100 0.163725 0.045625 0.71750820 0.04461358 FALSE TRUE
ENST00000583496 ENSG00000142185 No_inf pgKDN_inf TRPM2 protein_coding snoRNA 114.8756 101.4864 85.14648 45.95874 0.9310093 -0.2532401 33.991716 47.227847 0.000000 47.2278474 0.0000000 -12.2057275 0.12314167 0.197675 0.000000 -0.197675 0.56119496 0.04461358   FALSE
MSTRG.18913.15 ENSG00000142185 No_inf pgKDN_inf TRPM2 protein_coding   114.8756 101.4864 85.14648 45.95874 0.9310093 -0.2532401 6.092262 9.216406 3.630702 2.1326726 0.8420475 -1.3415521 0.06975833 0.121900 0.042575 -0.079325 0.34598413 0.04461358 FALSE FALSE
MSTRG.18913.4 ENSG00000142185 No_inf pgKDN_inf TRPM2 protein_coding   114.8756 101.4864 85.14648 45.95874 0.9310093 -0.2532401 5.356665 2.104417 6.873135 0.4924402 0.6574848 1.7028062 0.05840833 0.036625 0.080500 0.043875 0.48952538 0.04461358 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000142185 E001 0.7160146 0.2802459783 5.990740e-01 8.242042e-01 21 44350163 44350275 113 + 0.259 0.136 -1.151
ENSG00000142185 E002 0.3522653 0.0236843607 3.760701e-01   21 44350304 44350354 51 + 0.173 0.000 -13.322
ENSG00000142185 E003 1.1945165 0.1846642250 5.279622e-01 7.798292e-01 21 44353050 44353192 143 + 0.362 0.239 -0.828
ENSG00000142185 E004 0.6003108 0.0152373156 6.039292e-01 8.272478e-01 21 44353525 44353549 25 + 0.218 0.136 -0.830
ENSG00000142185 E005 1.2083915 0.0108281255 9.401691e-01 9.830357e-01 21 44353550 44353600 51 + 0.331 0.323 -0.052
ENSG00000142185 E006 2.7646295 0.1646382801 8.472139e-01 9.457834e-01 21 44353601 44353620 20 + 0.577 0.506 -0.331
ENSG00000142185 E007 12.2794390 0.0016736533 4.264751e-01 7.050434e-01 21 44353621 44353687 67 + 1.116 1.052 -0.232
ENSG00000142185 E008 38.1505348 0.0004250675 7.294207e-02 2.743990e-01 21 44353688 44353835 148 + 1.591 1.503 -0.302
ENSG00000142185 E009 21.5108072 0.0014289909 5.850504e-02 2.422766e-01 21 44353836 44353865 30 + 1.362 1.234 -0.447
ENSG00000142185 E010 14.1909920 0.0050921605 2.750595e-01 5.685605e-01 21 44354648 44354651 4 + 1.182 1.093 -0.318
ENSG00000142185 E011 29.3573230 0.0212933156 2.555092e-01 5.474588e-01 21 44354652 44354736 85 + 1.480 1.396 -0.290
ENSG00000142185 E012 9.5167499 0.0015297036 5.299822e-01 7.812177e-01 21 44356223 44356748 526 + 1.013 0.958 -0.203
ENSG00000142185 E013 36.0224656 0.0009994259 1.711733e-01 4.434652e-01 21 44364114 44364282 169 + 1.561 1.493 -0.234
ENSG00000142185 E014 32.8637259 0.0004755467 1.496231e-01 4.119796e-01 21 44366754 44366934 181 + 1.525 1.450 -0.257
ENSG00000142185 E015 0.2530140 0.2736018375 1.013843e-01   21 44369121 44369176 56 + 0.000 0.239 12.277
ENSG00000142185 E016 10.2315365 0.0142017733 4.718434e-01 7.391346e-01 21 44369177 44369194 18 + 1.046 0.975 -0.260
ENSG00000142185 E017 30.0050704 0.0056209337 9.555102e-03 7.806716e-02 21 44369195 44369343 149 + 1.512 1.341 -0.589
ENSG00000142185 E018 44.8066178 0.0031640048 1.328822e-01 3.870425e-01 21 44375833 44376013 181 + 1.655 1.581 -0.254
ENSG00000142185 E019 29.7621576 0.0004720656 2.204387e-01 5.073921e-01 21 44377712 44377773 62 + 1.480 1.414 -0.226
ENSG00000142185 E020 53.2889598 0.0015055177 1.784631e-02 1.176428e-01 21 44378997 44379197 201 + 1.738 1.632 -0.359
ENSG00000142185 E021 31.1366135 0.0038337488 6.664147e-02 2.600203e-01 21 44382718 44382820 103 + 1.512 1.402 -0.377
ENSG00000142185 E022 37.0210999 0.0003950411 2.578585e-02 1.483924e-01 21 44390904 44391025 122 + 1.586 1.472 -0.390
ENSG00000142185 E023 22.4952359 0.0006482517 1.434867e-01 4.033993e-01 21 44391272 44391319 48 + 1.371 1.279 -0.323
ENSG00000142185 E024 36.7548883 0.0024287113 2.947507e-01 5.880110e-01 21 44391320 44391442 123 + 1.565 1.513 -0.178
ENSG00000142185 E025 22.3813108 0.0020831827 1.227992e-01 3.709148e-01 21 44391443 44391502 60 + 1.371 1.270 -0.353
ENSG00000142185 E026 30.7197494 0.0081942166 1.939709e-01 4.737705e-01 21 44391503 44391625 123 + 1.499 1.414 -0.290
ENSG00000142185 E027 35.0725100 0.0003854732 2.758842e-01 5.693405e-01 21 44395414 44395551 138 + 1.545 1.493 -0.179
ENSG00000142185 E028 34.5572760 0.0003971050 1.457557e-01 4.064622e-01 21 44397747 44397876 130 + 1.545 1.472 -0.252
ENSG00000142185 E029 42.1970197 0.0003227836 1.269026e-02 9.377127e-02 21 44399296 44399441 146 + 1.643 1.523 -0.409
ENSG00000142185 E030 44.2767307 0.0014172865 5.752307e-01 8.097747e-01 21 44400259 44400371 113 + 1.634 1.613 -0.073
ENSG00000142185 E031 67.3476942 0.0002192626 6.700704e-01 8.629935e-01 21 44401681 44401897 217 + 1.809 1.800 -0.032
ENSG00000142185 E032 39.1824623 0.0003699769 3.915695e-01 6.766677e-01 21 44405142 44405260 119 + 1.588 1.550 -0.127
ENSG00000142185 E033 45.2906735 0.0108647294 2.272606e-01 5.156314e-01 21 44405905 44406037 133 + 1.660 1.585 -0.256
ENSG00000142185 E034 63.1258226 0.0002693730 7.224548e-01 8.884375e-01 21 44406594 44406765 172 + 1.781 1.774 -0.025
ENSG00000142185 E035 75.4028005 0.0002030847 5.142090e-01 7.709244e-01 21 44413891 44414074 184 + 1.860 1.843 -0.058
ENSG00000142185 E036 24.7121695 0.0005677024 3.139513e-03 3.567774e-02 21 44417927 44417942 16 + 1.436 1.244 -0.669
ENSG00000142185 E037 63.6082710 0.0010293294 1.140817e-01 3.556578e-01 21 44417943 44418108 166 + 1.800 1.740 -0.204
ENSG00000142185 E038 53.3334292 0.0016565178 9.828418e-02 3.270569e-01 21 44418423 44418555 133 + 1.729 1.657 -0.242
ENSG00000142185 E039 3.8999295 0.0039771156 1.392551e-01 3.967348e-01 21 44418948 44419030 83 + 0.595 0.788 0.808
ENSG00000142185 E040 4.4916631 0.0034281412 9.477628e-08 5.550124e-06 21 44422270 44422419 150 + 0.392 1.038 2.755
ENSG00000142185 E041 5.8402487 0.0033566985 6.377342e-08 3.877740e-06 21 44423485 44423644 160 + 0.516 1.118 2.407
ENSG00000142185 E042 36.7745518 0.0032465257 4.017018e-01 6.847846e-01 21 44423645 44423732 88 + 1.531 1.585 0.185
ENSG00000142185 E043 38.3683341 0.0065299523 7.680352e-01 9.102346e-01 21 44424852 44424939 88 + 1.571 1.559 -0.039
ENSG00000142185 E044 0.9960996 0.1084356982 2.020338e-02 1.278480e-01 21 44425314 44425555 242 + 0.123 0.506 2.755
ENSG00000142185 E045 0.6242880 0.1946760466 5.008454e-02 2.210342e-01 21 44425556 44425669 114 + 0.066 0.392 3.170
ENSG00000142185 E046 65.9121406 0.0002474038 1.552150e-01 4.210313e-01 21 44425670 44425827 158 + 1.813 1.763 -0.168
ENSG00000142185 E047 36.7384309 0.0004417474 6.757732e-01 8.657692e-01 21 44426660 44426699 40 + 1.539 1.568 0.099
ENSG00000142185 E048 34.7333178 0.0004327884 2.738606e-01 5.676119e-01 21 44426700 44426736 37 + 1.503 1.568 0.223
ENSG00000142185 E049 46.6320178 0.0004409270 1.001106e-01 3.306175e-01 21 44427010 44427111 102 + 1.621 1.704 0.281
ENSG00000142185 E050 47.6761101 0.0033993820 3.164997e-01 6.094477e-01 21 44435131 44435217 87 + 1.639 1.698 0.198
ENSG00000142185 E051 28.5396353 0.0073902895 1.133216e-22 3.892922e-20 21 44435218 44436401 1184 + 1.111 1.768 2.275
ENSG00000142185 E052 41.2367220 0.0003458919 3.846109e-01 6.707497e-01 21 44437062 44437120 59 + 1.609 1.572 -0.125
ENSG00000142185 E053 38.0945552 0.0003736403 5.477712e-01 7.931778e-01 21 44437121 44437167 47 + 1.551 1.589 0.129
ENSG00000142185 E054 0.1271363 0.0122535039 2.253980e-01   21 44437168 44437175 8 + 0.000 0.136 12.533
ENSG00000142185 E055 0.0000000       21 44439035 44439066 32 +      
ENSG00000142185 E056 60.2409838 0.0002679800 3.842354e-01 6.703419e-01 21 44439067 44439168 102 + 1.744 1.787 0.144
ENSG00000142185 E057 93.4453125 0.0019220919 1.579326e-02 1.087998e-01 21 44440789 44440905 117 + 1.913 2.009 0.319
ENSG00000142185 E058 347.0068248 0.0012025591 8.361543e-08 4.950290e-06 21 44441692 44443085 1394 + 2.473 2.586 0.377

Help

Please Click HERE to learn more details about the results from DEXseq.