ENSG00000142186

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000270176 ENSG00000142186 No_inf pgKDN_inf SCYL1 protein_coding protein_coding 34.05514 33.20567 33.19473 1.407976 1.23811 -0.0004754669 17.5418408 14.519497 17.40874 3.3326981 3.4161103 0.2616552 0.51401667 0.439575 0.516125 0.076550 0.84875493 0.03896277 FALSE  
ENST00000420247 ENSG00000142186 No_inf pgKDN_inf SCYL1 protein_coding protein_coding 34.05514 33.20567 33.19473 1.407976 1.23811 -0.0004754669 8.0709221 4.845306 11.88583 2.7976784 2.0713926 1.2928218 0.23728333 0.142475 0.365425 0.222950 0.41509881 0.03896277 FALSE  
ENST00000524897 ENSG00000142186 No_inf pgKDN_inf SCYL1 protein_coding retained_intron 34.05514 33.20567 33.19473 1.407976 1.23811 -0.0004754669 0.9836420 2.950926 0.00000 1.2230152 0.0000000 -8.2099046 0.02900833 0.087025 0.000000 -0.087025 0.03896277 0.03896277 FALSE  
ENST00000532290 ENSG00000142186 No_inf pgKDN_inf SCYL1 protein_coding retained_intron 34.05514 33.20567 33.19473 1.407976 1.23811 -0.0004754669 2.3289270 3.689011 2.19307 0.5763291 0.8668265 -0.7476242 0.06830000 0.109775 0.064350 -0.045425 0.74110064 0.03896277 FALSE  
MSTRG.4951.2 ENSG00000142186 No_inf pgKDN_inf SCYL1 protein_coding   34.05514 33.20567 33.19473 1.407976 1.23811 -0.0004754669 0.9295553 2.788666 0.00000 2.7886658 0.0000000 -8.1285954 0.02945833 0.088375 0.000000 -0.088375 0.85814803 0.03896277 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000142186 E001 0.1272623 0.0123226989 0.5331072493   11 65525077 65525080 4 + 0.000 0.096 11.349
ENSG00000142186 E002 0.2537694 0.0160492261 0.2390426589   11 65525081 65525082 2 + 0.000 0.174 12.356
ENSG00000142186 E003 0.2537694 0.0160492261 0.2390426589   11 65525083 65525084 2 + 0.000 0.174 12.356
ENSG00000142186 E004 3.4229614 0.0432076846 0.9654125090 0.992727517 11 65525085 65525111 27 + 0.644 0.648 0.019
ENSG00000142186 E005 4.5124962 0.0241755262 0.6773207845 0.866229232 11 65525112 65525120 9 + 0.768 0.715 -0.215
ENSG00000142186 E006 16.3154107 0.0008620727 0.0945142755 0.319935538 11 65525121 65525264 144 + 1.295 1.177 -0.415
ENSG00000142186 E007 0.3627758 0.0166008178 0.5901543093   11 65525413 65525573 161 + 0.172 0.096 -0.981
ENSG00000142186 E008 21.3574668 0.0008082950 0.0010679208 0.015749860 11 65525574 65525714 141 + 1.443 1.237 -0.718
ENSG00000142186 E009 6.2138916 0.0529093532 0.4971246191 0.757887359 11 65525921 65525924 4 + 0.906 0.808 -0.379
ENSG00000142186 E010 20.1607773 0.0253430571 0.5966460128 0.822723089 11 65525925 65526043 119 + 1.350 1.300 -0.174
ENSG00000142186 E011 33.4354355 0.0076743444 0.1734848743 0.446771390 11 65526124 65526350 227 + 1.577 1.496 -0.277
ENSG00000142186 E012 20.0147999 0.0007592627 0.2344710179 0.523528196 11 65526783 65526873 91 + 1.360 1.284 -0.263
ENSG00000142186 E013 28.4349871 0.0035929901 0.6656752253 0.860951239 11 65526962 65527117 156 + 1.454 1.482 0.094
ENSG00000142186 E014 33.9091295 0.0004632610 0.9835935545 0.998690264 11 65530629 65530766 138 + 1.542 1.544 0.009
ENSG00000142186 E015 13.7453436 0.0010397240 0.0828830244 0.296676380 11 65530767 65530787 21 + 1.232 1.100 -0.471
ENSG00000142186 E016 30.7734334 0.0008892212 0.3541322039 0.643848518 11 65531576 65531683 108 + 1.526 1.478 -0.164
ENSG00000142186 E017 21.2236276 0.0043337843 0.2271311793 0.515446143 11 65532692 65532747 56 + 1.386 1.306 -0.280
ENSG00000142186 E018 20.6969676 0.0011072679 0.8886108174 0.962762873 11 65532748 65532805 58 + 1.331 1.341 0.036
ENSG00000142186 E019 0.6261154 0.0149323297 0.1699288923 0.442046249 11 65532806 65533258 453 + 0.095 0.298 2.019
ENSG00000142186 E020 0.3804973 0.0159314113 0.1010666322   11 65535131 65535226 96 + 0.000 0.240 12.941
ENSG00000142186 E021 31.0273089 0.0035905042 0.5466938885 0.792362361 11 65535227 65535333 107 + 1.487 1.522 0.122
ENSG00000142186 E022 19.7002412 0.0007382329 0.8614057383 0.951951830 11 65535334 65535382 49 + 1.321 1.311 -0.035
ENSG00000142186 E023 0.3812526 0.0158044924 0.1012336645   11 65535383 65535440 58 + 0.000 0.240 12.941
ENSG00000142186 E024 0.7521796 0.0146138130 0.0909285611 0.313068744 11 65535441 65535631 191 + 0.095 0.349 2.341
ENSG00000142186 E025 2.5206063 0.0058466463 0.0001363535 0.003061653 11 65535632 65535952 321 + 0.172 0.735 3.189
ENSG00000142186 E026 41.6392556 0.0003729569 0.7550870965 0.903589405 11 65535953 65536141 189 + 1.622 1.637 0.053
ENSG00000142186 E027 13.5558458 0.0010996037 0.0508144475 0.222996453 11 65536259 65536264 6 + 1.077 1.231 0.550
ENSG00000142186 E028 21.6564572 0.0205061736 0.1194858791 0.365388184 11 65536265 65536334 70 + 1.284 1.413 0.449
ENSG00000142186 E029 0.9874134 0.0119168459 0.4730188581 0.740157182 11 65536335 65536404 70 + 0.238 0.349 0.756
ENSG00000142186 E030 9.8361523 0.0023562312 0.2512456355 0.542526758 11 65536586 65536590 5 + 0.978 1.082 0.382
ENSG00000142186 E031 33.6977035 0.0004454694 0.0554390947 0.234617854 11 65536591 65536750 160 + 1.487 1.585 0.336
ENSG00000142186 E032 10.8286756 0.0018105592 0.1889930102 0.467575643 11 65536986 65537036 51 + 1.010 1.124 0.415
ENSG00000142186 E033 24.3040685 0.0007133387 0.4363619175 0.712805391 11 65537037 65537128 92 + 1.378 1.425 0.165
ENSG00000142186 E034 10.9063660 0.0012388404 0.8802584216 0.959592879 11 65537809 65537811 3 + 1.068 1.082 0.052
ENSG00000142186 E035 15.4510782 0.0009030661 0.6825179718 0.868584822 11 65537812 65537830 19 + 1.200 1.231 0.111
ENSG00000142186 E036 16.3867219 0.0008474635 0.6432194936 0.848695462 11 65537831 65537848 18 + 1.256 1.225 -0.110
ENSG00000142186 E037 20.7065902 0.0006461600 0.8895790174 0.963259416 11 65537849 65537880 32 + 1.331 1.341 0.036
ENSG00000142186 E038 1.1066248 0.1916556843 0.7503829486 0.901522631 11 65537881 65537966 86 + 0.295 0.349 0.340
ENSG00000142186 E039 20.2381699 0.0010482891 0.5453399193 0.791342854 11 65537967 65538003 37 + 1.306 1.346 0.142
ENSG00000142186 E040 35.7164733 0.0004303136 0.5298180976 0.781181438 11 65538004 65538182 179 + 1.579 1.550 -0.100
ENSG00000142186 E041 2.4838834 0.0073858203 0.0708905896 0.269672243 11 65538183 65538269 87 + 0.391 0.648 1.242
ENSG00000142186 E042 21.3022967 0.0106447379 0.7319545633 0.893412936 11 65538270 65538324 55 + 1.360 1.336 -0.081
ENSG00000142186 E043 3.7065292 0.0426595507 0.3401475106 0.631884953 11 65538325 65538441 117 + 0.593 0.735 0.604
ENSG00000142186 E044 11.8889294 0.0096098396 0.9589601386 0.990321987 11 65538442 65538446 5 + 1.111 1.108 -0.011
ENSG00000142186 E045 16.6496318 0.0284300796 0.7867149794 0.917975979 11 65538447 65538704 258 + 1.262 1.231 -0.109

Help

Please Click HERE to learn more details about the results from DEXseq.