ENSG00000143106

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000484563 ENSG00000143106 No_inf pgKDN_inf PSMA5 protein_coding protein_coding_CDS_not_defined 106.6665 58.72022 174.3931 4.698733 31.76165 1.57025 9.15205 6.792511 10.69240 1.457584 0.9381939 0.6537953 0.1011583 0.11695 0.067025 -0.049925 0.61902234 0.02566716 FALSE TRUE
ENST00000490870 ENSG00000143106 No_inf pgKDN_inf PSMA5 protein_coding protein_coding_CDS_not_defined 106.6665 58.72022 174.3931 4.698733 31.76165 1.57025 57.06749 42.055825 67.92513 2.080950 2.5614605 0.6915091 0.6361750 0.73560 0.424350 -0.311250 0.02566716 0.02566716 FALSE TRUE
ENST00000491287 ENSG00000143106 No_inf pgKDN_inf PSMA5 protein_coding protein_coding_CDS_not_defined 106.6665 58.72022 174.3931 4.698733 31.76165 1.57025 38.19217 6.932186 93.73005 6.932186 30.7317437 3.7552036 0.2334000 0.09550 0.495175 0.399675 0.03169602 0.02566716   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000143106 E001 14.3353631 0.0100125378 0.0001228732 0.002810451 1 109399042 109401849 2808 - 1.004 1.336 1.185
ENSG00000143106 E002 46.6871575 0.0004004123 0.7590146916 0.905378710 1 109401850 109402012 163 - 1.669 1.684 0.051
ENSG00000143106 E003 77.1340691 0.0002072087 0.2073166796 0.490963295 1 109402013 109402090 78 - 1.870 1.914 0.147
ENSG00000143106 E004 98.9004007 0.0001706796 0.8389911912 0.942201118 1 109409928 109410014 87 - 1.999 1.995 -0.015
ENSG00000143106 E005 114.5001155 0.0001751030 0.2414896026 0.531243636 1 109411011 109411113 103 - 2.073 2.043 -0.102
ENSG00000143106 E006 0.0000000       1 109411870 109411876 7 -      
ENSG00000143106 E007 104.3440522 0.0001638327 0.7154743764 0.885325876 1 109411877 109411935 59 - 2.024 2.015 -0.029
ENSG00000143106 E008 0.1186381 0.0118063466 0.7185998965   1 109411953 109412076 124 - 0.083 0.000 -8.941
ENSG00000143106 E009 146.7143053 0.0022616871 0.6231782630 0.837749163 1 109412077 109412184 108 - 2.172 2.160 -0.039
ENSG00000143106 E010 4.5263047 0.0032016178 0.4823242533 0.747240292 1 109412185 109413067 883 - 0.701 0.785 0.344
ENSG00000143106 E011 115.0645811 0.0004275158 0.6038668476 0.827211078 1 109413068 109413135 68 - 2.068 2.055 -0.043
ENSG00000143106 E012 0.8609688 0.0182511286 0.4549340757 0.727659816 1 109414809 109414904 96 - 0.213 0.329 0.837
ENSG00000143106 E013 139.2969982 0.0001494061 0.1749813602 0.448803723 1 109415237 109415363 127 - 2.158 2.127 -0.105
ENSG00000143106 E014 0.3729107 0.2968448256 0.4863023419   1 109415364 109415365 2 - 0.083 0.195 1.422
ENSG00000143106 E015 71.2866599 0.0002229982 0.9000642049 0.967540101 1 109421860 109421926 67 - 1.854 1.860 0.020
ENSG00000143106 E016 3.4581695 0.0106540964 0.0666415869 0.260020346 1 109425326 109426301 976 - 0.522 0.765 1.050
ENSG00000143106 E017 44.3542438 0.0271538478 0.5381780381 0.787044388 1 109426302 109426448 147 - 1.628 1.684 0.191

Help

Please Click HERE to learn more details about the results from DEXseq.