ENSG00000143119

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000271324 ENSG00000143119 No_inf pgKDN_inf CD53 protein_coding protein_coding 712.2456 562.8125 849.9122 7.533789 2.991606 0.5946508 504.85683 389.07931 607.17374 8.424614 22.123657 0.6420318 0.707300 0.691475 0.714675 0.023200 8.323176e-01 2.656625e-06 FALSE  
ENST00000464329 ENSG00000143119 No_inf pgKDN_inf CD53 protein_coding protein_coding_CDS_not_defined 712.2456 562.8125 849.9122 7.533789 2.991606 0.5946508 41.58894 66.28587 30.28903 3.050558 6.185029 -1.1296474 0.064075 0.117650 0.035625 -0.082025 2.656625e-06 2.656625e-06    
ENST00000648608 ENSG00000143119 No_inf pgKDN_inf CD53 protein_coding protein_coding 712.2456 562.8125 849.9122 7.533789 2.991606 0.5946508 142.90535 81.44781 186.62889 8.201422 18.517040 1.1961248 0.195350 0.144650 0.219375 0.074725 1.115391e-01 2.656625e-06 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000143119 E001 0.0000000       1 110871188 110871259 72 +      
ENSG00000143119 E002 2.0780451 7.272471e-03 6.647866e-01 8.606389e-01 1 110873148 110873155 8 + 0.456 0.521 0.319
ENSG00000143119 E003 85.6855344 1.696116e-04 2.248617e-02 1.363538e-01 1 110873156 110873182 27 + 1.964 1.891 -0.245
ENSG00000143119 E004 232.7973330 9.847130e-05 8.598334e-02 3.036753e-01 1 110873183 110873248 66 + 2.378 2.347 -0.105
ENSG00000143119 E005 0.3706447 1.935122e-01 4.453265e-01   1 110880237 110880332 96 + 0.082 0.199 1.489
ENSG00000143119 E006 363.3833031 6.093142e-05 1.764965e-02 1.167852e-01 1 110891392 110891471 80 + 2.572 2.538 -0.116
ENSG00000143119 E007 839.5068405 3.803196e-05 1.939423e-03 2.497037e-02 1 110892345 110892533 189 + 2.933 2.904 -0.094
ENSG00000143119 E008 9.3021733 2.114159e-03 6.939060e-06 2.490028e-04 1 110892534 110892855 322 + 0.775 1.198 1.577
ENSG00000143119 E009 3.4660427 4.025383e-03 1.806584e-02 1.186078e-01 1 110894309 110894326 18 + 0.487 0.794 1.337
ENSG00000143119 E010 483.5832718 4.710214e-04 4.088826e-01 6.910897e-01 1 110894327 110894401 75 + 2.686 2.676 -0.033
ENSG00000143119 E011 443.1912324 8.914909e-05 4.476582e-01 7.218368e-01 1 110894960 110895055 96 + 2.647 2.639 -0.026
ENSG00000143119 E012 415.9571662 2.226871e-04 2.484174e-01 5.392772e-01 1 110896653 110896733 81 + 2.607 2.628 0.071
ENSG00000143119 E013 20.1859505 7.073767e-04 1.783134e-16 3.497148e-14 1 110897670 110897808 139 + 0.986 1.554 2.004
ENSG00000143119 E014 441.8491187 5.654546e-05 4.869597e-01 7.506270e-01 1 110897809 110897892 84 + 2.637 2.650 0.044
ENSG00000143119 E015 2637.4157945 2.790415e-04 2.214139e-02 1.352252e-01 1 110899124 110899922 799 + 3.410 3.427 0.056

Help

Please Click HERE to learn more details about the results from DEXseq.