ENSG00000143314

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361531 ENSG00000143314 No_inf pgKDN_inf MRPL24 protein_coding protein_coding 62.38929 49.42346 70.50227 1.781123 2.717658 0.5123865 20.596322 10.627944 29.5840740 2.9498036 1.4377547 1.4760889 0.31772500 0.209550 0.419950 0.21040 0.1711213819 0.0001697241 FALSE TRUE
ENST00000368211 ENSG00000143314 No_inf pgKDN_inf MRPL24 protein_coding protein_coding 62.38929 49.42346 70.50227 1.781123 2.717658 0.5123865 25.009763 13.745071 28.7893687 2.9363242 1.6324478 1.0660736 0.39291667 0.285725 0.411025 0.12530 0.5229919534 0.0001697241 FALSE TRUE
ENST00000420938 ENSG00000143314 No_inf pgKDN_inf MRPL24 protein_coding protein_coding 62.38929 49.42346 70.50227 1.781123 2.717658 0.5123865 5.950270 5.703175 7.7324571 0.5764443 1.8390996 0.4384987 0.09558333 0.116500 0.107450 -0.00905 0.9431252208 0.0001697241   FALSE
ENST00000478899 ENSG00000143314 No_inf pgKDN_inf MRPL24 protein_coding protein_coding_CDS_not_defined 62.38929 49.42346 70.50227 1.781123 2.717658 0.5123865 6.973429 16.171015 0.9856369 2.6945078 0.9856369 -4.0225386 0.13093333 0.322725 0.013175 -0.30955 0.0001697241 0.0001697241 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000143314 E001 0.7257114 0.0985894633 0.78580546 0.91748733 1 156737303 156737304 2 - 0.253 0.206 -0.388
ENSG00000143314 E002 40.9997331 0.0003887800 0.04643251 0.21142178 1 156737305 156737529 225 - 1.578 1.666 0.302
ENSG00000143314 E003 15.8081279 0.0009684908 0.01215833 0.09127890 1 156737530 156737534 5 - 1.136 1.315 0.635
ENSG00000143314 E004 43.3898803 0.0006163047 0.13855148 0.39586212 1 156737646 156737776 131 - 1.613 1.678 0.221
ENSG00000143314 E005 32.7342763 0.0004529303 0.47454874 0.74124306 1 156738031 156738117 87 - 1.506 1.543 0.125
ENSG00000143314 E006 18.8552016 0.0007222841 0.78369252 0.91678357 1 156738118 156738134 17 - 1.284 1.302 0.066
ENSG00000143314 E007 1.1257545 0.0561021299 0.02797185 0.15622176 1 156738135 156738227 93 - 0.145 0.494 2.419
ENSG00000143314 E008 20.7299340 0.0007351838 0.28323466 0.57688740 1 156738343 156738417 75 - 1.358 1.289 -0.238
ENSG00000143314 E009 17.5451328 0.0009167663 0.10219441 0.33408616 1 156738418 156738438 21 - 1.305 1.191 -0.403
ENSG00000143314 E010 36.8804190 0.0004215924 0.01003489 0.08049105 1 156738522 156738633 112 - 1.619 1.495 -0.423
ENSG00000143314 E011 47.4660478 0.0003856794 0.03311942 0.17291627 1 156738634 156738764 131 - 1.713 1.625 -0.300
ENSG00000143314 E012 3.5620111 0.0189949506 0.10736675 0.34343859 1 156740379 156740562 184 - 0.553 0.767 0.912
ENSG00000143314 E013 1.7319148 0.0078353310 0.06518378 0.25705892 1 156740931 156741011 81 - 0.299 0.571 1.460
ENSG00000143314 E014 13.2226938 0.0031622737 0.53880352 0.78736937 1 156741012 156741052 41 - 1.166 1.117 -0.174
ENSG00000143314 E015 20.2430306 0.0013117411 0.32681618 0.61927434 1 156741053 156741131 79 - 1.346 1.282 -0.222
ENSG00000143314 E016 1.8490426 0.0106593767 0.11629185 0.35953480 1 156741180 156741590 411 - 0.340 0.571 1.197

Help

Please Click HERE to learn more details about the results from DEXseq.