ENSG00000143486

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000271764 ENSG00000143486 No_inf pgKDN_inf EIF2D protein_coding protein_coding 33.23843 41.88542 29.57308 3.591989 3.011733 -0.5020199 19.3740529 20.73155 15.9075570 3.3362456 1.8681630 -0.3819049 0.60557500 0.488050 0.566075 0.078025 0.843868855 0.002628796 FALSE TRUE
ENST00000367114 ENSG00000143486 No_inf pgKDN_inf EIF2D protein_coding protein_coding 33.23843 41.88542 29.57308 3.591989 3.011733 -0.5020199 1.4951745 0.00000 4.4855236 0.0000000 2.6055413 8.8123454 0.04600000 0.000000 0.138000 0.138000 0.387347716 0.002628796 FALSE TRUE
ENST00000468891 ENSG00000143486 No_inf pgKDN_inf EIF2D protein_coding retained_intron 33.23843 41.88542 29.57308 3.591989 3.011733 -0.5020199 2.3411791 4.67285 0.5355626 1.9175584 0.3146863 -3.1015701 0.06324167 0.107025 0.020350 -0.086675 0.581661353 0.002628796   FALSE
ENST00000484492 ENSG00000143486 No_inf pgKDN_inf EIF2D protein_coding nonsense_mediated_decay 33.23843 41.88542 29.57308 3.591989 3.011733 -0.5020199 3.8954772 5.52881 4.7009152 3.4765279 3.3017385 -0.2335688 0.09926667 0.116000 0.134825 0.018825 1.000000000 0.002628796 TRUE FALSE
ENST00000617960 ENSG00000143486 No_inf pgKDN_inf EIF2D protein_coding retained_intron 33.23843 41.88542 29.57308 3.591989 3.011733 -0.5020199 1.7938383 2.57134 1.2522928 0.1943986 0.1268878 -1.0320737 0.05425000 0.062425 0.044475 -0.017950 0.835370592 0.002628796   FALSE
MSTRG.2606.3 ENSG00000143486 No_inf pgKDN_inf EIF2D protein_coding   33.23843 41.88542 29.57308 3.591989 3.011733 -0.5020199 2.3912685 6.59441 0.0000000 3.6868566 0.0000000 -9.3672859 0.06838333 0.182975 0.000000 -0.182975 0.002628796 0.002628796 FALSE TRUE
MSTRG.2606.6 ENSG00000143486 No_inf pgKDN_inf EIF2D protein_coding   33.23843 41.88542 29.57308 3.591989 3.011733 -0.5020199 0.7192958 0.00000 1.7488189 0.0000000 1.7488189 7.4584631 0.02616667 0.000000 0.062850 0.062850 0.830338102 0.002628796 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000143486 E001 0.0000000       1 206571292 206571493 202 -      
ENSG00000143486 E002 0.1170040 0.0116997824 0.3293452878   1 206572595 206572699 105 - 0.117 0.000 -12.035
ENSG00000143486 E003 0.1268540 0.0123218407 0.8992409835   1 206580692 206580768 77 - 0.000 0.077 10.569
ENSG00000143486 E004 0.0000000       1 206580935 206581162 228 -      
ENSG00000143486 E005 1.9869749 0.0071410800 0.5536875302 0.79678175 1 206591642 206591700 59 - 0.407 0.495 0.456
ENSG00000143486 E006 21.7692791 0.0006488251 0.1234266467 0.37194868 1 206591701 206591845 145 - 1.401 1.304 -0.337
ENSG00000143486 E007 38.4549164 0.0004285278 0.3375896806 0.62940963 1 206593619 206593793 175 - 1.609 1.563 -0.158
ENSG00000143486 E008 20.8549988 0.0042652385 0.0786789596 0.28751121 1 206594040 206595709 1670 - 1.241 1.366 0.436
ENSG00000143486 E009 0.7536637 0.0293495235 0.2605058877 0.55307465 1 206595710 206595717 8 - 0.117 0.294 1.641
ENSG00000143486 E010 34.3411237 0.0006221425 0.9116126450 0.97179299 1 206595718 206595830 113 - 1.530 1.535 0.017
ENSG00000143486 E011 16.1484896 0.0010883532 0.5152978233 0.77146362 1 206595831 206595838 8 - 1.249 1.201 -0.169
ENSG00000143486 E012 35.2599690 0.0010952951 0.3910016105 0.67625323 1 206597100 206597195 96 - 1.571 1.527 -0.151
ENSG00000143486 E013 34.9235726 0.0092632690 0.7462680268 0.89966540 1 206599003 206599092 90 - 1.553 1.532 -0.071
ENSG00000143486 E014 37.5093656 0.0033211134 0.1624218628 0.43083060 1 206599463 206599612 150 - 1.522 1.596 0.255
ENSG00000143486 E015 2.1377822 0.1538861631 0.0597298885 0.24510932 1 206599613 206599732 120 - 0.209 0.591 2.225
ENSG00000143486 E016 31.1200895 0.0004575564 0.0522470427 0.22699307 1 206599733 206599836 104 - 1.422 1.527 0.362
ENSG00000143486 E017 18.9234938 0.0007554034 0.6348549595 0.84400538 1 206600263 206600308 46 - 1.264 1.296 0.111
ENSG00000143486 E018 24.4013248 0.0008186419 0.0007050655 0.01140240 1 206600309 206602335 2027 - 1.241 1.457 0.751
ENSG00000143486 E019 8.7726257 0.0015921560 0.9427069533 0.98412031 1 206602336 206602341 6 - 0.972 0.978 0.023
ENSG00000143486 E020 25.5918677 0.0120519275 0.7784099812 0.91486644 1 206602342 206602453 112 - 1.396 1.417 0.074
ENSG00000143486 E021 1.7195217 0.0148874987 0.7443337674 0.89877977 1 206602454 206602950 497 - 0.456 0.406 -0.266
ENSG00000143486 E022 27.1817345 0.0057429418 0.8385653131 0.94210680 1 206602951 206603082 132 - 1.427 1.439 0.042
ENSG00000143486 E023 19.7938791 0.0012559264 0.4596561358 0.73131075 1 206603083 206603204 122 - 1.271 1.320 0.172
ENSG00000143486 E024 1.4850381 0.0103393563 0.7181214385 0.88657055 1 206603205 206603501 297 - 0.350 0.406 0.319
ENSG00000143486 E025 0.5080420 0.0159800777 0.1230728097 0.37130441 1 206604609 206604729 121 - 0.000 0.249 12.569
ENSG00000143486 E026 0.0000000       1 206604730 206604732 3 -      
ENSG00000143486 E027 2.5973597 0.0063274869 0.9743024264 0.99538773 1 206604733 206605399 667 - 0.542 0.546 0.019
ENSG00000143486 E028 16.1208443 0.0008750777 0.2350046322 0.52416111 1 206605400 206605507 108 - 1.271 1.185 -0.305
ENSG00000143486 E029 8.9020811 0.0050158366 0.0062935672 0.05840283 1 206608236 206608279 44 - 1.127 0.868 -0.959
ENSG00000143486 E030 11.0465247 0.0314164170 0.2321763474 0.52082515 1 206608280 206608326 47 - 1.147 1.012 -0.488
ENSG00000143486 E031 13.8884237 0.0206707697 0.2516816197 0.54285929 1 206609376 206609459 84 - 1.225 1.113 -0.399
ENSG00000143486 E032 0.1170040 0.0116997824 0.3293452878   1 206611148 206611183 36 - 0.117 0.000 -12.037
ENSG00000143486 E033 23.1376636 0.0073108459 0.1976109323 0.47890918 1 206611184 206611374 191 - 1.422 1.332 -0.311
ENSG00000143486 E034 10.4418820 0.0014754936 0.1652222232 0.43479869 1 206612287 206612465 179 - 1.117 0.995 -0.443

Help

Please Click HERE to learn more details about the results from DEXseq.