ENSG00000143493

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000366992 ENSG00000143493 No_inf pgKDN_inf INTS7 protein_coding protein_coding 12.67661 11.4149 14.9919 1.421708 1.949511 0.3929636 1.7548133 0.0000000 3.3653375 0.0000000 1.1936830 8.3988880 0.12212500 0.000000 0.215125 0.215125 0.02836919 0.02836919 FALSE TRUE
ENST00000366993 ENSG00000143493 No_inf pgKDN_inf INTS7 protein_coding protein_coding 12.67661 11.4149 14.9919 1.421708 1.949511 0.3929636 0.6555558 0.3797720 0.8915205 0.3797720 0.8915205 1.2097299 0.05970000 0.026625 0.081900 0.055275 1.00000000 0.02836919 FALSE TRUE
ENST00000366994 ENSG00000143493 No_inf pgKDN_inf INTS7 protein_coding protein_coding 12.67661 11.4149 14.9919 1.421708 1.949511 0.3929636 3.9360186 4.5502093 4.2151527 0.4456131 0.7346294 -0.1100966 0.33580000 0.429475 0.299200 -0.130275 0.79450104 0.02836919 FALSE TRUE
ENST00000440600 ENSG00000143493 No_inf pgKDN_inf INTS7 protein_coding protein_coding 12.67661 11.4149 14.9919 1.421708 1.949511 0.3929636 1.6152690 0.6551798 1.7188974 0.3837810 1.0058950 1.3780361 0.13096667 0.058900 0.134275 0.075375 0.98346211 0.02836919 FALSE TRUE
ENST00000461212 ENSG00000143493 No_inf pgKDN_inf INTS7 protein_coding retained_intron 12.67661 11.4149 14.9919 1.421708 1.949511 0.3929636 1.1339232 0.7358512 1.5117114 0.7358512 0.7191314 1.0287351 0.07530000 0.054675 0.089900 0.035225 0.66152966 0.02836919 FALSE TRUE
ENST00000612340 ENSG00000143493 No_inf pgKDN_inf INTS7 protein_coding protein_coding 12.67661 11.4149 14.9919 1.421708 1.949511 0.3929636 2.5586232 5.0938904 2.5819792 1.3834134 1.5846190 -0.9775432 0.19169167 0.430375 0.144700 -0.285675 0.34263034 0.02836919 FALSE TRUE
MSTRG.2663.3 ENSG00000143493 No_inf pgKDN_inf INTS7 protein_coding   12.67661 11.4149 14.9919 1.421708 1.949511 0.3929636 0.7082680 0.0000000 0.4000246 0.0000000 0.4000246 5.3576384 0.05893333 0.000000 0.019750 0.019750 0.84565865 0.02836919 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000143493 E001 0.2543986 0.0160839672 0.121465180   1 211940399 211940402 4 - 0.000 0.208 9.981
ENSG00000143493 E002 0.6172395 0.0147235136 0.342698626 0.63409890 1 211940403 211940453 51 - 0.143 0.283 1.233
ENSG00000143493 E003 15.0846024 0.0010330959 0.001313152 0.01847731 1 211940454 211941347 894 - 1.091 1.320 0.812
ENSG00000143493 E004 1.5696271 0.0089662105 0.551403903 0.79527793 1 211941348 211941355 8 - 0.441 0.347 -0.522
ENSG00000143493 E005 5.2545339 0.0107516028 0.196577636 0.47738386 1 211941356 211941531 176 - 0.724 0.871 0.581
ENSG00000143493 E006 9.5438251 0.0033066702 0.045798700 0.20966871 1 211941532 211941722 191 - 0.936 1.112 0.648
ENSG00000143493 E007 32.2254073 0.0005516762 0.019536954 0.12511352 1 211941723 211942111 389 - 1.465 1.577 0.385
ENSG00000143493 E008 16.6297570 0.0008650832 0.983447217 0.99869026 1 211944784 211944954 171 - 1.241 1.236 -0.017
ENSG00000143493 E009 5.2156989 0.0047588775 0.832770024 0.93969220 1 211944955 211944969 15 - 0.798 0.771 -0.107
ENSG00000143493 E010 6.6688298 0.0025263633 0.712788574 0.88398305 1 211946607 211946645 39 - 0.895 0.853 -0.160
ENSG00000143493 E011 7.8888877 0.0018344407 0.756635896 0.90418099 1 211946646 211946705 60 - 0.955 0.922 -0.125
ENSG00000143493 E012 0.4801267 0.0157895034 0.587200247   1 211952427 211952568 142 - 0.200 0.116 -0.937
ENSG00000143493 E013 7.7386463 0.0022017937 0.322165376 0.61526389 1 211952569 211952610 42 - 0.974 0.871 -0.386
ENSG00000143493 E014 9.5706408 0.0015162357 0.538590691 0.78719683 1 211952611 211952701 91 - 1.040 0.981 -0.217
ENSG00000143493 E015 0.1187032 0.0119068546 0.878070783   1 211966124 211966429 306 - 0.078 0.000 -11.557
ENSG00000143493 E016 5.5550694 0.0028182430 0.388537943 0.67434499 1 211966430 211966498 69 - 0.849 0.748 -0.400
ENSG00000143493 E017 8.3862374 0.0066373962 0.767300850 0.90988171 1 211967878 211967981 104 - 0.955 0.981 0.098
ENSG00000143493 E018 7.7761532 0.0038976500 0.967413414 0.99341205 1 211968513 211968603 91 - 0.936 0.937 0.006
ENSG00000143493 E019 8.5300109 0.0018845207 0.346490674 0.63719224 1 211968604 211968707 104 - 0.936 1.021 0.317
ENSG00000143493 E020 11.6625909 0.0012562744 0.869889644 0.95521195 1 211975166 211975372 207 - 1.091 1.102 0.038
ENSG00000143493 E021 8.3855077 0.0031896366 0.955726699 0.98928280 1 211976582 211976719 138 - 0.964 0.967 0.010
ENSG00000143493 E022 11.2896809 0.0013965022 0.818205985 0.93383108 1 211978272 211978511 240 - 1.091 1.069 -0.081
ENSG00000143493 E023 3.8852624 0.0091490605 0.878023838 0.95852152 1 211981093 211981190 98 - 0.691 0.670 -0.089
ENSG00000143493 E024 4.7974487 0.0706981481 0.083144153 0.29713072 1 211982676 211982810 135 - 0.849 0.575 -1.136
ENSG00000143493 E025 5.5386109 0.0364744807 0.120643642 0.36741587 1 211987886 211988003 118 - 0.884 0.670 -0.855
ENSG00000143493 E026 2.6238837 0.0056690685 0.009669892 0.07862747 1 212006639 212006664 26 - 0.674 0.283 -2.015
ENSG00000143493 E027 4.8293439 0.0030109866 0.247758284 0.53848863 1 212006665 212006761 97 - 0.811 0.670 -0.575
ENSG00000143493 E028 8.9890213 0.0157559072 0.879842971 0.95948907 1 212007250 212007449 200 - 1.000 0.981 -0.069
ENSG00000143493 E029 3.3850851 0.3261557233 0.714696105 0.88505948 1 212011375 212011421 47 - 0.673 0.575 -0.429
ENSG00000143493 E030 0.0000000       1 212011422 212011627 206 -      
ENSG00000143493 E031 5.4656852 0.0507638154 0.895553778 0.96555248 1 212016886 212017023 138 - 0.798 0.814 0.064
ENSG00000143493 E032 5.7533197 0.0036302246 0.020436135 0.12865676 1 212020122 212020218 97 - 0.916 0.640 -1.102
ENSG00000143493 E033 5.6489369 0.0025465369 0.055956683 0.23574189 1 212020219 212020268 50 - 0.895 0.670 -0.897
ENSG00000143493 E034 0.0000000       1 212020721 212020754 34 -      
ENSG00000143493 E035 7.7592631 0.0018570941 0.638184218 0.84579992 1 212021083 212021212 130 - 0.955 0.906 -0.186
ENSG00000143493 E036 0.1176306 0.0118064511 0.878084061   1 212030737 212030940 204 - 0.078 0.000 -11.557
ENSG00000143493 E037 3.9236340 0.0039146265 0.102726685 0.33504077 1 212035344 212035403 60 - 0.595 0.793 0.828
ENSG00000143493 E038 4.0993475 0.0914263075 0.330740904 0.62315252 1 212035404 212035487 84 - 0.755 0.609 -0.614
ENSG00000143493 E039 2.0416639 0.0069305035 0.185386719 0.46312439 1 212035488 212035557 70 - 0.549 0.347 -1.053

Help

Please Click HERE to learn more details about the results from DEXseq.