ENSG00000143515

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000368489 ENSG00000143515 No_inf pgKDN_inf ATP8B2 protein_coding protein_coding 27.58727 34.24233 24.02015 2.319207 0.684145 -0.5113562 4.1813118 1.4711799 6.81424794 1.0027790 3.01591901 2.2039232 0.16774167 0.039375 0.295375 0.256000 4.526091e-01 7.154636e-05 FALSE TRUE
ENST00000505882 ENSG00000143515 No_inf pgKDN_inf ATP8B2 protein_coding retained_intron 27.58727 34.24233 24.02015 2.319207 0.684145 -0.5113562 4.4599703 5.3651956 3.99069421 1.8391946 1.49590964 -0.4260669 0.16230000 0.157975 0.161425 0.003450 1.000000e+00 7.154636e-05 FALSE TRUE
ENST00000514107 ENSG00000143515 No_inf pgKDN_inf ATP8B2 protein_coding retained_intron 27.58727 34.24233 24.02015 2.319207 0.684145 -0.5113562 1.8573209 5.5719626 0.00000000 1.8934292 0.00000000 -9.1246286 0.05202500 0.156075 0.000000 -0.156075 2.340893e-02 7.154636e-05   FALSE
ENST00000672630 ENSG00000143515 No_inf pgKDN_inf ATP8B2 protein_coding protein_coding 27.58727 34.24233 24.02015 2.319207 0.684145 -0.5113562 0.7704526 2.3113579 0.00000000 2.3113579 0.00000000 -7.8588252 0.02147500 0.064425 0.000000 -0.064425 8.968500e-01 7.154636e-05 FALSE TRUE
MSTRG.1933.1 ENSG00000143515 No_inf pgKDN_inf ATP8B2 protein_coding   27.58727 34.24233 24.02015 2.319207 0.684145 -0.5113562 1.9398899 0.4340718 4.00793253 0.2958585 1.82666704 3.1775884 0.07937500 0.013800 0.164800 0.151000 5.720283e-02 7.154636e-05 FALSE TRUE
MSTRG.1933.13 ENSG00000143515 No_inf pgKDN_inf ATP8B2 protein_coding   27.58727 34.24233 24.02015 2.319207 0.684145 -0.5113562 5.7780789 9.6875108 1.37065572 0.7289924 1.37065572 -2.8122609 0.19950000 0.285000 0.061975 -0.223025 3.162186e-02 7.154636e-05 FALSE TRUE
MSTRG.1933.6 ENSG00000143515 No_inf pgKDN_inf ATP8B2 protein_coding   27.58727 34.24233 24.02015 2.319207 0.684145 -0.5113562 4.6062808 1.9990119 5.91801404 1.2282768 3.58444037 1.5610628 0.18239167 0.064550 0.237775 0.173225 9.052712e-01 7.154636e-05 FALSE TRUE
MSTRG.1933.8 ENSG00000143515 No_inf pgKDN_inf ATP8B2 protein_coding   27.58727 34.24233 24.02015 2.319207 0.684145 -0.5113562 2.1488229 4.8997323 0.09881976 0.9029475 0.09881976 -5.4956319 0.06916667 0.144950 0.004050 -0.140900 7.154636e-05 7.154636e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000143515 E001 0.1186381 0.0118537798 5.574933e-01   1 154325481 154325524 44 + 0.093 0.000 -10.851
ENSG00000143515 E002 0.8290928 0.0960154428 8.719104e-03 7.331714e-02 1 154325525 154325552 28 + 0.428 0.000 -15.488
ENSG00000143515 E003 1.3092196 0.0101948162 4.646217e-03 4.697556e-02 1 154325553 154325604 52 + 0.532 0.097 -3.266
ENSG00000143515 E004 3.3462526 0.0459232489 6.499650e-04 1.070388e-02 1 154325605 154325702 98 + 0.830 0.301 -2.530
ENSG00000143515 E005 0.0000000       1 154327213 154327245 33 +      
ENSG00000143515 E006 0.1265070 0.0123076518 5.194550e-01   1 154327800 154327861 62 + 0.000 0.097 12.393
ENSG00000143515 E007 1.8080368 0.0279434403 9.074086e-02 3.128567e-01 1 154328105 154328123 19 + 0.561 0.301 -1.403
ENSG00000143515 E008 3.7178542 0.0043654862 2.670094e-03 3.161555e-02 1 154328124 154328172 49 + 0.830 0.439 -1.721
ENSG00000143515 E009 0.1272623 0.0123560867 5.194650e-01   1 154328799 154328799 1 + 0.000 0.097 12.393
ENSG00000143515 E010 0.5082326 0.0406006290 4.428507e-02 2.058267e-01 1 154328800 154329075 276 + 0.000 0.301 14.174
ENSG00000143515 E011 7.3810340 0.0019959812 2.185177e-02 1.342010e-01 1 154330396 154330454 59 + 1.025 0.795 -0.873
ENSG00000143515 E012 0.2537079 0.2651357834 2.898976e-01   1 154330455 154330702 248 + 0.000 0.176 12.752
ENSG00000143515 E013 10.0653924 0.0015806547 3.259523e-02 1.711239e-01 1 154330815 154330880 66 + 1.130 0.941 -0.690
ENSG00000143515 E014 9.0164429 0.0091722114 4.708225e-01 7.384147e-01 1 154330881 154330928 48 + 1.035 0.965 -0.257
ENSG00000143515 E015 11.7161015 0.0011934545 5.227002e-01 7.761499e-01 1 154331048 154331146 99 + 1.130 1.079 -0.185
ENSG00000143515 E016 8.8742897 0.0183353113 1.650368e-01 4.345601e-01 1 154331444 154331486 43 + 1.063 0.916 -0.545
ENSG00000143515 E017 7.6413251 0.0028894445 4.740518e-02 2.139609e-01 1 154331487 154331505 19 + 1.025 0.829 -0.742
ENSG00000143515 E018 0.6261805 0.0148262186 1.614775e-01 4.296135e-01 1 154331506 154331605 100 + 0.093 0.301 2.056
ENSG00000143515 E019 9.4779258 0.0040300114 6.695295e-02 2.608173e-01 1 154331606 154331678 73 + 1.098 0.929 -0.622
ENSG00000143515 E020 7.7787715 0.0020552444 1.101642e-01 3.482969e-01 1 154331954 154332024 71 + 1.015 0.860 -0.585
ENSG00000143515 E021 9.0513044 0.0015581173 7.568422e-01 9.042872e-01 1 154332618 154332697 80 + 1.015 0.988 -0.100
ENSG00000143515 E022 15.2569568 0.0010634299 3.370854e-01 6.290130e-01 1 154334107 154334265 159 + 1.245 1.175 -0.245
ENSG00000143515 E023 12.6138548 0.0011501446 1.780712e-02 1.174669e-01 1 154334503 154334591 89 + 1.220 1.031 -0.681
ENSG00000143515 E024 20.8638243 0.0128429929 4.691163e-01 7.371105e-01 1 154337348 154337544 197 + 1.368 1.311 -0.197
ENSG00000143515 E025 1.2353600 0.0102096013 4.946520e-01 7.559605e-01 1 154337545 154337846 302 + 0.292 0.397 0.641
ENSG00000143515 E026 0.2533610 0.0160110094 2.304973e-01   1 154340489 154340536 48 + 0.000 0.176 13.338
ENSG00000143515 E027 0.2533610 0.0160110094 2.304973e-01   1 154340537 154340543 7 + 0.000 0.176 13.338
ENSG00000143515 E028 25.6825246 0.0006146612 7.675105e-01 9.099889e-01 1 154340854 154341062 209 + 1.434 1.418 -0.054
ENSG00000143515 E029 1.4760721 0.0109109033 5.286071e-01 7.802047e-01 1 154341167 154341788 622 + 0.342 0.439 0.542
ENSG00000143515 E030 9.1582040 0.0035098189 6.795471e-01 8.676012e-01 1 154342480 154342523 44 + 1.025 0.988 -0.136
ENSG00000143515 E031 18.7432127 0.0010404128 8.896534e-01 9.632733e-01 1 154342796 154342961 166 + 1.290 1.300 0.037
ENSG00000143515 E032 16.1042680 0.0020761243 2.443564e-01 5.345413e-01 1 154343113 154343301 189 + 1.273 1.190 -0.295
ENSG00000143515 E033 11.9431086 0.0013063377 2.177796e-01 5.042908e-01 1 154343453 154343568 116 + 1.160 1.060 -0.359
ENSG00000143515 E034 18.6907383 0.0007205651 5.031048e-01 7.626537e-01 1 154343893 154344039 147 + 1.316 1.272 -0.152
ENSG00000143515 E035 7.7460675 0.0044100047 3.205668e-01 6.134708e-01 1 154344040 154344057 18 + 0.888 0.988 0.378
ENSG00000143515 E036 0.7265278 0.0272286373 4.446602e-01 7.192003e-01 1 154344122 154344128 7 + 0.292 0.176 -0.944
ENSG00000143515 E037 0.9710124 0.1576644784 5.860868e-01 8.163741e-01 1 154344129 154344142 14 + 0.342 0.243 -0.681
ENSG00000143515 E038 18.7757912 0.0080265021 3.295317e-01 6.219443e-01 1 154344143 154344254 112 + 1.256 1.332 0.264
ENSG00000143515 E039 0.6275005 0.0533043143 1.712033e-01 4.435218e-01 1 154344373 154344394 22 + 0.093 0.301 2.056
ENSG00000143515 E040 18.0220229 0.0121539692 5.010238e-01 7.610821e-01 1 154344395 154344500 106 + 1.250 1.306 0.194
ENSG00000143515 E041 22.5958136 0.0007391835 3.892443e-01 6.750594e-01 1 154344641 154344785 145 + 1.398 1.347 -0.178
ENSG00000143515 E042 3.8003129 0.0037603975 8.417631e-09 6.069472e-07 1 154344786 154344970 185 + 0.093 0.916 4.914
ENSG00000143515 E043 27.2326462 0.0004950827 3.471797e-01 6.377436e-01 1 154344971 154345154 184 + 1.422 1.476 0.186
ENSG00000143515 E044 0.3802150 0.0265188925 9.797217e-02   1 154345155 154345207 53 + 0.000 0.243 13.843
ENSG00000143515 E045 31.1139269 0.0008532274 6.862543e-01 8.703895e-01 1 154345322 154345545 224 + 1.495 1.518 0.079
ENSG00000143515 E046 17.2381305 0.0013261177 5.879019e-01 8.171602e-01 1 154345800 154345883 84 + 1.279 1.242 -0.128
ENSG00000143515 E047 36.7538090 0.0006686977 7.585913e-01 9.051739e-01 1 154346231 154346476 246 + 1.568 1.585 0.056
ENSG00000143515 E048 0.2362687 0.0157074335 2.547563e-01   1 154346615 154346619 5 + 0.170 0.000 -14.137
ENSG00000143515 E049 26.1328240 0.0077058741 4.554361e-01 7.279365e-01 1 154346620 154346758 139 + 1.406 1.458 0.178
ENSG00000143515 E050 21.1018073 0.0008308378 3.999364e-01 6.835954e-01 1 154348408 154348538 131 + 1.316 1.370 0.190
ENSG00000143515 E051 279.2935713 0.0001247552 1.444344e-04 3.203886e-03 1 154348840 154351307 2468 + 2.417 2.475 0.192

Help

Please Click HERE to learn more details about the results from DEXseq.