ENSG00000143575

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000328703 ENSG00000143575 No_inf pgKDN_inf HAX1 protein_coding protein_coding 86.37574 70.42073 89.43597 2.573367 1.366433 0.3448114 52.007116 31.911865 63.9418210 2.4648872 1.5210570 1.0024405 0.59215833 0.456450 0.71505 0.258600 0.0002380433 0.0002380433 FALSE TRUE
ENST00000457918 ENSG00000143575 No_inf pgKDN_inf HAX1 protein_coding protein_coding 86.37574 70.42073 89.43597 2.573367 1.366433 0.3448114 7.910119 6.379173 11.6724464 1.5446436 4.1260199 0.8706413 0.09296667 0.092650 0.12880 0.036150 0.9964913601 0.0002380433 FALSE TRUE
ENST00000492550 ENSG00000143575 No_inf pgKDN_inf HAX1 protein_coding retained_intron 86.37574 70.42073 89.43597 2.573367 1.366433 0.3448114 3.722033 7.811164 0.9046629 0.8360354 0.6018308 -3.0960713 0.04837500 0.110100 0.01040 -0.099700 0.0089436925 0.0002380433   FALSE
ENST00000532105 ENSG00000143575 No_inf pgKDN_inf HAX1 protein_coding protein_coding 86.37574 70.42073 89.43597 2.573367 1.366433 0.3448114 6.279624 7.746755 0.0000000 2.7740907 0.0000000 -9.5993094 0.07335833 0.108250 0.00000 -0.108250 0.0063606640 0.0002380433 FALSE TRUE
ENST00000696932 ENSG00000143575 No_inf pgKDN_inf HAX1 protein_coding protein_coding 86.37574 70.42073 89.43597 2.573367 1.366433 0.3448114 6.592676 4.998528 6.4041549 2.9680541 2.2020038 0.3568724 0.07540833 0.068625 0.07270 0.004075 0.8414126658 0.0002380433 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000143575 E001 0.4985363 0.0152694857 2.244756e-01   1 154272355 154272460 106 + 0.086 0.260 1.897
ENSG00000143575 E002 0.2363338 0.0156589329 3.277843e-01   1 154272554 154272588 35 + 0.158 0.000 -11.275
ENSG00000143575 E003 0.3549719 0.0157553924 1.531430e-01   1 154272589 154272606 18 + 0.220 0.000 -11.811
ENSG00000143575 E004 0.4814789 0.0152909270 4.368084e-01   1 154272607 154272608 2 + 0.220 0.105 -1.273
ENSG00000143575 E005 0.4814789 0.0152909270 4.368084e-01   1 154272609 154272615 7 + 0.220 0.105 -1.273
ENSG00000143575 E006 0.4814789 0.0152909270 4.368084e-01   1 154272616 154272618 3 + 0.220 0.105 -1.273
ENSG00000143575 E007 0.4814789 0.0152909270 4.368084e-01   1 154272619 154272619 1 + 0.220 0.105 -1.273
ENSG00000143575 E008 0.4814789 0.0152909270 4.368084e-01   1 154272620 154272620 1 + 0.220 0.105 -1.273
ENSG00000143575 E009 0.7266241 0.0314353054 5.840040e-01 0.8150095258 1 154272621 154272622 2 + 0.274 0.189 -0.688
ENSG00000143575 E010 0.7266241 0.0314353054 5.840040e-01 0.8150095258 1 154272623 154272623 1 + 0.274 0.189 -0.688
ENSG00000143575 E011 0.9725896 0.0128549330 6.919979e-01 0.8739291817 1 154272624 154272628 5 + 0.322 0.260 -0.425
ENSG00000143575 E012 1.6975171 0.0104878376 5.106973e-01 0.7680967349 1 154272629 154272632 4 + 0.474 0.374 -0.536
ENSG00000143575 E013 1.9508781 0.0092300339 9.516563e-01 0.9878454837 1 154272633 154272635 3 + 0.474 0.464 -0.050
ENSG00000143575 E014 1.9508781 0.0092300339 9.516563e-01 0.9878454837 1 154272636 154272636 1 + 0.474 0.464 -0.050
ENSG00000143575 E015 4.5706664 0.0030584102 2.183333e-02 0.1341347568 1 154272637 154272651 15 + 0.854 0.571 -1.173
ENSG00000143575 E016 5.2964117 0.0026855505 1.963855e-02 0.1255554163 1 154272652 154272652 1 + 0.905 0.631 -1.103
ENSG00000143575 E017 8.4472134 0.0016264451 1.350574e-02 0.0977349772 1 154272653 154272661 9 + 1.071 0.828 -0.910
ENSG00000143575 E018 9.1921606 0.0015114745 4.040696e-02 0.1949815859 1 154272662 154272667 6 + 1.086 0.893 -0.716
ENSG00000143575 E019 14.5381701 0.0009439285 5.436437e-02 0.2321847086 1 154272668 154272703 36 + 1.253 1.105 -0.528
ENSG00000143575 E020 27.7622900 0.0005636731 5.481194e-01 0.7933183428 1 154272704 154272776 73 + 1.474 1.439 -0.121
ENSG00000143575 E021 0.1268540 0.0122981743 4.302697e-01   1 154272777 154272782 6 + 0.000 0.105 9.977
ENSG00000143575 E022 0.8600624 0.0155048641 5.083289e-01 0.7665892385 1 154272783 154272895 113 + 0.220 0.320 0.727
ENSG00000143575 E023 1.8613221 0.0074368956 8.761747e-02 0.3067151830 1 154272896 154272985 90 + 0.322 0.571 1.312
ENSG00000143575 E024 2.7135020 0.0347351372 2.075370e-01 0.4911153106 1 154272986 154273233 248 + 0.474 0.658 0.843
ENSG00000143575 E025 1.9969196 0.0839818584 3.274047e-02 0.1716058850 1 154273234 154273335 102 + 0.274 0.631 1.897
ENSG00000143575 E026 14.7091500 0.0010999871 1.666305e-01 0.4369681532 1 154273336 154273358 23 + 1.145 1.246 0.360
ENSG00000143575 E027 45.0702199 0.0003347216 4.689952e-01 0.7370187457 1 154273359 154273479 121 + 1.648 1.678 0.101
ENSG00000143575 E028 41.5809264 0.0072228676 2.388341e-01 0.5278347686 1 154273480 154273534 55 + 1.659 1.590 -0.234
ENSG00000143575 E029 46.5059239 0.0085301735 4.847622e-02 0.2167454056 1 154273535 154273598 64 + 1.725 1.611 -0.387
ENSG00000143575 E030 3.4536355 0.0079972005 1.898726e-01 0.4687608076 1 154273599 154273749 151 + 0.561 0.729 0.727
ENSG00000143575 E031 2.5801075 0.0055732927 4.739020e-01 0.7407886620 1 154273750 154273773 24 + 0.505 0.602 0.450
ENSG00000143575 E032 26.9058532 0.0016623947 3.329261e-01 0.6249708029 1 154273774 154273782 9 + 1.471 1.412 -0.202
ENSG00000143575 E033 52.2983930 0.0014099993 6.470959e-01 0.8507122933 1 154273783 154273868 86 + 1.735 1.714 -0.073
ENSG00000143575 E034 43.4979451 0.0003530347 5.969607e-01 0.8229973636 1 154273869 154273924 56 + 1.659 1.634 -0.086
ENSG00000143575 E035 33.4052864 0.0189103448 9.054048e-01 0.9697150259 1 154273925 154273961 37 + 1.539 1.531 -0.026
ENSG00000143575 E036 6.4084239 0.0306284007 1.092692e-01 0.3470101836 1 154273962 154274908 947 + 0.766 0.963 0.759
ENSG00000143575 E037 1.2442363 0.0099672215 1.074266e-01 0.3435282895 1 154274909 154274949 41 + 0.220 0.464 1.535
ENSG00000143575 E038 46.3729597 0.0026900171 8.493829e-01 0.9464448423 1 154274950 154275001 52 + 1.671 1.678 0.023
ENSG00000143575 E039 2.4956806 0.0295370533 9.552211e-03 0.0780671602 1 154275002 154275077 76 + 0.322 0.707 1.897
ENSG00000143575 E040 2.5116060 0.0247220015 3.728312e-04 0.0069191717 1 154275078 154275153 76 + 0.220 0.751 2.815
ENSG00000143575 E041 67.4668584 0.0003121885 9.354329e-01 0.9814730346 1 154275154 154275260 107 + 1.834 1.835 0.003
ENSG00000143575 E042 3.8912508 0.0036857408 7.115564e-06 0.0002546588 1 154275261 154275392 132 + 0.322 0.908 2.691
ENSG00000143575 E043 74.9663703 0.0003460291 5.183662e-02 0.2259949855 1 154275393 154275483 91 + 1.849 1.912 0.214
ENSG00000143575 E044 0.6266187 0.0369857727 1.144975e-01 0.3564801936 1 154275484 154275615 132 + 0.086 0.320 2.312
ENSG00000143575 E045 92.7114215 0.0001730545 2.098802e-01 0.4942850226 1 154275616 154275875 260 + 1.954 1.989 0.118

Help

Please Click HERE to learn more details about the results from DEXseq.