ENSG00000143621

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361891 ENSG00000143621 No_inf pgKDN_inf ILF2 protein_coding protein_coding 116.1489 93.77028 135.2652 0.9088943 1.042792 0.5285406 106.703986 75.71979 129.978840 0.9835178 1.862054 0.779455 0.90935000 0.807825 0.961175 0.15335 0.0000417317 4.17317e-05 FALSE TRUE
ENST00000480213 ENSG00000143621 No_inf pgKDN_inf ILF2 protein_coding protein_coding_CDS_not_defined 116.1489 93.77028 135.2652 0.9088943 1.042792 0.5285406 9.074521 17.30488 5.286333 1.7360460 2.377460 -1.708947 0.08699167 0.184175 0.038825 -0.14535 0.0060729836 4.17317e-05   TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000143621 E001 19.0622559 0.0045557555 2.435054e-01 0.5335045985 1 153661788 153662064 277 - 1.259 1.345 0.302
ENSG00000143621 E002 347.4223803 0.0010182492 8.604388e-03 0.0726583799 1 153662065 153662556 492 - 2.516 2.566 0.166
ENSG00000143621 E003 104.2232091 0.0001963069 8.206419e-01 0.9350145039 1 153662705 153662795 91 - 2.014 2.024 0.032
ENSG00000143621 E004 115.4948694 0.0002332112 8.059083e-01 0.9281009814 1 153663019 153663133 115 - 2.064 2.060 -0.013
ENSG00000143621 E005 4.9983835 0.0033538750 5.729640e-06 0.0002113696 1 153663134 153663214 81 - 0.456 0.999 2.272
ENSG00000143621 E006 81.2079729 0.0001784175 8.606707e-01 0.9517246102 1 153663215 153663276 62 - 1.907 1.916 0.029
ENSG00000143621 E007 99.1720133 0.0004627563 9.080674e-01 0.9707194738 1 153664043 153664130 88 - 1.997 1.997 -0.002
ENSG00000143621 E008 104.0883914 0.0036742187 6.015848e-01 0.8257520828 1 153664396 153664474 79 - 2.025 2.008 -0.058
ENSG00000143621 E009 152.7074715 0.0002371191 3.199630e-01 0.6127502992 1 153665220 153665336 117 - 2.192 2.171 -0.071
ENSG00000143621 E010 104.7873921 0.0001789495 8.944292e-01 0.9650537874 1 153665663 153665728 66 - 2.021 2.020 -0.003
ENSG00000143621 E011 0.2530140 0.2497141576 1.933681e-01   1 153667283 153667554 272 - 0.000 0.198 10.175
ENSG00000143621 E012 107.3309162 0.0001728481 4.971986e-01 0.7579183844 1 153667555 153667657 103 - 2.021 2.044 0.075
ENSG00000143621 E013 73.9899277 0.0071921085 8.813378e-01 0.9601006577 1 153668000 153668077 78 - 1.873 1.869 -0.011
ENSG00000143621 E014 69.6233043 0.0002493566 3.730662e-04 0.0069191717 1 153668453 153668557 105 - 1.896 1.768 -0.430
ENSG00000143621 E015 0.1272623 0.0123301224 3.835100e-01   1 153668558 153668576 19 - 0.000 0.111 10.191
ENSG00000143621 E016 37.1087056 0.0004567357 8.315556e-02 0.2971506449 1 153669836 153669878 43 - 1.612 1.528 -0.285
ENSG00000143621 E017 39.3079561 0.0003630738 1.021765e-01 0.3340580179 1 153670171 153670230 60 - 1.633 1.557 -0.259
ENSG00000143621 E018 0.0000000       1 153670231 153670232 2 -      
ENSG00000143621 E019 19.6473772 0.0006701146 2.190811e-01 0.5057438649 1 153670918 153671028 111 - 1.344 1.265 -0.278

Help

Please Click HERE to learn more details about the results from DEXseq.