ENSG00000143633

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000366649 ENSG00000143633 No_inf pgKDN_inf C1orf131 protein_coding protein_coding 36.6989 38.2685 34.9696 2.946584 0.8260422 -0.1300206 15.321261 16.928292 11.466800 1.1330536 2.9288198 -0.5615680 0.42044167 0.452275 0.327525 -0.124750 0.68917579 0.03107841 FALSE TRUE
ENST00000366651 ENSG00000143633 No_inf pgKDN_inf C1orf131 protein_coding protein_coding 36.6989 38.2685 34.9696 2.946584 0.8260422 -0.1300206 14.225083 10.406138 20.162698 1.8588940 2.5536581 0.9535836 0.38946667 0.266500 0.579000 0.312500 0.03107841 0.03107841 FALSE TRUE
ENST00000462669 ENSG00000143633 No_inf pgKDN_inf C1orf131 protein_coding protein_coding_CDS_not_defined 36.6989 38.2685 34.9696 2.946584 0.8260422 -0.1300206 3.534543 6.464269 1.139391 1.4169661 0.5160216 -2.4938476 0.09260833 0.163525 0.031600 -0.131925 0.12124830 0.03107841   FALSE
ENST00000495795 ENSG00000143633 No_inf pgKDN_inf C1orf131 protein_coding protein_coding_CDS_not_defined 36.6989 38.2685 34.9696 2.946584 0.8260422 -0.1300206 2.642755 3.309489 1.515319 0.9208108 0.7626079 -1.1218500 0.07033333 0.085150 0.042125 -0.043025 0.68949100 0.03107841   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000143633 E001 0.2374063 0.2551724648 2.766090e-01   1 231223763 231223764 2 - 0.177 0.000 -10.169
ENSG00000143633 E002 68.7722887 0.0008332248 2.564527e-01 5.485434e-01 1 231223765 231224254 490 - 1.822 1.860 0.131
ENSG00000143633 E003 31.2137945 0.0014839808 3.505315e-01 6.407580e-01 1 231224255 231224314 60 - 1.532 1.484 -0.165
ENSG00000143633 E004 39.4325124 0.0007480082 2.492520e-02 1.451329e-01 1 231224315 231224414 100 - 1.657 1.555 -0.345
ENSG00000143633 E005 3.0771713 0.0058593242 4.001515e-01 6.836382e-01 1 231224415 231225470 1056 - 0.547 0.659 0.500
ENSG00000143633 E006 23.6242514 0.0025209064 6.338528e-01 8.434794e-01 1 231225471 231225502 32 - 1.406 1.377 -0.100
ENSG00000143633 E007 19.4368572 0.0084212407 4.942281e-01 7.558469e-01 1 231225503 231225523 21 - 1.336 1.285 -0.176
ENSG00000143633 E008 5.8986934 0.0032532043 1.442176e-06 6.370377e-05 1 231225524 231225922 399 - 0.442 1.021 2.429
ENSG00000143633 E009 0.8796326 0.0143384671 5.957820e-02 2.447476e-01 1 231226386 231226390 5 - 0.098 0.385 2.499
ENSG00000143633 E010 2.2400864 0.0063397139 7.593357e-02 2.815416e-01 1 231226391 231226492 102 - 0.354 0.612 1.293
ENSG00000143633 E011 3.4722041 0.1477134018 2.292585e-01 5.179707e-01 1 231226493 231226738 246 - 0.514 0.742 0.995
ENSG00000143633 E012 25.8805208 0.0027440654 1.725615e-01 4.453648e-01 1 231226739 231226825 87 - 1.470 1.390 -0.276
ENSG00000143633 E013 20.9101961 0.0006966382 1.857565e-01 4.636735e-01 1 231226973 231227068 96 - 1.294 1.377 0.290
ENSG00000143633 E014 16.2486812 0.0009352663 2.155295e-01 5.013025e-01 1 231229150 231229206 57 - 1.187 1.275 0.310
ENSG00000143633 E015 5.1969839 0.0027638790 9.653859e-02 3.235509e-01 1 231229207 231229209 3 - 0.680 0.870 0.763
ENSG00000143633 E016 0.4904501 0.0161229622 9.517499e-01   1 231236696 231238856 2161 - 0.177 0.169 -0.086
ENSG00000143633 E017 46.3759657 0.0003465397 2.640514e-01 5.571206e-01 1 231238857 231239188 332 - 1.698 1.653 -0.154
ENSG00000143633 E018 11.9729028 0.0153747658 3.465922e-01 6.372635e-01 1 231241024 231241187 164 - 1.157 1.068 -0.322

Help

Please Click HERE to learn more details about the results from DEXseq.