ENSG00000143740

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000426344 ENSG00000143740 No_inf pgKDN_inf SNAP47 protein_coding protein_coding 13.80551 9.412896 16.16578 0.6018606 1.738634 0.7795931 0.6290095 0.8006392 0.6398217 0.3753678 0.2362222 -0.3190161 0.05645833 0.093175 0.044325 -0.04885 0.84043696 0.04492858 FALSE TRUE
ENST00000480265 ENSG00000143740 No_inf pgKDN_inf SNAP47 protein_coding protein_coding_CDS_not_defined 13.80551 9.412896 16.16578 0.6018606 1.738634 0.7795931 0.2258597 0.6775790 0.0000000 0.3912400 0.0000000 -6.1034535 0.02313333 0.069400 0.000000 -0.06940 0.38157796 0.04492858 FALSE FALSE
ENST00000617596 ENSG00000143740 No_inf pgKDN_inf SNAP47 protein_coding protein_coding 13.80551 9.412896 16.16578 0.6018606 1.738634 0.7795931 3.7763900 3.0064817 4.6043778 1.7453838 2.7175932 0.6132693 0.33031667 0.336525 0.345675 0.00915 1.00000000 0.04492858 FALSE TRUE
ENST00000679561 ENSG00000143740 No_inf pgKDN_inf SNAP47 protein_coding protein_coding 13.80551 9.412896 16.16578 0.6018606 1.738634 0.7795931 1.7933517 0.4946950 4.8853600 0.4946950 2.0301320 3.2779311 0.11005000 0.050075 0.280075 0.23000 0.35031547 0.04492858 FALSE TRUE
ENST00000680202 ENSG00000143740 No_inf pgKDN_inf SNAP47 protein_coding protein_coding 13.80551 9.412896 16.16578 0.6018606 1.738634 0.7795931 1.0688272 3.2064815 0.0000000 1.8543238 0.0000000 -8.3293396 0.10980000 0.329400 0.000000 -0.32940 0.44472940 0.04492858 FALSE TRUE
MSTRG.2787.19 ENSG00000143740 No_inf pgKDN_inf SNAP47 protein_coding   13.80551 9.412896 16.16578 0.6018606 1.738634 0.7795931 2.9399607 0.0000000 5.6228012 0.0000000 2.7432525 9.1377087 0.15990833 0.000000 0.304150 0.30415 0.04492858 0.04492858 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000143740 E001 0.0000000       1 227728200 227728284 85 +      
ENSG00000143740 E002 0.0000000       1 227728539 227728548 10 +      
ENSG00000143740 E003 0.0000000       1 227728549 227728598 50 +      
ENSG00000143740 E004 0.0000000       1 227728599 227728617 19 +      
ENSG00000143740 E005 0.0000000       1 227728618 227728634 17 +      
ENSG00000143740 E006 0.1272623 0.012540234 0.44379264   1 227728635 227728640 6 + 0.000 0.105 10.762
ENSG00000143740 E007 0.1272623 0.012540234 0.44379264   1 227728641 227728656 16 + 0.000 0.105 12.384
ENSG00000143740 E008 0.1272623 0.012540234 0.44379264   1 227728657 227728685 29 + 0.000 0.105 12.384
ENSG00000143740 E009 0.1272623 0.012540234 0.44379264   1 227728686 227728687 2 + 0.000 0.105 12.384
ENSG00000143740 E010 0.1272623 0.012540234 0.44379264   1 227728688 227728689 2 + 0.000 0.105 12.384
ENSG00000143740 E011 0.1272623 0.012540234 0.44379264   1 227728690 227728706 17 + 0.000 0.105 12.384
ENSG00000143740 E012 0.1272623 0.012540234 0.44379264   1 227728707 227728786 80 + 0.000 0.105 12.384
ENSG00000143740 E013 0.0000000       1 227731585 227731712 128 +      
ENSG00000143740 E014 0.0000000       1 227731713 227731747 35 +      
ENSG00000143740 E015 0.0000000       1 227732389 227733518 1130 +      
ENSG00000143740 E016 0.0000000       1 227733519 227734352 834 +      
ENSG00000143740 E017 0.1186381 0.011975195 0.64920231   1 227734996 227735004 9 + 0.086 0.000 -12.548
ENSG00000143740 E018 0.1186381 0.011975195 0.64920231   1 227735005 227735427 423 + 0.086 0.000 -12.548
ENSG00000143740 E019 0.0000000       1 227735428 227735430 3 +      
ENSG00000143740 E020 0.0000000       1 227735431 227735434 4 +      
ENSG00000143740 E021 0.0000000       1 227735435 227735435 1 +      
ENSG00000143740 E022 1.2150348 0.036217143 0.74766186 0.90039957 1 227735436 227735499 64 + 0.365 0.321 -0.267
ENSG00000143740 E023 0.0000000       1 227735681 227735684 4 +      
ENSG00000143740 E024 0.0000000       1 227735685 227735730 46 +      
ENSG00000143740 E025 0.0000000       1 227736173 227736487 315 +      
ENSG00000143740 E026 0.0000000       1 227739206 227739222 17 +      
ENSG00000143740 E027 0.0000000       1 227739223 227739302 80 +      
ENSG00000143740 E028 14.2947754 0.001188613 0.69603137 0.87601232 1 227747692 227748062 371 + 1.164 1.205 0.145
ENSG00000143740 E029 11.3045395 0.001477784 0.27505965 0.56856053 1 227748063 227748233 171 + 1.123 1.046 -0.280
ENSG00000143740 E030 0.0000000       1 227749249 227749305 57 +      
ENSG00000143740 E031 0.0000000       1 227758606 227758659 54 +      
ENSG00000143740 E032 39.5165419 0.003651428 0.03069962 0.16481716 1 227758995 227759485 491 + 1.643 1.559 -0.286
ENSG00000143740 E033 0.0000000       1 227759486 227759652 167 +      
ENSG00000143740 E034 0.0000000       1 227763739 227763802 64 +      
ENSG00000143740 E035 0.1265070 0.012482699 0.44379936   1 227766072 227766130 59 + 0.000 0.105 12.384
ENSG00000143740 E036 12.3552932 0.001371861 0.02068728 0.12957017 1 227766959 227767083 125 + 1.196 1.024 -0.619
ENSG00000143740 E037 3.3488482 0.005969150 0.02657502 0.15111197 1 227767084 227768248 1165 + 0.473 0.772 1.318
ENSG00000143740 E038 0.2539903 0.016063348 0.18385950   1 227768249 227768364 116 + 0.000 0.189 13.276
ENSG00000143740 E039 2.0915186 0.013906300 0.27122270 0.56495835 1 227768365 227769438 1074 + 0.404 0.572 0.833
ENSG00000143740 E040 0.1170040 0.011829212 0.64922973   1 227769439 227769516 78 + 0.086 0.000 -12.548
ENSG00000143740 E041 0.3809057 0.016106678 0.07108744   1 227770417 227770532 116 + 0.000 0.260 13.780
ENSG00000143740 E042 0.5083889 0.015792968 0.02836615 0.15757544 1 227770571 227770744 174 + 0.000 0.321 14.128
ENSG00000143740 E043 5.6898916 0.007121044 0.00745143 0.06590446 1 227775789 227776970 1182 + 0.654 0.964 1.225
ENSG00000143740 E044 49.4834400 0.006896434 0.44946568 0.72315600 1 227780527 227781826 1300 + 1.680 1.726 0.154

Help

Please Click HERE to learn more details about the results from DEXseq.