ENSG00000143889

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000272249 ENSG00000143889 No_inf pgKDN_inf HNRNPLL protein_coding nonsense_mediated_decay 25.79108 30.16813 26.24049 2.081255 0.471529 -0.2011591 5.696326 5.318420 7.3079341 0.4715285 0.9279754 0.45772857 0.22346667 0.178450 0.280275 0.101825 0.56727596 0.01174393 FALSE TRUE
ENST00000409328 ENSG00000143889 No_inf pgKDN_inf HNRNPLL protein_coding protein_coding 25.79108 30.16813 26.24049 2.081255 0.471529 -0.2011591 9.900008 7.654536 12.0583058 0.6068623 1.3595236 0.65495285 0.40047500 0.260700 0.459875 0.199175 0.21499158 0.01174393 FALSE TRUE
ENST00000409636 ENSG00000143889 No_inf pgKDN_inf HNRNPLL protein_coding protein_coding 25.79108 30.16813 26.24049 2.081255 0.471529 -0.2011591 2.769099 4.951067 2.2745000 0.3557879 0.8244934 -1.11877211 0.10159167 0.165225 0.087450 -0.077775 0.64141540 0.01174393 FALSE TRUE
ENST00000410076 ENSG00000143889 No_inf pgKDN_inf HNRNPLL protein_coding protein_coding 25.79108 30.16813 26.24049 2.081255 0.471529 -0.2011591 2.364802 2.136849 2.0149320 0.5377895 0.3686074 -0.08434746 0.09474167 0.068675 0.076875 0.008200 0.96968689 0.01174393 FALSE TRUE
ENST00000441689 ENSG00000143889 No_inf pgKDN_inf HNRNPLL protein_coding protein_coding 25.79108 30.16813 26.24049 2.081255 0.471529 -0.2011591 2.416869 5.771173 1.4794327 1.9708368 1.4794327 -1.95659924 0.07823333 0.180500 0.054200 -0.126300 0.31962457 0.01174393 FALSE TRUE
MSTRG.16115.8 ENSG00000143889 No_inf pgKDN_inf HNRNPLL protein_coding   25.79108 30.16813 26.24049 2.081255 0.471529 -0.2011591 1.505526 3.512106 0.3884065 0.6523639 0.1299950 -3.14412534 0.05383333 0.116525 0.014650 -0.101875 0.01174393 0.01174393 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000143889 E001 0.0000000       2 38561969 38561977 9 -      
ENSG00000143889 E002 20.9279694 0.0011642424 1.330740e-03 0.0186663505 2 38561978 38563185 1208 - 1.212 1.422 0.734
ENSG00000143889 E003 10.3566159 0.0014892497 1.651802e-05 0.0005246661 2 38563186 38563507 322 - 0.791 1.192 1.491
ENSG00000143889 E004 19.3924646 0.0007988468 9.480228e-01 0.9864690322 2 38563508 38564031 524 - 1.305 1.310 0.019
ENSG00000143889 E005 23.3663182 0.0005972866 4.195109e-01 0.6991070177 2 38564032 38564237 206 - 1.357 1.407 0.171
ENSG00000143889 E006 3.2697079 0.0855363553 1.787438e-03 0.0234216890 2 38565827 38566200 374 - 0.250 0.800 2.773
ENSG00000143889 E007 0.4907023 0.0158538206 9.074967e-01   2 38568079 38568198 120 - 0.181 0.165 -0.164
ENSG00000143889 E008 22.5148602 0.0006626176 3.534036e-01 0.6431307890 2 38568199 38568297 99 - 1.337 1.395 0.200
ENSG00000143889 E009 23.5588912 0.0041076603 5.470322e-02 0.2329496607 2 38568386 38568443 58 - 1.316 1.441 0.433
ENSG00000143889 E010 40.1617758 0.0003790745 6.470104e-01 0.8506309310 2 38569133 38569334 202 - 1.601 1.622 0.074
ENSG00000143889 E011 23.6560418 0.0006537603 5.463477e-01 0.7921373711 2 38569804 38569925 122 - 1.409 1.374 -0.120
ENSG00000143889 E012 38.8120899 0.0003957678 2.128322e-01 0.4980212686 2 38573210 38573427 218 - 1.628 1.572 -0.192
ENSG00000143889 E013 18.8009983 0.0013150699 7.372352e-01 0.8958600279 2 38577461 38577532 72 - 1.282 1.305 0.081
ENSG00000143889 E014 0.7450359 0.0140513228 4.988818e-01 0.7592396102 2 38577533 38577600 68 - 0.181 0.284 0.836
ENSG00000143889 E015 2.1052999 0.0072625175 3.308216e-01 0.6231525203 2 38577920 38578002 83 - 0.407 0.549 0.710
ENSG00000143889 E016 7.2638121 0.0028004379 4.743104e-01 0.7410403939 2 38581075 38581814 740 - 0.874 0.947 0.279
ENSG00000143889 E017 1.2533638 0.0124640197 7.790778e-02 0.2855506867 2 38581815 38581912 98 - 0.181 0.455 1.836
ENSG00000143889 E018 14.5422093 0.0011313503 2.739443e-01 0.5676327189 2 38581913 38581980 68 - 1.232 1.152 -0.286
ENSG00000143889 E019 8.4592474 0.0018094264 9.043750e-01 0.9692628517 2 38581981 38581985 5 - 0.980 0.970 -0.039
ENSG00000143889 E020 0.1272623 0.0124239703 6.031720e-01   2 38581986 38582071 86 - 0.000 0.090 8.383
ENSG00000143889 E021 19.5820284 0.0007586075 4.571148e-01 0.7292119756 2 38582072 38582168 97 - 1.337 1.290 -0.164
ENSG00000143889 E022 0.0000000       2 38582169 38582173 5 -      
ENSG00000143889 E023 8.5633153 0.0094372935 6.484388e-01 0.8515736330 2 38583841 38583842 2 - 1.003 0.959 -0.164
ENSG00000143889 E024 7.1948400 0.0026479958 2.774441e-01 0.5707367947 2 38583843 38583845 3 - 0.968 0.860 -0.409
ENSG00000143889 E025 15.3778770 0.0035904676 1.862403e-01 0.4640914235 2 38583846 38583926 81 - 1.264 1.166 -0.348
ENSG00000143889 E026 36.6211640 0.0004442742 2.718180e-01 0.5655831518 2 38585644 38585881 238 - 1.601 1.550 -0.174
ENSG00000143889 E027 12.4910939 0.0022841602 4.347022e-01 0.7118575142 2 38591530 38591575 46 - 1.161 1.099 -0.221
ENSG00000143889 E028 11.9502079 0.0012404414 1.122167e-01 0.3521231909 2 38591576 38591648 73 - 1.176 1.048 -0.460
ENSG00000143889 E029 0.4991354 0.0152956719 3.787491e-01   2 38599898 38600026 129 - 0.100 0.229 1.421
ENSG00000143889 E030 18.0917621 0.0188021092 3.048778e-01 0.5981481098 2 38602438 38602600 163 - 1.327 1.235 -0.321
ENSG00000143889 E031 12.9909665 0.0012126076 2.474112e-03 0.0298721180 2 38602601 38602856 256 - 1.258 1.020 -0.851
ENSG00000143889 E032 6.4449204 0.0023994289 9.850850e-02 0.3274953739 2 38602857 38603036 180 - 0.956 0.784 -0.659
ENSG00000143889 E033 0.3714026 0.0167197958 6.577365e-01   2 38603168 38603586 419 - 0.100 0.165 0.836

Help

Please Click HERE to learn more details about the results from DEXseq.