ENSG00000144118

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000272519 ENSG00000144118 No_inf pgKDN_inf RALB protein_coding protein_coding 46.89067 51.32752 50.81008 1.351346 0.7999311 -0.01461491 30.372502 30.712402 33.58982 2.927100 1.2128699 0.1291627 0.6508667 0.595400 0.660700 0.065300 7.652725e-01 3.032211e-16 FALSE TRUE
ENST00000420510 ENSG00000144118 No_inf pgKDN_inf RALB protein_coding protein_coding 46.89067 51.32752 50.81008 1.351346 0.7999311 -0.01461491 7.945369 4.214676 13.50876 2.133676 0.8498579 1.6780508 0.1700333 0.083500 0.266325 0.182825 2.130519e-01 3.032211e-16 FALSE TRUE
MSTRG.16923.4 ENSG00000144118 No_inf pgKDN_inf RALB protein_coding   46.89067 51.32752 50.81008 1.351346 0.7999311 -0.01461491 5.017707 11.120103 0.00000 1.094699 0.0000000 -10.1202513 0.1050500 0.216125 0.000000 -0.216125 3.032211e-16 3.032211e-16   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000144118 E001 0.0000000       2 120240064 120240125 62 +      
ENSG00000144118 E002 0.2533610 1.593232e-02 2.520556e-01   2 120252805 120252820 16 + 0.000 0.171 10.873
ENSG00000144118 E003 0.3703650 1.650605e-02 6.011041e-01   2 120252821 120252849 29 + 0.096 0.171 0.964
ENSG00000144118 E004 0.4887212 9.162373e-02 9.733733e-01   2 120252850 120252851 2 + 0.175 0.171 -0.036
ENSG00000144118 E005 0.4887212 9.162373e-02 9.733733e-01   2 120252852 120252857 6 + 0.175 0.171 -0.036
ENSG00000144118 E006 1.9577432 1.085656e-02 9.541036e-01 0.9886952560 2 120252858 120252874 17 + 0.475 0.467 -0.036
ENSG00000144118 E007 15.5467072 8.543513e-04 8.330263e-03 0.0710443402 2 120252875 120252980 106 + 1.308 1.117 -0.678
ENSG00000144118 E008 0.8630785 1.277871e-02 7.355389e-01 0.8951504559 2 120253299 120253450 152 + 0.241 0.294 0.379
ENSG00000144118 E009 3.9262720 7.344975e-03 7.875163e-01 0.9185150878 2 120253451 120253731 281 + 0.674 0.708 0.145
ENSG00000144118 E010 0.3809703 2.232646e-02 1.096403e-01   2 120256600 120256653 54 + 0.000 0.237 12.947
ENSG00000144118 E011 4.1178216 3.636398e-03 7.396349e-02 0.2770558686 2 120278615 120278617 3 + 0.810 0.591 -0.910
ENSG00000144118 E012 21.5693980 6.829217e-04 5.499731e-02 0.2335978084 2 120278618 120278712 95 + 1.411 1.293 -0.413
ENSG00000144118 E013 21.0885656 6.673206e-04 7.798951e-01 0.9151859690 2 120278713 120278778 66 + 1.334 1.352 0.065
ENSG00000144118 E014 0.3706473 1.650923e-02 6.004552e-01   2 120280835 120280907 73 + 0.096 0.171 0.964
ENSG00000144118 E015 50.1525068 2.935300e-04 1.793361e-02 0.1180299184 2 120285874 120286048 175 + 1.756 1.660 -0.325
ENSG00000144118 E016 20.6938626 7.022457e-04 1.272841e-02 0.0939244616 2 120286049 120286066 18 + 1.411 1.253 -0.551
ENSG00000144118 E017 20.2597871 6.959808e-04 1.549455e-01 0.4205510467 2 120286067 120286082 16 + 1.372 1.282 -0.315
ENSG00000144118 E018 62.2776537 2.497837e-04 3.577151e-01 0.6472313105 2 120289580 120289757 178 + 1.817 1.785 -0.110
ENSG00000144118 E019 416.0093396 8.063805e-05 1.087703e-06 0.0000500975 2 120293141 120294710 1570 + 2.596 2.640 0.149

Help

Please Click HERE to learn more details about the results from DEXseq.