ENSG00000144136

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000272542 ENSG00000144136 No_inf pgKDN_inf SLC20A1 protein_coding protein_coding 186.9715 107.1293 209.3015 2.561618 2.011893 0.9661641 95.911022 34.652956 113.308643 3.6911968 2.358305 1.7089186 0.47977500 0.326175 0.541350 0.215175 0.002805111 0.002805111 FALSE TRUE
MSTRG.16846.1 ENSG00000144136 No_inf pgKDN_inf SLC20A1 protein_coding   186.9715 107.1293 209.3015 2.561618 2.011893 0.9661641 14.843955 7.997007 16.616821 0.7898173 2.741760 1.0541773 0.07850833 0.074350 0.079725 0.005375 1.000000000 0.002805111 FALSE TRUE
MSTRG.16846.11 ENSG00000144136 No_inf pgKDN_inf SLC20A1 protein_coding   186.9715 107.1293 209.3015 2.561618 2.011893 0.9661641 8.440664 9.176671 6.710853 0.1347249 0.368328 -0.4508978 0.05218333 0.085900 0.032050 -0.053850 0.011321146 0.002805111 FALSE TRUE
MSTRG.16846.5 ENSG00000144136 No_inf pgKDN_inf SLC20A1 protein_coding   186.9715 107.1293 209.3015 2.561618 2.011893 0.9661641 54.423439 43.428024 60.866361 4.7028096 1.948599 0.4869237 0.31171667 0.403250 0.290675 -0.112575 0.159067379 0.002805111 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000144136 E001 2.822135 2.654251e-02 1.190966e-01 3.647372e-01 2 112645912 112645938 27 + 0.474 0.698 1.010
ENSG00000144136 E002 65.914668 1.842491e-03 3.172630e-05 9.044007e-04 2 112645939 112646129 191 + 1.869 1.686 -0.617
ENSG00000144136 E003 204.581147 2.075170e-04 3.593368e-12 4.364971e-10 2 112646563 112647162 600 + 2.349 2.190 -0.532
ENSG00000144136 E004 76.423902 2.594690e-04 1.734573e-02 1.153260e-01 2 112647324 112647446 123 + 1.903 1.816 -0.293
ENSG00000144136 E005 40.509613 5.406660e-04 1.111334e-04 2.594748e-03 2 112647447 112647464 18 + 1.666 1.466 -0.683
ENSG00000144136 E006 1.570732 8.845271e-03 7.424270e-01 8.982269e-01 2 112647623 112647652 30 + 0.418 0.367 -0.285
ENSG00000144136 E007 57.847007 9.558255e-03 2.531328e-02 1.464228e-01 2 112647653 112647701 49 + 1.798 1.668 -0.439
ENSG00000144136 E008 36.383278 1.927082e-02 6.808672e-02 2.632205e-01 2 112647702 112647703 2 + 1.603 1.466 -0.467
ENSG00000144136 E009 41.678363 1.096744e-02 2.476545e-02 1.446502e-01 2 112647704 112647717 14 + 1.663 1.518 -0.496
ENSG00000144136 E010 43.227512 1.241540e-02 1.854683e-01 4.631535e-01 2 112647718 112647738 21 + 1.660 1.575 -0.288
ENSG00000144136 E011 5.343720 1.809734e-02 2.381439e-05 7.155460e-04 2 112651946 112652072 127 + 0.524 1.041 2.092
ENSG00000144136 E012 13.461567 1.249281e-03 1.038891e-07 6.044397e-06 2 112652270 112652701 432 + 0.942 1.361 1.503
ENSG00000144136 E013 72.249715 2.930003e-04 2.213110e-03 2.757900e-02 2 112652702 112652798 97 + 1.889 1.772 -0.392
ENSG00000144136 E014 2.220387 7.415863e-03 2.744356e-02 1.542938e-01 2 112652799 112652888 90 + 0.354 0.668 1.537
ENSG00000144136 E015 10.681785 1.280283e-03 6.470121e-01 8.506309e-01 2 112652889 112652947 59 + 1.038 1.078 0.148
ENSG00000144136 E016 16.292214 6.538724e-03 1.049162e-03 1.554937e-02 2 112652948 112653355 408 + 1.110 1.367 0.907
ENSG00000144136 E017 41.292616 3.417698e-04 7.347209e-19 1.791434e-16 2 112656246 112657121 876 + 1.410 1.825 1.416
ENSG00000144136 E018 103.907232 6.710535e-04 2.464802e-01 5.371394e-01 2 112657122 112657241 120 + 2.019 1.981 -0.125
ENSG00000144136 E019 39.832459 3.586198e-04 3.950258e-19 9.863575e-17 2 112657242 112658362 1121 + 1.388 1.814 1.455
ENSG00000144136 E020 21.710332 6.999267e-04 8.840721e-18 1.946185e-15 2 112658363 112658824 462 + 1.052 1.605 1.935
ENSG00000144136 E021 114.231798 3.211270e-04 3.216188e-01 6.146553e-01 2 112658825 112658950 126 + 2.057 2.027 -0.099
ENSG00000144136 E022 56.466736 6.692026e-03 3.240158e-01 6.165274e-01 2 112658951 112658973 23 + 1.763 1.709 -0.181
ENSG00000144136 E023 105.361423 1.565694e-04 1.975703e-01 4.788459e-01 2 112658974 112659094 121 + 2.025 1.986 -0.132
ENSG00000144136 E024 2.351608 5.017821e-02 2.579229e-02 1.483980e-01 2 112659095 112659203 109 + 0.354 0.698 1.662
ENSG00000144136 E025 401.502545 6.749873e-05 7.959551e-01 9.225901e-01 2 112659204 112659762 559 + 2.588 2.592 0.013
ENSG00000144136 E026 191.080223 7.015852e-04 9.489131e-01 9.867620e-01 2 112660387 112660572 186 + 2.269 2.267 -0.005
ENSG00000144136 E027 6.058136 2.472837e-03 7.899152e-05 1.950790e-03 2 112660573 112661141 569 + 0.628 1.054 1.669
ENSG00000144136 E028 138.024556 2.453199e-04 1.712289e-01 4.435667e-01 2 112661142 112661226 85 + 2.114 2.150 0.122
ENSG00000144136 E029 942.922021 4.332951e-04 1.728659e-02 1.150889e-01 2 112662864 112663825 962 + 2.950 2.975 0.082

Help

Please Click HERE to learn more details about the results from DEXseq.