ENSG00000144468

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000341329 ENSG00000144468 No_inf pgKDN_inf RHBDD1 protein_coding protein_coding 9.625678 9.628699 9.551558 0.6960693 1.005931 -0.01159265 6.0118462 5.3870670 5.9024323 0.2973238 0.5854937 0.1315762 0.63066667 0.564600 0.625675 0.061075 0.85010300 0.01153327 FALSE  
ENST00000424132 ENSG00000144468 No_inf pgKDN_inf RHBDD1 protein_coding protein_coding 9.625678 9.628699 9.551558 0.6960693 1.005931 -0.01159265 0.1719866 0.0000000 0.5159598 0.0000000 0.5159598 5.7168808 0.01863333 0.000000 0.055900 0.055900 0.84016946 0.01153327 FALSE  
ENST00000443477 ENSG00000144468 No_inf pgKDN_inf RHBDD1 protein_coding protein_coding 9.625678 9.628699 9.551558 0.6960693 1.005931 -0.01159265 0.2132746 0.6398238 0.0000000 0.6398238 0.0000000 -6.0219766 0.01943333 0.058300 0.000000 -0.058300 0.84692397 0.01153327 FALSE  
ENST00000450679 ENSG00000144468 No_inf pgKDN_inf RHBDD1 protein_coding protein_coding_CDS_not_defined 9.625678 9.628699 9.551558 0.6960693 1.005931 -0.01159265 0.7910548 1.0984591 0.7398032 0.2985180 0.4914420 -0.5639718 0.07775000 0.109825 0.066050 -0.043775 0.79442151 0.01153327    
ENST00000539613 ENSG00000144468 No_inf pgKDN_inf RHBDD1 protein_coding protein_coding_CDS_not_defined 9.625678 9.628699 9.551558 0.6960693 1.005931 -0.01159265 0.7201688 0.9574333 0.0000000 0.1360060 0.0000000 -6.5960904 0.07240000 0.098950 0.000000 -0.098950 0.01153327 0.01153327 FALSE  
MSTRG.17697.10 ENSG00000144468 No_inf pgKDN_inf RHBDD1 protein_coding   9.625678 9.628699 9.551558 0.6960693 1.005931 -0.01159265 0.6228192 0.3611176 1.3897962 0.2714355 0.4761433 1.9152685 0.07200833 0.042325 0.161100 0.118775 0.57740543 0.01153327 FALSE  
MSTRG.17697.13 ENSG00000144468 No_inf pgKDN_inf RHBDD1 protein_coding   9.625678 9.628699 9.551558 0.6960693 1.005931 -0.01159265 0.2807059 0.8421178 0.0000000 0.5455607 0.0000000 -6.4129810 0.02816667 0.084500 0.000000 -0.084500 0.51785694 0.01153327 TRUE  
MSTRG.17697.7 ENSG00000144468 No_inf pgKDN_inf RHBDD1 protein_coding   9.625678 9.628699 9.551558 0.6960693 1.005931 -0.01159265 0.2970940 0.0000000 0.6359217 0.0000000 0.4197408 6.0132875 0.02797500 0.000000 0.056800 0.056800 0.45449886 0.01153327 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000144468 E001 0.0000000       2 226835581 226835663 83 +      
ENSG00000144468 E002 0.0000000       2 226835936 226836033 98 +      
ENSG00000144468 E003 0.1187032 0.0117975383 0.569511764   2 226836034 226836043 10 + 0.092 0.000 -11.106
ENSG00000144468 E004 0.1187032 0.0117975383 0.569511764   2 226836044 226836049 6 + 0.092 0.000 -13.022
ENSG00000144468 E005 0.1187032 0.0117975383 0.569511764   2 226836050 226836053 4 + 0.092 0.000 -13.022
ENSG00000144468 E006 0.1187032 0.0117975383 0.569511764   2 226836054 226836055 2 + 0.092 0.000 -13.022
ENSG00000144468 E007 0.5988949 0.0149112275 0.193407212 0.47315499 2 226836056 226836081 26 + 0.290 0.098 -1.906
ENSG00000144468 E008 0.8427529 0.0150920236 0.286254645 0.57986812 2 226836082 226836087 6 + 0.339 0.178 -1.228
ENSG00000144468 E009 0.7616239 0.0187513797 0.007985297 0.06907442 2 226836088 226836199 112 + 0.000 0.401 14.581
ENSG00000144468 E010 1.6312477 0.0089327808 0.007127264 0.06382233 2 226837496 226837523 28 + 0.168 0.578 2.553
ENSG00000144468 E011 1.7488783 0.0087868804 0.022425496 0.13615858 2 226837524 226837547 24 + 0.233 0.578 1.968
ENSG00000144468 E012 3.3654017 0.0042120132 0.007140281 0.06387526 2 226837548 226837770 223 + 0.425 0.782 1.608
ENSG00000144468 E013 1.3698036 0.0096635269 0.105959865 0.34083852 2 226837771 226837838 68 + 0.233 0.480 1.509
ENSG00000144468 E014 0.8536718 0.0128334630 0.765558516 0.90886810 2 226838073 226838154 82 + 0.290 0.245 -0.321
ENSG00000144468 E015 1.3248585 0.0108932169 0.153329555 0.41789258 2 226839409 226839627 219 + 0.462 0.245 -1.321
ENSG00000144468 E016 2.7823103 0.0077315647 0.189012667 0.46760283 2 226864604 226864629 26 + 0.658 0.480 -0.813
ENSG00000144468 E017 16.5790253 0.0034505255 0.304114879 0.59754934 2 226864630 226865126 497 + 1.279 1.209 -0.247
ENSG00000144468 E018 7.0458988 0.0024399589 0.172887480 0.44586489 2 226867186 226867318 133 + 0.968 0.834 -0.512
ENSG00000144468 E019 0.0000000       2 226906712 226906746 35 +      
ENSG00000144468 E020 0.0000000       2 226906747 226906792 46 +      
ENSG00000144468 E021 3.4296881 0.0050653059 0.879750217 0.95944612 2 226906793 226906850 58 + 0.635 0.657 0.094
ENSG00000144468 E022 2.5671118 0.1153187990 0.835389090 0.94080047 2 226906851 226906881 31 + 0.557 0.548 -0.043
ENSG00000144468 E023 0.1187032 0.0117975383 0.569511764   2 226906882 226907021 140 + 0.092 0.000 -13.022
ENSG00000144468 E024 0.0000000       2 226908221 226908551 331 +      
ENSG00000144468 E025 2.9121420 0.0050215335 0.278444817 0.57168752 2 226908822 226908878 57 + 0.658 0.515 -0.643
ENSG00000144468 E026 7.9725029 0.0183806729 0.746414516 0.89970001 2 226914208 226914351 144 + 0.934 0.971 0.138
ENSG00000144468 E027 0.2435110 0.0162512805 0.963885133   2 226914352 226914637 286 + 0.092 0.098 0.094
ENSG00000144468 E028 0.1170040 0.0117296646 0.569429399   2 226935199 226935425 227 + 0.092 0.000 -13.023
ENSG00000144468 E029 0.8817731 0.2889925374 0.115509282 0.35828604 2 226988332 226988652 321 + 0.092 0.401 2.679
ENSG00000144468 E030 0.2543986 0.0161618960 0.223036106   2 226989667 226989682 16 + 0.000 0.178 13.215
ENSG00000144468 E031 132.3554136 0.0002381028 0.881969868 0.96033277 2 226995431 226999215 3785 + 2.125 2.125 0.003

Help

Please Click HERE to learn more details about the results from DEXseq.