ENSG00000144741

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000336733 ENSG00000144741 No_inf pgKDN_inf SLC25A26 protein_coding protein_coding 13.49824 13.58162 12.90218 1.802106 1.525711 -0.07398412 2.2326349 0.0000000 4.1036323 0.0000000 2.3773280 8.68426903 0.15315833 0.000000 0.264800 0.264800 0.44107945 0.00750502 FALSE TRUE
ENST00000686511 ENSG00000144741 No_inf pgKDN_inf SLC25A26 protein_coding protein_coding 13.49824 13.58162 12.90218 1.802106 1.525711 -0.07398412 2.5482620 2.8361144 2.8678691 1.0407719 0.6059826 0.01600734 0.19787500 0.227925 0.228750 0.000825 0.97261247 0.00750502 FALSE TRUE
ENST00000690560 ENSG00000144741 No_inf pgKDN_inf SLC25A26 protein_coding nonsense_mediated_decay 13.49824 13.58162 12.90218 1.802106 1.525711 -0.07398412 0.6310711 1.4577219 0.4354914 1.4577219 0.2913773 -1.72010926 0.04009167 0.091525 0.028750 -0.062775 0.86995541 0.00750502   FALSE
MSTRG.20329.15 ENSG00000144741 No_inf pgKDN_inf SLC25A26 protein_coding   13.49824 13.58162 12.90218 1.802106 1.525711 -0.07398412 2.8972795 5.9139683 0.0000000 2.1031809 0.0000000 -9.21042012 0.18970833 0.382950 0.000000 -0.382950 0.00750502 0.00750502 FALSE FALSE
MSTRG.20329.16 ENSG00000144741 No_inf pgKDN_inf SLC25A26 protein_coding   13.49824 13.58162 12.90218 1.802106 1.525711 -0.07398412 2.1383541 1.5325097 2.3632344 0.9177241 0.8400561 0.62157507 0.17947500 0.153600 0.203025 0.049425 0.83131747 0.00750502 TRUE TRUE
MSTRG.20329.5 ENSG00000144741 No_inf pgKDN_inf SLC25A26 protein_coding   13.49824 13.58162 12.90218 1.802106 1.525711 -0.07398412 1.8913566 0.3738905 2.0780460 0.3738905 0.8231365 2.44338679 0.14860000 0.026250 0.188000 0.161750 0.41113512 0.00750502 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000144741 E001 0.0000000       3 66133610 66133984 375 +      
ENSG00000144741 E002 0.0000000       3 66220732 66220741 10 +      
ENSG00000144741 E003 0.0000000       3 66220742 66220858 117 +      
ENSG00000144741 E004 0.0000000       3 66220859 66220903 45 +      
ENSG00000144741 E005 0.0000000       3 66220904 66220951 48 +      
ENSG00000144741 E006 0.0000000       3 66220952 66220988 37 +      
ENSG00000144741 E007 0.0000000       3 66220989 66220991 3 +      
ENSG00000144741 E008 0.0000000       3 66220992 66220996 5 +      
ENSG00000144741 E009 0.0000000       3 66220997 66221000 4 +      
ENSG00000144741 E010 0.0000000       3 66221001 66221006 6 +      
ENSG00000144741 E011 0.0000000       3 66221007 66221010 4 +      
ENSG00000144741 E012 0.0000000       3 66221011 66221011 1 +      
ENSG00000144741 E013 2.1063713 0.0285686627 2.131917e-01 0.49841158 3 66221012 66221063 52 + 0.386 0.576 0.951
ENSG00000144741 E014 4.8206072 0.0044728885 1.144020e-01 0.35634760 3 66221064 66221127 64 + 0.660 0.847 0.755
ENSG00000144741 E015 0.0000000       3 66230191 66230236 46 +      
ENSG00000144741 E016 0.0000000       3 66231786 66231872 87 +      
ENSG00000144741 E017 8.7972644 0.0018031136 7.680162e-01 0.91023462 3 66236544 66236700 157 + 1.002 0.980 -0.084
ENSG00000144741 E018 0.2441377 0.0162320545 9.725905e-01   3 66238565 66238695 131 + 0.093 0.097 0.077
ENSG00000144741 E019 12.1587227 0.0018648230 3.417792e-01 0.63328013 3 66243203 66243312 110 + 1.078 1.156 0.281
ENSG00000144741 E020 0.0000000       3 66261595 66261650 56 +      
ENSG00000144741 E021 13.3597208 0.0012513970 5.929396e-01 0.82055793 3 66262051 66262155 105 + 1.135 1.178 0.156
ENSG00000144741 E022 8.3946935 0.0016479063 1.564167e-01 0.42267616 3 66263332 66263379 48 + 1.032 0.905 -0.473
ENSG00000144741 E023 0.1170040 0.0119211695 5.600888e-01   3 66276365 66278402 2038 + 0.093 0.000 -12.780
ENSG00000144741 E024 0.1271363 0.0125137423 5.162950e-01   3 66299236 66299469 234 + 0.000 0.097 12.555
ENSG00000144741 E025 0.1265070 0.0123344360 5.165594e-01   3 66304453 66304537 85 + 0.000 0.097 12.555
ENSG00000144741 E026 0.1271363 0.0125137423 5.162950e-01   3 66304538 66305514 977 + 0.000 0.097 12.555
ENSG00000144741 E027 0.1268540 0.0124239808 5.164078e-01   3 66336621 66337384 764 + 0.000 0.097 12.555
ENSG00000144741 E028 0.0000000       3 66345287 66345346 60 +      
ENSG00000144741 E029 0.1272623 0.0124579314 5.163981e-01   3 66345996 66346363 368 + 0.000 0.097 12.555
ENSG00000144741 E030 5.2282452 0.0028425230 2.155096e-01 0.50130250 3 66346364 66346408 45 + 0.857 0.722 -0.536
ENSG00000144741 E031 0.8508016 0.0145353746 7.538501e-01 0.90317325 3 66346409 66354145 7737 + 0.291 0.244 -0.338
ENSG00000144741 E032 0.0000000       3 66356031 66356084 54 +      
ENSG00000144741 E033 7.5328763 0.0021875441 1.018111e-01 0.33327745 3 66362860 66362929 70 + 1.002 0.847 -0.586
ENSG00000144741 E034 0.2539903 0.0162418487 2.280748e-01   3 66368392 66368546 155 + 0.000 0.177 13.472
ENSG00000144741 E035 8.1738303 0.0019163420 3.940633e-05 0.00108602 3 66369478 66369542 65 + 1.119 0.722 -1.508
ENSG00000144741 E036 8.3440000 0.0472832152 6.680912e-02 0.26044278 3 66370529 66370602 74 + 1.069 0.847 -0.829
ENSG00000144741 E037 0.2536433 0.0161624759 2.282523e-01   3 66371202 66371413 212 + 0.000 0.177 13.472
ENSG00000144741 E038 18.7946946 0.0008389592 2.785710e-01 0.57177181 3 66377690 66377967 278 + 1.328 1.264 -0.224
ENSG00000144741 E039 4.0572089 0.0042818535 5.144794e-01 0.77108576 3 66377968 66378016 49 + 0.660 0.742 0.340
ENSG00000144741 E040 1.9931759 0.0085570417 3.475101e-02 0.17814474 3 66378017 66378070 54 + 0.291 0.604 1.662
ENSG00000144741 E041 1.6208647 0.0179849722 4.431432e-02 0.20585270 3 66378071 66378159 89 + 0.234 0.546 1.814
ENSG00000144741 E042 4.0795962 0.0034710341 8.813225e-02 0.30793339 3 66378160 66378409 250 + 0.587 0.798 0.884
ENSG00000144741 E043 2.6099413 0.0086672062 3.794464e-02 0.18795514 3 66378410 66378502 93 + 0.386 0.679 1.399
ENSG00000144741 E044 1.3593791 0.1116408474 3.764833e-01 0.66365706 3 66378503 66378506 4 + 0.291 0.441 0.884
ENSG00000144741 E045 5.7582509 0.0056638653 7.648391e-01 0.90850858 3 66378507 66379583 1077 + 0.812 0.847 0.138
ENSG00000144741 E046 0.0000000       3 66379584 66380008 425 +      
ENSG00000144741 E047 0.0000000       3 66380117 66380953 837 +      
ENSG00000144741 E048 3.3606750 0.0206958586 3.060661e-02 0.16459635 3 66381497 66383750 2254 + 0.463 0.762 1.325
ENSG00000144741 E049 2.7175767 0.0491627149 2.251680e-01 0.51282518 3 66386184 66388116 1933 + 0.463 0.655 0.884

Help

Please Click HERE to learn more details about the results from DEXseq.