ENSG00000144747

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000398559 ENSG00000144747 No_inf pgKDN_inf TMF1 protein_coding protein_coding 24.44884 12.71897 23.39921 3.640255 6.88209 0.8789609 6.888153 6.3341257 9.7971720 0.7372321 0.3110610 0.6284158 0.42815833 0.618325 0.501975 -0.116350 0.833261016 0.000625024 FALSE TRUE
ENST00000477872 ENSG00000144747 No_inf pgKDN_inf TMF1 protein_coding retained_intron 24.44884 12.71897 23.39921 3.640255 6.88209 0.8789609 11.419352 3.5973629 7.2762688 3.5973629 7.2762688 1.0142357 0.26195000 0.152275 0.165300 0.013025 0.993052687 0.000625024   FALSE
ENST00000488010 ENSG00000144747 No_inf pgKDN_inf TMF1 protein_coding nonsense_mediated_decay 24.44884 12.71897 23.39921 3.640255 6.88209 0.8789609 2.343267 0.0000000 4.1039291 0.0000000 0.9250589 8.6843731 0.11211667 0.000000 0.224325 0.224325 0.000625024 0.000625024 TRUE TRUE
ENST00000646708 ENSG00000144747 No_inf pgKDN_inf TMF1 protein_coding protein_coding 24.44884 12.71897 23.39921 3.640255 6.88209 0.8789609 1.259994 0.2722557 0.5930687 0.2722557 0.5930687 1.0953200 0.05043333 0.028775 0.013475 -0.015300 1.000000000 0.000625024 FALSE TRUE
MSTRG.20339.1 ENSG00000144747 No_inf pgKDN_inf TMF1 protein_coding   24.44884 12.71897 23.39921 3.640255 6.88209 0.8789609 2.026783 2.0813267 1.0988990 0.7542590 0.7198594 -0.9152904 0.11755833 0.166025 0.064950 -0.101075 0.683280654 0.000625024 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000144747 E001 0.1268540 0.0123206884 0.3781971534   3 69019827 69019841 15 - 0.000 0.111 8.963
ENSG00000144747 E002 92.8566437 0.0002046333 0.0006115834 0.0102058 3 69019842 69021847 2006 - 1.924 2.020 0.322
ENSG00000144747 E003 8.6572900 0.0259061692 0.4573886408 0.7292636 3 69021848 69021977 130 - 0.946 1.025 0.294
ENSG00000144747 E004 44.2067061 0.0055783054 0.7770858820 0.9143962 3 69021978 69023076 1099 - 1.644 1.661 0.056
ENSG00000144747 E005 9.3402936 0.0016023026 0.4957695753 0.7568309 3 69023077 69023144 68 - 1.037 0.975 -0.230
ENSG00000144747 E006 24.1325332 0.0048171212 0.5062482953 0.7650047 3 69023145 69023320 176 - 1.378 1.420 0.146
ENSG00000144747 E007 17.9158280 0.0149679922 0.2684773466 0.5620049 3 69024055 69024180 126 - 1.313 1.215 -0.344
ENSG00000144747 E008 0.2537694 0.0160477559 0.1454267087   3 69024282 69024395 114 - 0.000 0.199 12.239
ENSG00000144747 E009 1.5937705 0.1607965641 0.4566903992 0.7289692 3 69024799 69025559 761 - 0.349 0.482 0.720
ENSG00000144747 E010 20.4894483 0.0007685408 0.1478547654 0.4094054 3 69025560 69025712 153 - 1.366 1.273 -0.327
ENSG00000144747 E011 14.0864482 0.0071076682 0.5901987328 0.8186447 3 69025996 69026097 102 - 1.194 1.149 -0.161
ENSG00000144747 E012 0.3703650 0.0166053791 0.3923420241   3 69026098 69026100 3 - 0.081 0.199 1.497
ENSG00000144747 E013 14.6243477 0.0010661227 0.6807348569 0.8681671 3 69027900 69027992 93 - 1.176 1.207 0.110
ENSG00000144747 E014 0.3645386 0.2126571110 0.8547103716   3 69027993 69028098 106 - 0.150 0.111 -0.504
ENSG00000144747 E015 11.6999285 0.0091070024 0.8359323544 0.9411372 3 69028226 69028295 70 - 1.091 1.111 0.073
ENSG00000144747 E016 4.3644759 0.0042371365 0.5151163967 0.7713660 3 69029815 69029977 163 - 0.759 0.679 -0.326
ENSG00000144747 E017 0.0000000       3 69029978 69030007 30 -      
ENSG00000144747 E018 6.7038332 0.0052432046 0.7536535162 0.9031086 3 69033548 69033704 157 - 0.868 0.902 0.128
ENSG00000144747 E019 0.0000000       3 69035023 69035115 93 -      
ENSG00000144747 E020 13.6297880 0.0010360953 0.9166227929 0.9737743 3 69038564 69038720 157 - 1.158 1.166 0.029
ENSG00000144747 E021 18.5215261 0.0016774770 0.7500439346 0.9014575 3 69038843 69039009 167 - 1.277 1.299 0.076
ENSG00000144747 E022 15.5364619 0.0020223063 0.3620251459 0.6513047 3 69039551 69039693 143 - 1.243 1.175 -0.240
ENSG00000144747 E023 13.3448391 0.0021028552 0.3709798320 0.6590824 3 69042807 69042912 106 - 1.182 1.111 -0.254
ENSG00000144747 E024 8.7705036 0.0016212121 0.7879296912 0.9186636 3 69043750 69043791 42 - 0.975 1.001 0.094
ENSG00000144747 E025 9.0992934 0.0033366549 0.6273966237 0.8399455 3 69043792 69043876 85 - 1.020 0.975 -0.168
ENSG00000144747 E026 7.2293426 0.0271008384 0.0745417181 0.2783586 3 69044492 69044595 104 - 0.994 0.774 -0.842
ENSG00000144747 E027 0.4815466 0.0335650379 0.5160637310   3 69044596 69044628 33 - 0.209 0.111 -1.088
ENSG00000144747 E028 0.7345904 0.0134815029 0.6766123624 0.8659598 3 69047349 69047357 9 - 0.209 0.272 0.497
ENSG00000144747 E029 44.4998104 0.0004217389 0.0428055592 0.2016662 3 69047358 69048562 1205 - 1.690 1.602 -0.301
ENSG00000144747 E030 8.4999916 0.0065143093 0.6313356783 0.8418537 3 69051945 69052339 395 - 0.994 0.947 -0.174

Help

Please Click HERE to learn more details about the results from DEXseq.