ENSG00000145014

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000330115 ENSG00000145014 No_inf pgKDN_inf TMEM44 protein_coding protein_coding 14.0743 22.16657 10.86751 2.184925 0.8076165 -1.027689 1.1572531 2.0048611 0.7070369 0.5916093 0.2004222 -1.4905611 0.07736667 0.085775 0.062275 -0.023500 0.888922130 0.006465231 FALSE FALSE
ENST00000347147 ENSG00000145014 No_inf pgKDN_inf TMEM44 protein_coding protein_coding 14.0743 22.16657 10.86751 2.184925 0.8076165 -1.027689 2.7509774 0.7205434 4.7720499 0.7205434 0.5431800 2.7105873 0.26865000 0.038200 0.452700 0.414500 0.006465231 0.006465231 FALSE TRUE
ENST00000392432 ENSG00000145014 No_inf pgKDN_inf TMEM44 protein_coding protein_coding 14.0743 22.16657 10.86751 2.184925 0.8076165 -1.027689 0.9134104 2.7402311 0.0000000 1.1969766 0.0000000 -8.1034090 0.04507500 0.135225 0.000000 -0.135225 0.147999140 0.006465231 FALSE TRUE
ENST00000430601 ENSG00000145014 No_inf pgKDN_inf TMEM44 protein_coding nonsense_mediated_decay 14.0743 22.16657 10.86751 2.184925 0.8076165 -1.027689 0.6098782 1.8296345 0.0000000 1.4372665 0.0000000 -7.5232753 0.02260000 0.067800 0.000000 -0.067800 0.650807825 0.006465231 TRUE FALSE
ENST00000432352 ENSG00000145014 No_inf pgKDN_inf TMEM44 protein_coding protein_coding 14.0743 22.16657 10.86751 2.184925 0.8076165 -1.027689 0.7244286 1.0355921 1.1376937 0.3800982 0.9465197 0.1344175 0.04945833 0.044625 0.103750 0.059125 1.000000000 0.006465231 FALSE TRUE
ENST00000476750 ENSG00000145014 No_inf pgKDN_inf TMEM44 protein_coding protein_coding_CDS_not_defined 14.0743 22.16657 10.86751 2.184925 0.8076165 -1.027689 3.2812751 5.6380407 2.1742463 0.8560858 0.8579082 -1.3706149 0.21968333 0.260650 0.192275 -0.068375 0.834050987 0.006465231   FALSE
ENST00000477651 ENSG00000145014 No_inf pgKDN_inf TMEM44 protein_coding retained_intron 14.0743 22.16657 10.86751 2.184925 0.8076165 -1.027689 2.4318775 5.0891121 0.8340186 0.7991857 0.2629941 -2.5948994 0.15049167 0.227200 0.073175 -0.154025 0.159363489 0.006465231 FALSE TRUE
MSTRG.21316.4 ENSG00000145014 No_inf pgKDN_inf TMEM44 protein_coding   14.0743 22.16657 10.86751 2.184925 0.8076165 -1.027689 1.3446489 2.1652011 0.7938292 0.6260319 0.4174345 -1.4361879 0.09680000 0.096375 0.069200 -0.027175 0.853549116 0.006465231 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000145014 E001 0.1265070 0.012584939 1.000000000   3 194587673 194587677 5 - 0.000 0.071 8.808
ENSG00000145014 E002 0.2451451 0.016605394 0.612405792   3 194587678 194587680 3 - 0.126 0.071 -0.926
ENSG00000145014 E003 9.0761793 0.001647272 0.443949267 0.71860624 3 194587681 194587872 192 - 0.925 1.002 0.287
ENSG00000145014 E004 43.9330311 0.001793871 0.524010469 0.77715395 3 194587873 194588447 575 - 1.642 1.618 -0.082
ENSG00000145014 E005 6.5761351 0.011678203 0.740873980 0.89714860 3 194588448 194588468 21 - 0.828 0.869 0.156
ENSG00000145014 E006 9.0458225 0.002025891 0.994425954 1.00000000 3 194588469 194588528 60 - 0.975 0.979 0.015
ENSG00000145014 E007 8.8284612 0.001681439 0.393207958 0.67817716 3 194588529 194588639 111 - 0.908 0.995 0.326
ENSG00000145014 E008 1.3884648 0.009881080 0.053112133 0.22926027 3 194589768 194589946 179 - 0.126 0.443 2.396
ENSG00000145014 E009 0.4982566 0.015398578 0.728538963   3 194593041 194593070 30 - 0.126 0.185 0.659
ENSG00000145014 E010 0.6251106 0.014969586 0.504599625 0.76367473 3 194593071 194593073 3 - 0.126 0.233 1.074
ENSG00000145014 E011 0.2536433 0.016246261 0.563607175   3 194596869 194597329 461 - 0.000 0.132 11.954
ENSG00000145014 E012 3.3766385 0.005362755 0.174800922 0.44860449 3 194604287 194604313 27 - 0.481 0.675 0.881
ENSG00000145014 E013 8.3732429 0.001995883 0.148432240 0.41032892 3 194604314 194604441 128 - 1.033 0.899 -0.499
ENSG00000145014 E014 3.1688598 0.054101730 0.038925482 0.19099408 3 194604442 194604445 4 - 0.783 0.470 -1.374
ENSG00000145014 E015 3.7859733 0.033060559 0.036866061 0.18486806 3 194610916 194610925 10 - 0.828 0.542 -1.207
ENSG00000145014 E016 9.1277103 0.001959035 0.259602635 0.55206248 3 194610926 194611020 95 - 1.046 0.945 -0.373
ENSG00000145014 E017 9.9535825 0.009335600 0.319239110 0.61197235 3 194615569 194615670 102 - 0.942 1.046 0.383
ENSG00000145014 E018 4.9806578 0.024449308 0.412725558 0.69378421 3 194615671 194615697 27 - 0.673 0.789 0.473
ENSG00000145014 E019 0.5002381 0.024620307 0.729494466 0.89215825 3 194616481 194616587 107 - 0.126 0.185 0.659
ENSG00000145014 E020 1.0060809 0.066214701 0.191184696 0.47061238 3 194616770 194616891 122 - 0.126 0.351 1.882
ENSG00000145014 E021 11.1966141 0.003942088 0.277532901 0.57076993 3 194617099 194617269 171 - 0.990 1.092 0.374
ENSG00000145014 E022 7.0313093 0.002113567 0.002100330 0.02654152 3 194617270 194617635 366 - 0.606 0.971 1.459
ENSG00000145014 E023 3.9187057 0.084702929 0.002487866 0.02999789 3 194617636 194617776 141 - 0.224 0.789 2.932
ENSG00000145014 E024 5.8839908 0.044849004 0.107626997 0.34396506 3 194622548 194623223 676 - 0.641 0.879 0.962
ENSG00000145014 E025 5.2781671 0.002722622 0.097508341 0.32537519 3 194623224 194623310 87 - 0.889 0.706 -0.724
ENSG00000145014 E026 8.9793798 0.001614225 0.086914796 0.30554117 3 194623529 194623695 167 - 1.072 0.918 -0.568
ENSG00000145014 E027 3.0451943 0.005240483 0.027624889 0.15503858 3 194625897 194625926 30 - 0.758 0.470 -1.274
ENSG00000145014 E028 4.7799761 0.006707698 0.068378466 0.26391328 3 194625927 194625990 64 - 0.870 0.658 -0.852
ENSG00000145014 E029 5.3349803 0.045604528 0.891033127 0.96368612 3 194628383 194628509 127 - 0.758 0.789 0.125
ENSG00000145014 E030 1.9849052 0.007645821 0.799549405 0.92478527 3 194628510 194628672 163 - 0.429 0.470 0.212
ENSG00000145014 E031 4.4353455 0.023892709 0.397705697 0.68187973 3 194633079 194633440 362 - 0.783 0.675 -0.440
ENSG00000145014 E032 0.4810357 0.026491580 0.102747043   3 194633563 194633689 127 - 0.304 0.071 -2.511

Help

Please Click HERE to learn more details about the results from DEXseq.