ENSG00000145495

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000274140 ENSG00000145495 No_inf pgKDN_inf MARCHF6 protein_coding protein_coding 67.95121 64.12994 61.61937 2.794993 1.254362 -0.05760508 11.072408 11.742076 11.895782 0.4176461 0.5982803 0.01874670 0.17075000 0.184425 0.193750 0.009325 9.724871e-01 9.504808e-07 FALSE  
ENST00000449913 ENSG00000145495 No_inf pgKDN_inf MARCHF6 protein_coding protein_coding 67.95121 64.12994 61.61937 2.794993 1.254362 -0.05760508 5.709036 1.963343 4.682927 1.1546313 2.7168239 1.24984591 0.09013333 0.029450 0.074675 0.045225 9.652392e-01 9.504808e-07 FALSE  
ENST00000503788 ENSG00000145495 No_inf pgKDN_inf MARCHF6 protein_coding protein_coding 67.95121 64.12994 61.61937 2.794993 1.254362 -0.05760508 3.377520 0.000000 7.592636 0.0000000 4.4611930 9.57035588 0.04848333 0.000000 0.124875 0.124875 4.686435e-01 9.504808e-07 FALSE  
ENST00000510792 ENSG00000145495 No_inf pgKDN_inf MARCHF6 protein_coding protein_coding 67.95121 64.12994 61.61937 2.794993 1.254362 -0.05760508 26.708772 24.506707 25.904886 1.6701076 2.2647384 0.08001585 0.40543333 0.386175 0.419425 0.033250 8.698976e-01 9.504808e-07 FALSE  
ENST00000511802 ENSG00000145495 No_inf pgKDN_inf MARCHF6 protein_coding retained_intron 67.95121 64.12994 61.61937 2.794993 1.254362 -0.05760508 9.286640 12.419602 7.191172 0.4352172 0.7810945 -0.78747647 0.14368333 0.194425 0.116975 -0.077450 3.403210e-01 9.504808e-07 FALSE  
ENST00000514312 ENSG00000145495 No_inf pgKDN_inf MARCHF6 protein_coding retained_intron 67.95121 64.12994 61.61937 2.794993 1.254362 -0.05760508 6.655329 4.653486 0.000000 4.6534857 0.0000000 -8.86526489 0.06278333 0.064250 0.000000 -0.064250 8.526037e-01 9.504808e-07    
ENST00000514961 ENSG00000145495 No_inf pgKDN_inf MARCHF6 protein_coding retained_intron 67.95121 64.12994 61.61937 2.794993 1.254362 -0.05760508 1.126923 3.380768 0.000000 2.0244836 0.0000000 -8.40546833 0.01820833 0.054625 0.000000 -0.054625 5.077142e-01 9.504808e-07    
MSTRG.22699.2 ENSG00000145495 No_inf pgKDN_inf MARCHF6 protein_coding   67.95121 64.12994 61.61937 2.794993 1.254362 -0.05760508 1.958587 0.000000 4.072185 0.0000000 0.8528749 8.67319763 0.02790833 0.000000 0.065825 0.065825 9.504808e-07 9.504808e-07 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000145495 E001 0.2452102 0.0163816664 9.865317e-01   5 10353695 10353697 3 + 0.096 0.094 -0.020
ENSG00000145495 E002 0.3639133 0.2340190548 6.234895e-01   5 10353698 10353702 5 + 0.174 0.094 -1.021
ENSG00000145495 E003 1.0981917 0.4113976201 8.655674e-01 9.536934e-01 5 10353703 10353710 8 + 0.349 0.295 -0.345
ENSG00000145495 E004 1.4527203 0.0140090592 2.379962e-01 5.269546e-01 5 10353711 10353714 4 + 0.473 0.295 -1.020
ENSG00000145495 E005 1.5795743 0.0137049619 3.912272e-01 6.763722e-01 5 10353715 10353715 1 + 0.473 0.345 -0.698
ENSG00000145495 E006 16.0220236 0.0008729750 5.785077e-01 8.116444e-01 5 10353716 10353898 183 + 1.249 1.213 -0.130
ENSG00000145495 E007 12.2207719 0.0078146757 4.029347e-01 6.859811e-01 5 10353899 10353917 19 + 1.156 1.086 -0.252
ENSG00000145495 E008 0.0000000       5 10353968 10353996 29 +      
ENSG00000145495 E009 0.0000000       5 10354639 10354671 33 +      
ENSG00000145495 E010 23.0554121 0.0006083554 7.741017e-01 9.131846e-01 5 10377798 10377894 97 + 1.370 1.391 0.072
ENSG00000145495 E011 22.2764659 0.0157785577 8.968906e-01 9.659944e-01 5 10378759 10378832 74 + 1.370 1.364 -0.020
ENSG00000145495 E012 32.0158629 0.0004728654 3.021983e-01 5.953596e-01 5 10381800 10381943 144 + 1.544 1.493 -0.175
ENSG00000145495 E013 0.2447669 0.0163838948 9.866416e-01   5 10386925 10386993 69 + 0.096 0.094 -0.020
ENSG00000145495 E014 13.8059515 0.0032711833 4.556440e-01 7.280961e-01 5 10386994 10387066 73 + 1.198 1.142 -0.199
ENSG00000145495 E015 29.9021970 0.0004947400 7.026700e-02 2.681891e-01 5 10390332 10390500 169 + 1.433 1.535 0.350
ENSG00000145495 E016 40.9301621 0.0051937240 3.000682e-01 5.930166e-01 5 10391542 10391731 190 + 1.650 1.595 -0.184
ENSG00000145495 E017 31.9273082 0.0004777779 2.369466e-02 1.408030e-01 5 10394082 10394143 62 + 1.574 1.458 -0.397
ENSG00000145495 E018 25.8268822 0.0008711992 4.039452e-02 1.949390e-01 5 10394753 10394785 33 + 1.485 1.368 -0.404
ENSG00000145495 E019 0.3805619 0.5366767396 2.988300e-01   5 10397213 10397292 80 + 0.000 0.238 11.554
ENSG00000145495 E020 29.8410247 0.0005664907 1.699033e-02 1.138151e-01 5 10397293 10397344 52 + 1.550 1.424 -0.435
ENSG00000145495 E021 36.7587262 0.0008429930 2.633483e-03 3.127131e-02 5 10400784 10400842 59 + 1.647 1.500 -0.502
ENSG00000145495 E022 10.4434717 0.0014973809 2.938422e-04 5.711022e-03 5 10400843 10400932 90 + 0.855 1.186 1.219
ENSG00000145495 E023 44.1100934 0.0003344739 7.535334e-14 1.138405e-11 5 10400933 10401486 554 + 1.433 1.789 1.212
ENSG00000145495 E024 29.6313310 0.0251092500 6.280721e-06 2.285725e-04 5 10401487 10401856 370 + 1.231 1.634 1.392
ENSG00000145495 E025 21.7979544 0.0084668055 1.403013e-07 7.898760e-06 5 10401857 10402058 202 + 1.100 1.507 1.425
ENSG00000145495 E026 43.9395314 0.0226070628 3.870081e-02 1.903072e-01 5 10402059 10402139 81 + 1.724 1.574 -0.512
ENSG00000145495 E027 34.9895595 0.0004092815 1.837951e-02 1.198791e-01 5 10402384 10402452 69 + 1.612 1.497 -0.394
ENSG00000145495 E028 36.1727698 0.0006262576 2.240666e-01 5.116779e-01 5 10402533 10402607 75 + 1.599 1.541 -0.196
ENSG00000145495 E029 52.7083623 0.0008789146 7.287495e-01 8.918470e-01 5 10403407 10403541 135 + 1.720 1.738 0.060
ENSG00000145495 E030 48.3338944 0.0003405984 5.062585e-01 7.650047e-01 5 10405558 10405677 120 + 1.706 1.680 -0.086
ENSG00000145495 E031 43.1087027 0.0003166169 1.261708e-01 3.766312e-01 5 10407102 10407202 101 + 1.677 1.611 -0.225
ENSG00000145495 E032 17.5641627 0.0077417350 2.572270e-01 5.495293e-01 5 10410139 10410152 14 + 1.311 1.225 -0.301
ENSG00000145495 E033 54.4158842 0.0002988866 4.000990e-01 6.836253e-01 5 10410153 10410276 124 + 1.759 1.728 -0.105
ENSG00000145495 E034 88.7932676 0.0008403721 3.620048e-01 6.513047e-01 5 10411333 10411537 205 + 1.967 1.940 -0.092
ENSG00000145495 E035 1.0077768 0.0146325257 2.896060e-02 1.595303e-01 5 10413274 10413450 177 + 0.096 0.432 2.787
ENSG00000145495 E036 39.3404963 0.0003748101 1.926814e-01 4.724987e-01 5 10414433 10414502 70 + 1.635 1.576 -0.200
ENSG00000145495 E037 0.3806233 0.0158283275 1.072465e-01   5 10415473 10415487 15 + 0.000 0.238 12.795
ENSG00000145495 E038 58.9147342 0.0012735018 1.770569e-01 4.514650e-01 5 10415488 10415598 111 + 1.804 1.751 -0.176
ENSG00000145495 E039 49.1618754 0.0002940736 3.613178e-01 6.508101e-01 5 10415599 10415669 71 + 1.718 1.683 -0.121
ENSG00000145495 E040 64.9982080 0.0002677613 6.415387e-01 8.478203e-01 5 10417270 10417404 135 + 1.826 1.812 -0.047
ENSG00000145495 E041 0.7322322 0.4179213796 8.679927e-01 9.547298e-01 5 10417405 10417410 6 + 0.240 0.238 -0.020
ENSG00000145495 E042 0.3795211 0.5779557197 3.140460e-01   5 10417411 10417451 41 + 0.000 0.238 11.527
ENSG00000145495 E043 0.7521182 0.0141819145 9.839458e-02 3.272578e-01 5 10421931 10422036 106 + 0.096 0.345 2.302
ENSG00000145495 E044 47.4953723 0.0003145803 6.782584e-01 8.668041e-01 5 10423735 10423824 90 + 1.693 1.678 -0.050
ENSG00000145495 E045 0.2340080 0.2446090374 2.899606e-01   5 10423825 10423835 11 + 0.174 0.000 -11.952
ENSG00000145495 E046 66.9063958 0.0002313357 7.925906e-01 9.208578e-01 5 10426390 10426522 133 + 1.825 1.838 0.043
ENSG00000145495 E047 68.5916384 0.0008017046 1.131818e-02 8.726732e-02 5 10429893 10430028 136 + 1.887 1.796 -0.309
ENSG00000145495 E048 112.9344438 0.0001629344 4.566502e-02 2.092165e-01 5 10433594 10433928 335 + 2.083 2.030 -0.177
ENSG00000145495 E049 33.8387715 0.0006108750 7.644136e-01 9.083232e-01 5 10433929 10434207 279 + 1.532 1.550 0.063
ENSG00000145495 E050 331.9133556 0.0001357518 1.625497e-02 1.107688e-01 5 10434208 10436794 2587 + 2.500 2.541 0.137
ENSG00000145495 E051 211.3477792 0.0015584658 7.754317e-03 6.766330e-02 5 10436795 10440388 3594 + 2.289 2.358 0.232

Help

Please Click HERE to learn more details about the results from DEXseq.