ENSG00000145632

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000274289 ENSG00000145632 No_inf pgKDN_inf PLK2 protein_coding protein_coding 31.50011 73.89523 10.49023 5.067856 0.7007063 -2.815255 16.464116 40.16880 6.620408 1.254495 2.966673 -2.599265 0.5723417 0.548375 0.585900 0.037525 8.731775e-01 6.958752e-14 FALSE TRUE
ENST00000511326 ENSG00000145632 No_inf pgKDN_inf PLK2 protein_coding retained_intron 31.50011 73.89523 10.49023 5.067856 0.7007063 -2.815255 11.172299 26.00516 0.000000 3.666529 0.000000 -11.345137 0.2546583 0.346725 0.000000 -0.346725 6.958752e-14 6.958752e-14   FALSE
ENST00000617412 ENSG00000145632 No_inf pgKDN_inf PLK2 protein_coding protein_coding 31.50011 73.89523 10.49023 5.067856 0.7007063 -2.815255 1.199229 0.00000 3.597686 0.000000 2.112690 8.494930 0.1282083 0.000000 0.384625 0.384625 2.740023e-01 6.958752e-14 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000145632 E001 0.3805619 0.6462184684 1.0000000000   5 58453982 58453984 3 - 0.000 0.128 8.979
ENSG00000145632 E002 0.7534727 0.1916434951 1.0000000000 1.000000000 5 58453985 58453986 2 - 0.183 0.196 0.118
ENSG00000145632 E003 32.5224352 0.0310939076 0.4794520342 0.745187920 5 58453987 58454225 239 - 1.332 1.416 0.291
ENSG00000145632 E004 110.8885443 0.0001620961 0.0003072645 0.005916162 5 58454226 58454705 480 - 1.806 1.944 0.463
ENSG00000145632 E005 26.8196254 0.0014889100 0.0159354585 0.109471790 5 58454706 58454774 69 - 1.150 1.351 0.707
ENSG00000145632 E006 30.8686043 0.0004844665 0.5313445014 0.782006853 5 58454911 58454974 64 - 1.343 1.389 0.161
ENSG00000145632 E007 25.5725800 0.0110463399 0.9855170186 0.999020297 5 58454975 58455021 47 - 1.299 1.304 0.018
ENSG00000145632 E008 2.1493599 0.0066418311 0.1541961022 0.419491177 5 58455022 58455116 95 - 0.183 0.451 1.796
ENSG00000145632 E009 40.5562427 0.0007420329 0.2738860757 0.567621104 5 58455285 58455414 130 - 1.546 1.485 -0.210
ENSG00000145632 E010 30.9974910 0.0005044734 0.5113557129 0.768542591 5 58455539 58455610 72 - 1.343 1.391 0.168
ENSG00000145632 E011 47.2394858 0.0003683754 0.7724264124 0.912342804 5 58455611 58455779 169 - 1.571 1.558 -0.046
ENSG00000145632 E012 28.1909640 0.0004874401 0.7159835317 0.885495203 5 58456026 58456146 121 - 1.363 1.340 -0.081
ENSG00000145632 E013 10.2542151 0.0013915764 0.3335165791 0.625560819 5 58456147 58456155 9 - 1.019 0.919 -0.374
ENSG00000145632 E014 3.0396005 0.0087387452 0.0455349478 0.208797983 5 58456156 58456491 336 - 0.183 0.559 2.320
ENSG00000145632 E015 20.7579142 0.0175943060 0.3036776908 0.597060097 5 58456492 58456589 98 - 1.299 1.199 -0.352
ENSG00000145632 E016 0.7431172 0.1039530709 0.3670749028 0.655726429 5 58456743 58456944 202 - 0.312 0.163 -1.204
ENSG00000145632 E017 14.9908678 0.0017991139 0.1889761741 0.467575643 5 58456945 58457005 61 - 1.181 1.065 -0.420
ENSG00000145632 E018 18.0101462 0.0009390888 0.3408075328 0.632392261 5 58457006 58457060 55 - 1.224 1.146 -0.278
ENSG00000145632 E019 14.4767457 0.0009835323 0.0828001617 0.296549832 5 58457061 58457092 32 - 1.196 1.043 -0.552
ENSG00000145632 E020 24.9128176 0.0007065843 0.0010698836 0.015770183 5 58457181 58457308 128 - 1.468 1.247 -0.769
ENSG00000145632 E021 11.8592681 0.0160482171 0.1464871096 0.407564394 5 58457309 58457379 71 - 1.117 0.964 -0.558
ENSG00000145632 E022 0.5077596 0.0150646567 0.6907342055 0.873018269 5 58457380 58457421 42 - 0.000 0.163 12.021
ENSG00000145632 E023 4.6183184 0.0034485442 0.3178641862 0.610634677 5 58457488 58457493 6 - 0.758 0.623 -0.567
ENSG00000145632 E024 6.6445447 0.0025192343 0.8338751148 0.940155537 5 58457494 58457515 22 - 0.796 0.771 -0.100
ENSG00000145632 E025 10.6367271 0.0014787782 0.4203091338 0.699748369 5 58457516 58457579 64 - 1.019 0.937 -0.308
ENSG00000145632 E026 6.3805556 0.0079438848 0.5007799039 0.760797255 5 58457580 58457583 4 - 0.831 0.745 -0.341
ENSG00000145632 E027 0.2541163 0.0161655165 1.0000000000   5 58457584 58457737 154 - 0.000 0.089 11.082
ENSG00000145632 E028 11.6366145 0.0447401755 0.4777162660 0.743900635 5 58458084 58458171 88 - 1.061 0.970 -0.336
ENSG00000145632 E029 0.3801504 0.0263261356 1.0000000000   5 58458172 58458296 125 - 0.000 0.128 11.594
ENSG00000145632 E030 0.7610560 0.0173154539 0.3570910766 0.646829559 5 58458297 58458398 102 - 0.000 0.226 12.543
ENSG00000145632 E031 18.6559410 0.0008580855 0.5835635580 0.814711041 5 58458399 58458528 130 - 1.210 1.167 -0.155
ENSG00000145632 E032 0.5081680 0.0156590330 0.6922276406 0.874023507 5 58458529 58458724 196 - 0.000 0.163 12.019
ENSG00000145632 E033 19.1341364 0.0007357049 0.3119075241 0.605253666 5 58458725 58458841 117 - 1.251 1.170 -0.285
ENSG00000145632 E034 0.1272623 0.0124384731 0.8988073342   5 58458842 58458864 23 - 0.000 0.047 10.138
ENSG00000145632 E035 0.1265070 0.0123791329 0.8987946357   5 58458865 58458984 120 - 0.000 0.047 10.138
ENSG00000145632 E036 19.2745502 0.0007047608 0.4431277963 0.718225379 5 58458985 58459092 108 - 1.238 1.177 -0.216
ENSG00000145632 E037 0.5077596 0.0150646567 0.6907342055 0.873018269 5 58459093 58459505 413 - 0.000 0.163 12.021
ENSG00000145632 E038 13.0899633 0.0010238858 0.1418681818 0.400763914 5 58459690 58459755 66 - 0.894 1.056 0.603
ENSG00000145632 E039 8.6990356 0.0016223921 0.0767814467 0.283309198 5 58459756 58459797 42 - 0.670 0.907 0.943
ENSG00000145632 E040 16.4482521 0.0010830911 0.6005835665 0.825123521 5 58459798 58460139 342 - 1.080 1.132 0.185

Help

Please Click HERE to learn more details about the results from DEXseq.