ENSG00000145868

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000296701 ENSG00000145868 No_inf pgKDN_inf FBXO38 protein_coding protein_coding 30.31723 49.69896 23.4862 1.469076 1.276429 -1.081078 4.410157 4.154768 6.606983 1.4007412 0.9382806 0.6679372 0.1686333 0.084500 0.286550 0.202050 0.3095526 0.0235589 FALSE TRUE
ENST00000340253 ENSG00000145868 No_inf pgKDN_inf FBXO38 protein_coding protein_coding 30.31723 49.69896 23.4862 1.469076 1.276429 -1.081078 5.319412 6.655581 4.626301 1.0672590 0.6347066 -0.5237563 0.2000917 0.133750 0.196050 0.062300 0.7244399 0.0235589 FALSE TRUE
ENST00000508176 ENSG00000145868 No_inf pgKDN_inf FBXO38 protein_coding retained_intron 30.31723 49.69896 23.4862 1.469076 1.276429 -1.081078 1.150459 3.259545 0.000000 1.6071208 0.0000000 -8.3529462 0.0248000 0.063300 0.000000 -0.063300 0.1201252 0.0235589 FALSE FALSE
MSTRG.23745.18 ENSG00000145868 No_inf pgKDN_inf FBXO38 protein_coding   30.31723 49.69896 23.4862 1.469076 1.276429 -1.081078 3.511634 5.457091 2.927222 0.5951898 1.0120603 -0.8963209 0.1206417 0.109675 0.129175 0.019500 1.0000000 0.0235589 FALSE TRUE
MSTRG.23745.22 ENSG00000145868 No_inf pgKDN_inf FBXO38 protein_coding   30.31723 49.69896 23.4862 1.469076 1.276429 -1.081078 10.079721 22.214628 5.297919 1.0030016 0.9276023 -2.0659409 0.2731000 0.447675 0.223250 -0.224425 0.0235589 0.0235589 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000145868 E001 0.3549719 0.0162916590 3.182759e-02   5 148383935 148383951 17 + 0.296 0.000 -12.095
ENSG00000145868 E002 0.3549719 0.0162916590 3.182759e-02   5 148383952 148383957 6 + 0.296 0.000 -14.562
ENSG00000145868 E003 1.9494247 0.0175441626 1.112931e-01 3.503463e-01 5 148383958 148384001 44 + 0.594 0.360 -1.180
ENSG00000145868 E004 2.0681279 0.0087345716 6.075894e-02 2.474121e-01 5 148384002 148384008 7 + 0.628 0.360 -1.332
ENSG00000145868 E005 2.0681279 0.0087345716 6.075894e-02 2.474121e-01 5 148384009 148384009 1 + 0.628 0.360 -1.332
ENSG00000145868 E006 3.8068467 0.0086703920 3.097511e-01 6.030473e-01 5 148384010 148384039 30 + 0.744 0.616 -0.538
ENSG00000145868 E007 0.1268540 0.0122983935 1.000000e+00   5 148384764 148385106 343 + 0.000 0.073 11.085
ENSG00000145868 E008 0.1272623 0.0123124226 1.000000e+00   5 148394712 148394713 2 + 0.000 0.073 11.085
ENSG00000145868 E009 14.4479464 0.0286418491 7.583553e-01 9.051437e-01 5 148394714 148394904 191 + 1.184 1.160 -0.087
ENSG00000145868 E010 0.3798680 0.0222111739 2.718171e-01   5 148397619 148397676 58 + 0.000 0.191 12.551
ENSG00000145868 E011 0.0000000       5 148398997 148398998 2 +      
ENSG00000145868 E012 4.0927898 0.0059345897 7.472793e-01 9.002404e-01 5 148398999 148399014 16 + 0.660 0.704 0.182
ENSG00000145868 E013 8.7403021 0.0056320596 2.034311e-01 4.859748e-01 5 148399015 148399132 118 + 1.044 0.923 -0.450
ENSG00000145868 E014 0.2441403 0.0161027739 6.562491e-01   5 148399133 148399537 405 + 0.122 0.073 -0.818
ENSG00000145868 E015 9.8076929 0.0194705043 4.297244e-02 2.021346e-01 5 148401982 148402145 164 + 1.136 0.932 -0.746
ENSG00000145868 E016 9.3879425 0.0015151592 4.568153e-04 8.139371e-03 5 148402348 148402513 166 + 1.175 0.861 -1.156
ENSG00000145868 E017 0.0000000       5 148402514 148402565 52 +      
ENSG00000145868 E018 0.1176306 0.0116921326 2.936080e-01   5 148404684 148404684 1 + 0.122 0.000 -13.098
ENSG00000145868 E019 13.0535021 0.0038804361 2.385738e-04 4.833673e-03 5 148404685 148404822 138 + 1.298 1.001 -1.061
ENSG00000145868 E020 13.9038947 0.0010151336 1.116704e-01 3.510218e-01 5 148406257 148406394 138 + 1.228 1.107 -0.432
ENSG00000145868 E021 9.2046903 0.0213198757 7.255464e-02 2.733992e-01 5 148409124 148409217 94 + 1.104 0.913 -0.703
ENSG00000145868 E022 0.0000000       5 148409218 148409220 3 +      
ENSG00000145868 E023 0.8784392 0.2110418510 3.093272e-01 6.027404e-01 5 148410238 148410485 248 + 0.122 0.323 1.766
ENSG00000145868 E024 11.4780300 0.0427691107 7.348019e-03 6.523589e-02 5 148410635 148410765 131 + 1.245 0.951 -1.064
ENSG00000145868 E025 0.5982683 0.0194319794 4.784730e-02 2.152111e-01 5 148410766 148410868 103 + 0.362 0.073 -2.818
ENSG00000145868 E026 0.7341784 0.0134504330 4.900146e-01 7.527542e-01 5 148413187 148413239 53 + 0.296 0.191 -0.818
ENSG00000145868 E027 8.2063715 0.0048744161 2.226154e-01 5.099653e-01 5 148413240 148414135 896 + 0.856 0.985 0.489
ENSG00000145868 E028 14.5327367 0.0028607967 2.686414e-04 5.317030e-03 5 148414136 148414306 171 + 1.332 1.054 -0.987
ENSG00000145868 E029 1.1245257 0.0106724503 3.732715e-01 6.609983e-01 5 148415249 148415359 111 + 0.217 0.360 0.990
ENSG00000145868 E030 0.4995438 0.0156678169 6.679638e-01   5 148415360 148415387 28 + 0.122 0.191 0.767
ENSG00000145868 E031 10.7203193 0.0498930227 5.903028e-01 8.186857e-01 5 148415928 148416070 143 + 1.092 1.025 -0.246
ENSG00000145868 E032 0.3812526 0.0164339228 2.698120e-01   5 148416637 148416688 52 + 0.000 0.191 12.572
ENSG00000145868 E033 21.6954995 0.0006046213 1.827521e-01 4.593202e-01 5 148416994 148417204 211 + 1.387 1.305 -0.287
ENSG00000145868 E034 0.2533610 0.0159596392 5.109080e-01   5 148417205 148417215 11 + 0.000 0.136 12.026
ENSG00000145868 E035 0.0000000       5 148423749 148423997 249 +      
ENSG00000145868 E036 12.7629239 0.0012759633 1.270856e-02 9.385508e-02 5 148423998 148424117 120 + 1.237 1.040 -0.707
ENSG00000145868 E037 21.0036346 0.0007093231 5.563456e-01 7.986464e-01 5 148425522 148425701 180 + 1.345 1.309 -0.126
ENSG00000145868 E038 0.3703650 0.0164502615 1.000000e+00   5 148427210 148427212 3 + 0.122 0.136 0.182
ENSG00000145868 E039 28.0709420 0.0034173033 8.836968e-01 9.609283e-01 5 148427213 148427622 410 + 1.447 1.440 -0.023
ENSG00000145868 E040 11.3790257 0.0081116826 8.738154e-01 9.569172e-01 5 148427623 148427722 100 + 1.081 1.068 -0.047
ENSG00000145868 E041 13.8612928 0.0009982103 9.375255e-01 9.820871e-01 5 148427723 148427947 225 + 1.146 1.155 0.030
ENSG00000145868 E042 8.4039333 0.0016655604 3.919547e-04 7.179893e-03 5 148428063 148428451 389 + 0.660 1.054 1.530
ENSG00000145868 E043 2.5011893 0.0056508716 1.204614e-01 3.671511e-01 5 148433233 148433423 191 + 0.362 0.597 1.182
ENSG00000145868 E044 21.5137374 0.0040400993 7.417393e-01 8.976768e-01 5 148433424 148433524 101 + 1.345 1.324 -0.072
ENSG00000145868 E045 18.3938136 0.0099736716 5.301180e-01 7.813335e-01 5 148433635 148433737 103 + 1.298 1.250 -0.168
ENSG00000145868 E046 9.0481660 0.0723983189 1.967974e-03 2.525356e-02 5 148433738 148435058 1321 + 0.628 1.095 1.816
ENSG00000145868 E047 37.5888673 0.0003990934 8.702365e-01 9.552531e-01 5 148438332 148438498 167 + 1.569 1.563 -0.020
ENSG00000145868 E048 42.9150453 0.0048617699 8.537617e-01 9.484189e-01 5 148439647 148439792 146 + 1.626 1.619 -0.025
ENSG00000145868 E049 1.0050400 0.0117536341 1.386004e-01 3.958904e-01 5 148440356 148440423 68 + 0.122 0.360 1.990
ENSG00000145868 E050 36.6074361 0.0018543279 9.294541e-01 9.792577e-01 5 148440424 148440527 104 + 1.550 1.557 0.024
ENSG00000145868 E051 39.7509322 0.0004495607 4.944905e-01 7.559605e-01 5 148441124 148441237 114 + 1.565 1.601 0.122
ENSG00000145868 E052 2.3767596 0.0058290724 1.590495e-01 4.262449e-01 5 148441238 148441502 265 + 0.362 0.576 1.089
ENSG00000145868 E053 173.5891040 0.0011192456 5.654682e-11 5.887638e-09 5 148441969 148442836 868 + 2.109 2.269 0.538

Help

Please Click HERE to learn more details about the results from DEXseq.