ENSG00000145882

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000274569 ENSG00000145882 No_inf pgKDN_inf PCYOX1L protein_coding protein_coding 28.52094 29.37176 29.2437 0.8601265 1.107352 -0.006301328 20.231666 25.8440334 18.752502 1.2391358 1.5247828 -0.4625371 0.70438333 0.878525 0.645925 -0.23260 0.008526817 0.004235328 FALSE TRUE
ENST00000511945 ENSG00000145882 No_inf pgKDN_inf PCYOX1L protein_coding nonsense_mediated_decay 28.52094 29.37176 29.2437 0.8601265 1.107352 -0.006301328 2.028268 0.0000000 1.911456 0.0000000 1.9114561 7.5860562 0.07464167 0.000000 0.061100 0.06110 0.842059993 0.004235328 FALSE TRUE
MSTRG.23733.1 ENSG00000145882 No_inf pgKDN_inf PCYOX1L protein_coding   28.52094 29.37176 29.2437 0.8601265 1.107352 -0.006301328 4.050744 0.5374296 7.540125 0.5374296 0.5677567 3.7857551 0.14285000 0.019900 0.257950 0.23805 0.004235328 0.004235328 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000145882 E001 0.6008724 1.492495e-02 0.1174899634 0.362097353 5 149358018 149358036 19 + 0.317 0.087 -2.268
ENSG00000145882 E002 1.0717757 1.113265e-02 0.0065518427 0.060178318 5 149358037 149358045 9 + 0.498 0.087 -3.269
ENSG00000145882 E003 2.0497136 1.891241e-02 0.0430103148 0.202261247 5 149358046 149358068 23 + 0.626 0.325 -1.532
ENSG00000145882 E004 4.0020101 4.023053e-03 0.0367105031 0.184438218 5 149358069 149358156 88 + 0.822 0.565 -1.076
ENSG00000145882 E005 0.0000000       5 149358157 149358172 16 +      
ENSG00000145882 E006 3.3725509 2.985973e-02 0.0223906131 0.136073270 5 149362053 149362239 187 + 0.417 0.755 1.539
ENSG00000145882 E007 3.5018880 4.897560e-03 0.0091555807 0.075863448 5 149362240 149362636 397 + 0.417 0.771 1.606
ENSG00000145882 E008 16.1220701 8.837017e-04 0.6774809577 0.866351906 5 149362637 149362843 207 + 1.213 1.243 0.108
ENSG00000145882 E009 1.1324587 1.552427e-02 0.0287977355 0.159005572 5 149362844 149362966 123 + 0.103 0.445 2.731
ENSG00000145882 E010 1.2504363 1.018732e-02 0.0968563331 0.324139396 5 149362967 149363016 50 + 0.187 0.445 1.731
ENSG00000145882 E011 2.1386629 6.742220e-03 0.0030418317 0.034876308 5 149363017 149363068 52 + 0.187 0.638 2.638
ENSG00000145882 E012 7.9830261 2.846923e-03 0.0008962164 0.013778944 5 149363069 149364035 967 + 0.724 1.068 1.316
ENSG00000145882 E013 22.5973192 6.552457e-04 0.0234027615 0.139745754 5 149364036 149364210 175 + 1.441 1.305 -0.472
ENSG00000145882 E014 6.5033095 2.079986e-03 0.0002950241 0.005727801 5 149364211 149365941 1731 + 0.597 1.006 1.629
ENSG00000145882 E015 28.6125049 4.966768e-04 0.7431154013 0.898394941 5 149365942 149366118 177 + 1.477 1.461 -0.058
ENSG00000145882 E016 13.4254646 1.142729e-03 0.5133011748 0.770165959 5 149366119 149366153 35 + 1.126 1.178 0.185
ENSG00000145882 E017 28.8528936 5.020902e-04 0.7359194990 0.895213530 5 149367360 149367500 141 + 1.481 1.464 -0.060
ENSG00000145882 E018 6.9970124 2.313684e-03 0.7588249279 0.905372002 5 149367993 149367994 2 + 0.917 0.886 -0.117
ENSG00000145882 E019 280.5164921 9.599632e-05 0.1985596053 0.479992549 5 149367995 149369653 1659 + 2.453 2.440 -0.043

Help

Please Click HERE to learn more details about the results from DEXseq.