ENSG00000146463

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000314607 ENSG00000146463 No_inf pgKDN_inf ZMYM4 protein_coding protein_coding 16.04575 14.57155 16.93268 0.6236177 0.6652825 0.2165173 2.0176070 3.0744107 1.507823 1.2347243 1.5078227 -1.0229916 0.12792500 0.217200 0.089450 -0.127750 0.40471136 0.04218986 FALSE TRUE
ENST00000457946 ENSG00000146463 No_inf pgKDN_inf ZMYM4 protein_coding protein_coding 16.04575 14.57155 16.93268 0.6236177 0.6652825 0.2165173 0.5860757 0.0000000 1.758227 0.0000000 1.0534303 7.4661597 0.03364167 0.000000 0.100925 0.100925 0.48990691 0.04218986 FALSE TRUE
MSTRG.693.1 ENSG00000146463 No_inf pgKDN_inf ZMYM4 protein_coding   16.04575 14.57155 16.93268 0.6236177 0.6652825 0.2165173 2.6614737 0.3059144 3.591015 0.3059144 1.3208939 3.5107979 0.16327500 0.020325 0.215275 0.194950 0.27001311 0.04218986 FALSE TRUE
MSTRG.693.11 ENSG00000146463 No_inf pgKDN_inf ZMYM4 protein_coding   16.04575 14.57155 16.93268 0.6236177 0.6652825 0.2165173 4.9675873 6.7131161 4.676252 0.5258633 0.5695051 -0.5206954 0.31435000 0.458975 0.278250 -0.180725 0.33914014 0.04218986 FALSE TRUE
MSTRG.693.4 ENSG00000146463 No_inf pgKDN_inf ZMYM4 protein_coding   16.04575 14.57155 16.93268 0.6236177 0.6652825 0.2165173 1.3019188 0.6856900 3.220066 0.6856900 1.3331814 2.2150473 0.07807500 0.042575 0.191650 0.149075 0.40577808 0.04218986 FALSE TRUE
MSTRG.693.6 ENSG00000146463 No_inf pgKDN_inf ZMYM4 protein_coding   16.04575 14.57155 16.93268 0.6236177 0.6652825 0.2165173 2.0861150 1.6251843 1.168513 0.9674350 1.1685130 -0.4724856 0.13638333 0.113375 0.069325 -0.044050 0.81852632 0.04218986 FALSE TRUE
MSTRG.693.9 ENSG00000146463 No_inf pgKDN_inf ZMYM4 protein_coding   16.04575 14.57155 16.93268 0.6236177 0.6652825 0.2165173 0.9104010 1.6712385 0.000000 0.6116688 0.0000000 -7.3933806 0.05607500 0.111150 0.000000 -0.111150 0.04218986 0.04218986 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000146463 E001 0.1186381 0.0118115410 7.011881e-01   1 35268688 35268708 21 + 0.084 0.000 -9.829
ENSG00000146463 E002 0.1186381 0.0118115410 7.011881e-01   1 35268709 35268710 2 + 0.084 0.000 -12.164
ENSG00000146463 E003 1.8140815 0.0074995366 4.316051e-01 7.093248e-01 1 35268711 35268971 261 + 0.498 0.379 -0.620
ENSG00000146463 E004 1.2057486 0.0108781709 3.898978e-01 6.754055e-01 1 35268972 35269032 61 + 0.398 0.264 -0.842
ENSG00000146463 E005 1.5554674 0.0094789138 3.236897e-02 1.703540e-01 1 35269033 35269085 53 + 0.526 0.193 -2.080
ENSG00000146463 E006 0.3561095 0.5403871679 3.908111e-01   1 35269086 35269089 4 + 0.216 0.000 -12.847
ENSG00000146463 E007 0.1272623 0.0123623062 4.104070e-01   1 35269228 35269258 31 + 0.000 0.107 11.712
ENSG00000146463 E008 0.0000000       1 35284673 35284706 34 +      
ENSG00000146463 E009 1.1009542 0.0894667364 9.583985e-01 9.900487e-01 1 35295927 35295988 62 + 0.317 0.326 0.058
ENSG00000146463 E010 0.8447954 0.0125811507 4.236497e-01 7.028860e-01 1 35325360 35325405 46 + 0.317 0.193 -0.942
ENSG00000146463 E011 8.5340409 0.0034454850 7.985008e-04 1.258882e-02 1 35358925 35359446 522 + 1.100 0.759 -1.288
ENSG00000146463 E012 4.2342993 0.0102785231 1.640358e-01 4.331933e-01 1 35361194 35361255 62 + 0.789 0.610 -0.746
ENSG00000146463 E013 4.1302602 0.0037061426 5.473032e-01 7.927554e-01 1 35361619 35361704 86 + 0.741 0.666 -0.312
ENSG00000146463 E014 1.5804548 0.0488857973 7.340652e-01 8.944097e-01 1 35361705 35361716 12 + 0.434 0.379 -0.298
ENSG00000146463 E015 3.6486526 0.0042124154 7.108467e-01 8.831060e-01 1 35361717 35361789 73 + 0.687 0.639 -0.205
ENSG00000146463 E016 4.5188468 0.0035615637 7.547778e-01 9.035422e-01 1 35370029 35370113 85 + 0.724 0.759 0.145
ENSG00000146463 E017 9.3881475 0.0142284418 9.013294e-01 9.681796e-01 1 35370372 35370627 256 + 1.010 1.021 0.041
ENSG00000146463 E018 0.2457744 0.0162800367 8.361347e-01   1 35370628 35370880 253 + 0.084 0.107 0.380
ENSG00000146463 E019 9.2566021 0.0099113291 8.261086e-01 9.370213e-01 1 35381259 35381433 175 + 1.019 0.997 -0.080
ENSG00000146463 E020 1.8130402 0.0081678367 4.313206e-01 7.090169e-01 1 35381546 35381547 2 + 0.498 0.379 -0.620
ENSG00000146463 E021 12.1072820 0.0123197259 1.264010e-01 3.768691e-01 1 35381548 35381758 211 + 1.175 1.032 -0.513
ENSG00000146463 E022 9.4091602 0.0105774521 1.860947e-02 1.209548e-01 1 35385442 35385592 151 + 1.107 0.870 -0.878
ENSG00000146463 E023 7.5375352 0.0224763169 6.331649e-01 8.429799e-01 1 35386074 35386189 116 + 0.951 0.902 -0.186
ENSG00000146463 E024 14.4670184 0.0009429049 4.994084e-01 7.596123e-01 1 35387003 35387278 276 + 1.210 1.158 -0.185
ENSG00000146463 E025 9.3837186 0.0014395837 9.263067e-01 9.778656e-01 1 35387454 35387604 151 + 1.019 1.009 -0.035
ENSG00000146463 E026 14.2428281 0.0009466174 7.414159e-01 8.974667e-01 1 35388910 35389082 173 + 1.193 1.167 -0.093
ENSG00000146463 E027 16.5103227 0.0063139441 3.023439e-01 5.954677e-01 1 35389948 35390098 151 + 1.205 1.282 0.273
ENSG00000146463 E028 11.6573686 0.0073835944 4.759841e-01 7.426228e-01 1 35392212 35392352 141 + 1.129 1.065 -0.230
ENSG00000146463 E029 5.3704481 0.0613063996 7.718818e-01 9.121858e-01 1 35392647 35392679 33 + 0.789 0.819 0.117
ENSG00000146463 E030 3.7929853 0.1643352520 6.365944e-01 8.448856e-01 1 35392680 35392684 5 + 0.647 0.715 0.288
ENSG00000146463 E031 12.3891070 0.0011303129 6.692937e-02 2.607649e-01 1 35393595 35393739 145 + 1.053 1.199 0.523
ENSG00000146463 E032 5.0400225 0.0161160589 1.255549e-01 3.755667e-01 1 35396552 35396554 3 + 0.687 0.871 0.734
ENSG00000146463 E033 7.4555410 0.0021264911 5.165726e-01 7.722985e-01 1 35396555 35396670 116 + 0.896 0.959 0.238
ENSG00000146463 E034 0.2452102 0.0162735164 8.366125e-01   1 35397052 35397123 72 + 0.084 0.107 0.380
ENSG00000146463 E035 0.0000000       1 35397377 35397545 169 +      
ENSG00000146463 E036 2.7831771 0.0531131091 2.669901e-01 5.602398e-01 1 35398413 35398466 54 + 0.647 0.470 -0.813
ENSG00000146463 E037 13.1369949 0.0011010380 6.205020e-04 1.029728e-02 1 35398864 35399043 180 + 1.254 0.972 -1.017
ENSG00000146463 E038 6.8739323 0.0071061408 2.178368e-02 1.339575e-01 1 35399482 35399576 95 + 0.991 0.738 -0.978
ENSG00000146463 E039 0.1176306 0.0117731407 7.010695e-01   1 35404290 35404338 49 + 0.084 0.000 -12.164
ENSG00000146463 E040 0.1271363 0.0123039076 4.104635e-01   1 35404844 35405022 179 + 0.000 0.107 11.712
ENSG00000146463 E041 11.4477957 0.0024050315 7.149020e-01 8.850940e-01 1 35405023 35405194 172 + 1.107 1.075 -0.116
ENSG00000146463 E042 9.1699216 0.0036841163 5.736520e-01 8.089792e-01 1 35405373 35405468 96 + 0.982 1.032 0.187
ENSG00000146463 E043 16.4853271 0.0043148829 6.825563e-01 8.685848e-01 1 35408008 35408159 152 + 1.227 1.256 0.101
ENSG00000146463 E044 14.8897749 0.0143302520 7.399249e-01 8.968699e-01 1 35413972 35414083 112 + 1.187 1.214 0.095
ENSG00000146463 E045 25.4968311 0.0009612886 1.555808e-01 4.215024e-01 1 35415466 35415714 249 + 1.458 1.373 -0.291
ENSG00000146463 E046 19.0726939 0.0048168249 4.358032e-01 7.122678e-01 1 35418443 35418572 130 + 1.326 1.269 -0.197
ENSG00000146463 E047 182.7240913 0.0001860998 1.381862e-06 6.159451e-05 1 35419470 35422058 2589 + 2.221 2.307 0.287

Help

Please Click HERE to learn more details about the results from DEXseq.