ENSG00000146826

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000316937 ENSG00000146826 No_inf pgKDN_inf TRAPPC14 protein_coding protein_coding 23.30707 34.72706 14.86906 1.953966 1.220774 -1.223192 5.6776508 7.0794140 3.4641973 1.0341346 1.1708667 -1.028987 0.26195000 0.206450 0.244375 0.037925 1.000000000 0.004120778 FALSE TRUE
ENST00000394035 ENSG00000146826 No_inf pgKDN_inf TRAPPC14 protein_coding nonsense_mediated_decay 23.30707 34.72706 14.86906 1.953966 1.220774 -1.223192 3.1058887 4.1203930 1.5446478 1.4408573 0.5732382 -1.409691 0.13240833 0.121450 0.104775 -0.016675 1.000000000 0.004120778 FALSE TRUE
ENST00000456769 ENSG00000146826 No_inf pgKDN_inf TRAPPC14 protein_coding protein_coding 23.30707 34.72706 14.86906 1.953966 1.220774 -1.223192 1.2879424 0.0000000 3.8638273 0.0000000 1.4932859 8.597616 0.08570833 0.000000 0.257125 0.257125 0.004120778 0.004120778 FALSE TRUE
ENST00000457641 ENSG00000146826 No_inf pgKDN_inf TRAPPC14 protein_coding protein_coding 23.30707 34.72706 14.86906 1.953966 1.220774 -1.223192 6.0199923 10.6586970 2.5281529 0.4803481 2.0522775 -2.071533 0.24480833 0.311450 0.172025 -0.139425 0.438390469 0.004120778 FALSE TRUE
ENST00000472061 ENSG00000146826 No_inf pgKDN_inf TRAPPC14 protein_coding retained_intron 23.30707 34.72706 14.86906 1.953966 1.220774 -1.223192 2.4989961 5.9869950 0.5860596 1.6398546 0.5860596 -3.330711 0.07842500 0.167025 0.033150 -0.133875 0.140856728 0.004120778 FALSE FALSE
ENST00000498638 ENSG00000146826 No_inf pgKDN_inf TRAPPC14 protein_coding retained_intron 23.30707 34.72706 14.86906 1.953966 1.220774 -1.223192 3.4773387 5.6419651 1.3095619 1.0300841 0.8108363 -2.098694 0.13818333 0.160250 0.087825 -0.072425 0.617497035 0.004120778 FALSE TRUE
MSTRG.26589.7 ENSG00000146826 No_inf pgKDN_inf TRAPPC14 protein_coding   23.30707 34.72706 14.86906 1.953966 1.220774 -1.223192 0.3947762 0.1048698 1.0794587 0.1048698 1.0794587 3.245540 0.02434167 0.002825 0.070200 0.067375 0.859500146 0.004120778 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000146826 E001 0.1186381 0.0119155119 0.245367711   7 100154420 100154422 3 - 0.131 0.000 -9.696
ENSG00000146826 E002 0.1186381 0.0119155119 0.245367711   7 100154423 100154423 1 - 0.131 0.000 -12.257
ENSG00000146826 E003 2.6148259 0.0206604996 0.702078269 0.87884059 7 100154424 100154458 35 - 0.493 0.551 0.275
ENSG00000146826 E004 6.0443544 0.0023440074 0.231633383 0.52032132 7 100154459 100154474 16 - 0.905 0.774 -0.511
ENSG00000146826 E005 37.5942467 0.0004425808 0.797885755 0.92384314 7 100154475 100154823 349 - 1.546 1.557 0.040
ENSG00000146826 E006 35.8913173 0.0004528384 0.390700197 0.67612657 7 100154824 100155164 341 - 1.505 1.547 0.145
ENSG00000146826 E007 18.1173239 0.0008635661 0.902748695 0.96886466 7 100155262 100155446 185 - 1.244 1.252 0.028
ENSG00000146826 E008 0.9989031 0.1316028397 0.698232418 0.87685909 7 100155447 100155455 9 - 0.231 0.306 0.539
ENSG00000146826 E009 1.2344816 0.0124009894 0.630642918 0.84150034 7 100155456 100155670 215 - 0.382 0.306 -0.462
ENSG00000146826 E010 0.0000000       7 100155671 100155825 155 -      
ENSG00000146826 E011 0.0000000       7 100155826 100155919 94 -      
ENSG00000146826 E012 0.0000000       7 100155920 100155931 12 -      
ENSG00000146826 E013 3.2468580 0.0060526431 0.287121564 0.58049744 7 100156265 100156385 121 - 0.493 0.644 0.690
ENSG00000146826 E014 17.0809217 0.0009272108 0.468136704 0.73643268 7 100156386 100156549 164 - 1.261 1.208 -0.186
ENSG00000146826 E015 0.0000000       7 100156605 100156633 29 -      
ENSG00000146826 E016 14.7806076 0.0009475041 0.567112596 0.80496965 7 100156634 100156716 83 - 1.136 1.180 0.158
ENSG00000146826 E017 14.6783078 0.0010024093 0.262644952 0.55544418 7 100156845 100156938 94 - 1.101 1.190 0.318
ENSG00000146826 E018 11.5573669 0.0149611822 0.643790051 0.84907743 7 100156939 100156992 54 - 1.035 1.082 0.168
ENSG00000146826 E019 1.5150667 0.0090416296 0.046467403 0.21154494 7 100156993 100156996 4 - 0.131 0.458 2.413
ENSG00000146826 E020 1.1349778 0.0108635137 0.136778544 0.39365069 7 100156997 100157093 97 - 0.131 0.373 1.953
ENSG00000146826 E021 16.7211432 0.0009061483 0.585718879 0.81611409 7 100157094 100157214 121 - 1.244 1.204 -0.142
ENSG00000146826 E022 0.0000000       7 100157293 100157372 80 -      
ENSG00000146826 E023 12.5955011 0.0015991862 0.161382409 0.42940300 7 100157373 100157459 87 - 1.178 1.063 -0.414
ENSG00000146826 E024 16.1679913 0.0009028424 0.122580169 0.37052283 7 100157633 100157762 130 - 1.277 1.165 -0.397
ENSG00000146826 E025 0.2448930 0.0162799648 0.571226302   7 100157763 100157842 80 - 0.131 0.068 -1.047
ENSG00000146826 E026 10.2168890 0.0018199387 0.250957525 0.54212133 7 100157843 100157938 96 - 0.941 1.050 0.401
ENSG00000146826 E027 5.2806282 0.0027800479 0.006482416 0.05965238 7 100157939 100158020 82 - 0.493 0.853 1.538
ENSG00000146826 E028 16.4707252 0.0008880410 0.626686328 0.83966066 7 100158089 100158588 500 - 1.235 1.199 -0.127
ENSG00000146826 E029 5.1224551 0.0079639265 0.001502629 0.02051716 7 100158589 100158723 135 - 0.975 0.609 -1.462

Help

Please Click HERE to learn more details about the results from DEXseq.