ENSG00000146828

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000354161 ENSG00000146828 No_inf pgKDN_inf SLC12A9 protein_coding protein_coding 31.11554 24.88049 30.32694 1.412617 1.349319 0.2854808 4.933870 2.542636 7.096690 1.7942960 0.8154035 1.477190 0.16110000 0.104100 0.233200 0.129100 0.38930667 0.02175982 FALSE TRUE
ENST00000467972 ENSG00000146828 No_inf pgKDN_inf SLC12A9 protein_coding retained_intron 31.11554 24.88049 30.32694 1.412617 1.349319 0.2854808 1.924711 3.264740 1.120463 0.3998258 0.2490550 -1.534467 0.06847500 0.130875 0.037375 -0.093500 0.11359940 0.02175982 FALSE TRUE
ENST00000475687 ENSG00000146828 No_inf pgKDN_inf SLC12A9 protein_coding retained_intron 31.11554 24.88049 30.32694 1.412617 1.349319 0.2854808 5.121776 7.539099 2.993690 0.5654026 0.4344568 -1.329568 0.17851667 0.304975 0.100825 -0.204150 0.02175982 0.02175982 FALSE TRUE
MSTRG.26613.10 ENSG00000146828 No_inf pgKDN_inf SLC12A9 protein_coding   31.11554 24.88049 30.32694 1.412617 1.349319 0.2854808 2.538135 1.115494 4.005253 1.1154944 4.0052535 1.834932 0.07934167 0.048075 0.118775 0.070700 1.00000000 0.02175982 FALSE TRUE
MSTRG.26613.14 ENSG00000146828 No_inf pgKDN_inf SLC12A9 protein_coding   31.11554 24.88049 30.32694 1.412617 1.349319 0.2854808 1.247781 0.000000 1.471482 0.0000000 1.4714818 7.210897 0.03305833 0.000000 0.051775 0.051775 0.86018660 0.02175982 FALSE TRUE
MSTRG.26613.5 ENSG00000146828 No_inf pgKDN_inf SLC12A9 protein_coding   31.11554 24.88049 30.32694 1.412617 1.349319 0.2854808 3.475555 4.433344 1.349876 1.2112190 1.3498761 -1.708171 0.11475000 0.182200 0.047500 -0.134700 0.09358571 0.02175982 FALSE TRUE
MSTRG.26613.6 ENSG00000146828 No_inf pgKDN_inf SLC12A9 protein_coding   31.11554 24.88049 30.32694 1.412617 1.349319 0.2854808 2.195537 1.149007 5.437603 1.1490067 3.4089066 2.232733 0.07320000 0.039525 0.180075 0.140550 0.81230904 0.02175982 FALSE TRUE
MSTRG.26613.9 ENSG00000146828 No_inf pgKDN_inf SLC12A9 protein_coding   31.11554 24.88049 30.32694 1.412617 1.349319 0.2854808 5.029753 1.172048 3.402319 1.1720477 3.4023189 1.529464 0.15400000 0.048700 0.121875 0.073175 1.00000000 0.02175982 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000146828 E001 0.0000000       7 100826820 100827047 228 +      
ENSG00000146828 E002 0.1176306 0.0117397423 4.940324e-01   7 100852713 100852718 6 + 0.098 0.000 -10.169
ENSG00000146828 E003 0.1176306 0.0117397423 4.940324e-01   7 100852719 100852719 1 + 0.098 0.000 -12.552
ENSG00000146828 E004 0.1176306 0.0117397423 4.940324e-01   7 100852720 100852721 2 + 0.098 0.000 -12.552
ENSG00000146828 E005 0.1176306 0.0117397423 4.940324e-01   7 100852722 100852722 1 + 0.098 0.000 -12.552
ENSG00000146828 E006 0.3634701 0.0164877876 5.315988e-01   7 100852723 100852732 10 + 0.178 0.092 -1.102
ENSG00000146828 E007 0.3634701 0.0164877876 5.315988e-01   7 100852733 100852736 4 + 0.178 0.092 -1.102
ENSG00000146828 E008 0.4821082 0.0152941146 2.795716e-01   7 100852737 100852741 5 + 0.246 0.092 -1.687
ENSG00000146828 E009 0.6089622 0.0147468203 5.891961e-01 8.178708e-01 7 100852742 100852745 4 + 0.246 0.168 -0.687
ENSG00000146828 E010 2.0701418 0.0069088420 3.707723e-01 6.589885e-01 7 100852746 100852776 31 + 0.548 0.424 -0.616
ENSG00000146828 E011 3.1851618 0.0052052296 8.295359e-01 9.382445e-01 7 100852777 100852835 59 + 0.633 0.610 -0.102
ENSG00000146828 E012 0.6251079 0.0149269362 2.040689e-01 4.867653e-01 7 100852836 100852839 4 + 0.098 0.289 1.898
ENSG00000146828 E013 0.2543986 0.0159926417 2.730956e-01   7 100853286 100853446 161 + 0.000 0.168 12.590
ENSG00000146828 E014 2.9841815 0.0048915654 6.519175e-02 2.570589e-01 7 100854156 100854277 122 + 0.443 0.700 1.178
ENSG00000146828 E015 7.2140323 0.0018554734 4.744901e-01 7.412290e-01 7 100854278 100854378 101 + 0.947 0.882 -0.249
ENSG00000146828 E016 16.0835047 0.0009772238 3.966756e-02 1.930578e-01 7 100854620 100854754 135 + 1.301 1.160 -0.498
ENSG00000146828 E017 6.0477865 0.0052327773 2.125798e-01 4.977330e-01 7 100855441 100855705 265 + 0.765 0.908 0.557
ENSG00000146828 E018 16.1356168 0.0009895467 2.354886e-01 5.248281e-01 7 100855706 100855837 132 + 1.273 1.195 -0.277
ENSG00000146828 E019 31.1349511 0.0006214947 6.534096e-12 7.644468e-10 7 100855838 100856793 956 + 1.255 1.646 1.348
ENSG00000146828 E020 4.2473572 0.0546356962 1.753507e-02 1.161770e-01 7 100856794 100856867 74 + 0.481 0.854 1.599
ENSG00000146828 E021 26.7280936 0.0005887655 7.152513e-01 8.852760e-01 7 100856868 100857029 162 + 1.449 1.435 -0.049
ENSG00000146828 E022 29.1290217 0.0054237997 2.847018e-01 5.784334e-01 7 100857030 100857176 147 + 1.508 1.450 -0.199
ENSG00000146828 E023 18.1171266 0.0120397813 3.352283e-08 2.157542e-06 7 100857177 100858735 1559 + 0.960 1.442 1.718
ENSG00000146828 E024 1.6322207 0.0094437963 1.461603e-02 1.032348e-01 7 100858736 100858834 99 + 0.178 0.556 2.358
ENSG00000146828 E025 22.2303822 0.0010594681 1.070550e-01 3.428889e-01 7 100858835 100858942 108 + 1.412 1.319 -0.324
ENSG00000146828 E026 0.2541163 0.0160128381 2.729940e-01   7 100858943 100859036 94 + 0.000 0.168 12.590
ENSG00000146828 E027 0.1272623 0.0123294616 5.856234e-01   7 100859037 100859049 13 + 0.000 0.092 11.651
ENSG00000146828 E028 24.5983797 0.0006302517 3.950139e-03 4.207085e-02 7 100859050 100859161 112 + 1.487 1.324 -0.563
ENSG00000146828 E029 1.4775165 0.0089996635 6.703423e-01 8.630389e-01 7 100859162 100859884 723 + 0.356 0.424 0.384
ENSG00000146828 E030 32.1045920 0.0004427036 5.631905e-01 8.026715e-01 7 100859885 100860042 158 + 1.531 1.508 -0.080
ENSG00000146828 E031 0.1265070 0.0123213755 5.855178e-01   7 100860043 100860149 107 + 0.000 0.092 11.651
ENSG00000146828 E032 19.9118692 0.0015133467 5.833486e-01 8.145073e-01 7 100860150 100860232 83 + 1.296 1.338 0.148
ENSG00000146828 E033 4.6282053 0.1082160140 1.290907e-02 9.488114e-02 7 100860233 100860516 284 + 0.481 0.895 1.756
ENSG00000146828 E034 6.4955056 0.0717027115 1.066610e-02 8.377857e-02 7 100860517 100861011 495 + 0.607 1.019 1.636
ENSG00000146828 E035 3.1290038 0.0047421609 4.161408e-03 4.369114e-02 7 100861012 100861137 126 + 0.356 0.758 1.898
ENSG00000146828 E036 35.7111250 0.0003882539 7.863734e-01 9.176781e-01 7 100861138 100861262 125 + 1.553 1.573 0.067
ENSG00000146828 E037 2.5116055 0.0505104918 5.018625e-03 4.976457e-02 7 100861263 100861391 129 + 0.246 0.700 2.401
ENSG00000146828 E038 40.6622527 0.0003609015 4.929156e-01 7.549958e-01 7 100861392 100861519 128 + 1.632 1.607 -0.084
ENSG00000146828 E039 22.7392892 0.0089140082 5.581543e-01 7.998378e-01 7 100861520 100861584 65 + 1.348 1.396 0.164
ENSG00000146828 E040 38.3860945 0.0025259161 9.264688e-01 9.779846e-01 7 100861737 100861911 175 + 1.589 1.599 0.037
ENSG00000146828 E041 40.8921629 0.0036599287 4.127261e-01 6.937842e-01 7 100862681 100862827 147 + 1.639 1.604 -0.119
ENSG00000146828 E042 0.3717172 0.1937250652 6.758020e-01   7 100865287 100865359 73 + 0.098 0.168 0.897
ENSG00000146828 E043 1.0893153 0.1720877867 3.622182e-01 6.514086e-01 7 100865360 100865718 359 + 0.402 0.233 -1.103
ENSG00000146828 E044 138.5577088 0.0001654690 1.763716e-06 7.634371e-05 7 100865719 100867010 1292 + 2.196 2.093 -0.344

Help

Please Click HERE to learn more details about the results from DEXseq.