ENSG00000147439

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000276416 ENSG00000147439 No_inf pgKDN_inf BIN3 protein_coding protein_coding 63.05926 49.58646 65.56173 2.324829 3.723177 0.4028367 7.906976 0.000000 14.807005 0.0000000 5.0804133 10.53303815 0.1213500 0.000000 0.239325 0.239325 0.005833325 0.005833325 FALSE TRUE
ENST00000399977 ENSG00000147439 No_inf pgKDN_inf BIN3 protein_coding protein_coding 63.05926 49.58646 65.56173 2.324829 3.723177 0.4028367 4.609632 2.815324 2.747477 1.4778584 1.9521574 -0.03506772 0.0685750 0.054000 0.043875 -0.010125 0.836498322 0.005833325 FALSE TRUE
ENST00000519335 ENSG00000147439 No_inf pgKDN_inf BIN3 protein_coding protein_coding_CDS_not_defined 63.05926 49.58646 65.56173 2.324829 3.723177 0.4028367 8.904120 2.093428 11.791753 2.0934284 0.2952629 2.48818650 0.1311083 0.037175 0.182200 0.145025 0.024216324 0.005833325 FALSE TRUE
ENST00000519513 ENSG00000147439 No_inf pgKDN_inf BIN3 protein_coding protein_coding 63.05926 49.58646 65.56173 2.324829 3.723177 0.4028367 18.884417 20.479305 18.434632 0.9505901 5.4982100 -0.15167004 0.3115667 0.418050 0.273050 -0.145000 0.447930309 0.005833325 FALSE TRUE
ENST00000520292 ENSG00000147439 No_inf pgKDN_inf BIN3 protein_coding protein_coding 63.05926 49.58646 65.56173 2.324829 3.723177 0.4028367 8.449747 13.674003 4.665731 1.5011056 4.6657314 -1.54922641 0.1438667 0.275750 0.063775 -0.211975 0.012945671 0.005833325 FALSE TRUE
ENST00000522268 ENSG00000147439 No_inf pgKDN_inf BIN3 protein_coding protein_coding 63.05926 49.58646 65.56173 2.324829 3.723177 0.4028367 1.677643 0.000000 3.346607 0.0000000 2.0216684 8.39085978 0.0244250 0.000000 0.050350 0.050350 0.507984920 0.005833325   FALSE
ENST00000522687 ENSG00000147439 No_inf pgKDN_inf BIN3 protein_coding nonsense_mediated_decay 63.05926 49.58646 65.56173 2.324829 3.723177 0.4028367 4.442319 1.217542 3.148655 1.2175421 2.0913698 1.36353774 0.0631750 0.026225 0.045225 0.019000 0.825139217 0.005833325 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000147439 E001 0.0000000       8 22620418 22620435 18 -      
ENSG00000147439 E002 0.0000000       8 22620436 22620711 276 -      
ENSG00000147439 E003 0.0000000       8 22620712 22620774 63 -      
ENSG00000147439 E004 59.3464663 0.0002872860 3.582735e-01 6.477314e-01 8 22620775 22621269 495 - 1.794 1.764 -0.102
ENSG00000147439 E005 64.2000818 0.0002717761 8.548840e-03 7.228829e-02 8 22621270 22621530 261 - 1.853 1.764 -0.302
ENSG00000147439 E006 22.0254187 0.0008327019 2.069282e-01 4.905483e-01 8 22621531 22621568 38 - 1.395 1.320 -0.258
ENSG00000147439 E007 1.3594453 0.0263113687 2.421818e-01 5.318923e-01 8 22622541 22622697 157 - 0.277 0.460 1.081
ENSG00000147439 E008 45.4114592 0.0003320391 1.379362e-01 3.952319e-01 8 22623915 22624049 135 - 1.693 1.633 -0.202
ENSG00000147439 E009 17.3375998 0.0008291858 9.449037e-01 9.847981e-01 8 22624222 22624229 8 - 1.259 1.267 0.029
ENSG00000147439 E010 40.2936092 0.0004078206 9.203995e-01 9.752146e-01 8 22624230 22624363 134 - 1.611 1.620 0.028
ENSG00000147439 E011 7.5787109 0.0021229648 2.576995e-04 5.147439e-03 8 22624364 22625046 683 - 0.718 1.090 1.418
ENSG00000147439 E012 6.6405459 0.0656274693 5.599138e-05 1.463100e-03 8 22625047 22625412 366 - 0.509 1.100 2.379
ENSG00000147439 E013 19.5703269 0.0007461396 9.702203e-14 1.445521e-11 8 22625413 22626542 1130 - 0.996 1.512 1.822
ENSG00000147439 E014 2.0880580 0.0275869811 5.621191e-01 8.021210e-01 8 22629704 22629963 260 - 0.444 0.534 0.444
ENSG00000147439 E015 21.6467330 0.0010907822 4.076899e-01 6.901553e-01 8 22629964 22630004 41 - 1.327 1.383 0.192
ENSG00000147439 E016 49.2241829 0.0003143674 1.490994e-02 1.046937e-01 8 22630442 22630578 137 - 1.743 1.647 -0.326
ENSG00000147439 E017 1.3436764 0.0883039839 9.731003e-01 9.950552e-01 8 22634413 22634525 113 - 0.368 0.370 0.011
ENSG00000147439 E018 29.7750136 0.0007573911 5.856266e-02 2.424408e-01 8 22636525 22636586 62 - 1.531 1.433 -0.336
ENSG00000147439 E019 0.3726934 0.0164173916 4.777202e-01   8 22636590 22636921 332 - 0.087 0.187 1.274
ENSG00000147439 E020 24.7502367 0.0005783475 7.357618e-01 8.951832e-01 8 22636922 22636962 41 - 1.418 1.402 -0.054
ENSG00000147439 E021 0.2357071 0.0156247526 3.110815e-01   8 22644588 22644754 167 - 0.160 0.000 -10.075
ENSG00000147439 E022 26.9210331 0.0005131730 3.414992e-01 6.330471e-01 8 22644755 22644803 49 - 1.418 1.474 0.195
ENSG00000147439 E023 0.0000000       8 22644804 22644804 1 -      
ENSG00000147439 E024 20.5481695 0.0006579377 4.751877e-01 7.418095e-01 8 22669044 22669148 105 - 1.309 1.358 0.171

Help

Please Click HERE to learn more details about the results from DEXseq.