ENSG00000147475

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000519638 ENSG00000147475 No_inf pgKDN_inf ERLIN2 protein_coding protein_coding 51.04471 48.42744 55.14063 1.337293 1.485244 0.1872547 15.028448 5.593821 19.3630198 5.593821 2.9355207 1.7895662 0.29042500 0.115450 0.350850 0.23540 1.735605e-02 6.98931e-16 FALSE TRUE
MSTRG.27533.1 ENSG00000147475 No_inf pgKDN_inf ERLIN2 protein_coding   51.04471 48.42744 55.14063 1.337293 1.485244 0.1872547 6.480560 14.423789 0.0000000 5.041205 0.0000000 -10.4952344 0.13397500 0.299250 0.000000 -0.29925 2.924098e-03 6.98931e-16 FALSE TRUE
MSTRG.27533.2 ENSG00000147475 No_inf pgKDN_inf ERLIN2 protein_coding   51.04471 48.42744 55.14063 1.337293 1.485244 0.1872547 4.897476 0.000000 14.6924290 0.000000 2.7045398 10.5218388 0.08910000 0.000000 0.267300 0.26730 6.989310e-16 6.98931e-16 FALSE TRUE
MSTRG.27533.5 ENSG00000147475 No_inf pgKDN_inf ERLIN2 protein_coding   51.04471 48.42744 55.14063 1.337293 1.485244 0.1872547 1.027652 2.837155 0.2458005 1.740162 0.2458005 -3.4764302 0.02046667 0.057000 0.004400 -0.05260 7.458309e-01 6.98931e-16 TRUE TRUE
MSTRG.27533.6 ENSG00000147475 No_inf pgKDN_inf ERLIN2 protein_coding   51.04471 48.42744 55.14063 1.337293 1.485244 0.1872547 17.476846 18.281161 16.5300906 1.306773 1.1760392 -0.1451795 0.34448333 0.379275 0.299175 -0.08010 6.406570e-01 6.98931e-16 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000147475 E001 0.0000000       8 37736596 37736600 5 +      
ENSG00000147475 E002 0.0000000       8 37736601 37736622 22 +      
ENSG00000147475 E003 0.0000000       8 37736623 37736623 1 +      
ENSG00000147475 E004 0.0000000       8 37736624 37736624 1 +      
ENSG00000147475 E005 0.0000000       8 37736625 37736633 9 +      
ENSG00000147475 E006 0.0000000       8 37736634 37736642 9 +      
ENSG00000147475 E007 0.0000000       8 37736643 37736678 36 +      
ENSG00000147475 E008 0.0000000       8 37736681 37736684 4 +      
ENSG00000147475 E009 0.0000000       8 37736685 37736691 7 +      
ENSG00000147475 E010 1.0069252 0.0116534258 1.827363e-02 0.1194195696 8 37736692 37737007 316 + 0.089 0.454 3.025
ENSG00000147475 E011 0.1272623 0.0123337900 4.838750e-01   8 37737008 37737114 107 + 0.000 0.102 8.728
ENSG00000147475 E012 0.2444846 0.0162904371 9.340938e-01   8 37737115 37737262 148 + 0.089 0.102 0.217
ENSG00000147475 E013 1.1169432 0.1301741496 3.223208e-01 0.6153427474 8 37737610 37737907 298 + 0.226 0.412 1.217
ENSG00000147475 E014 17.5977751 0.0009250947 9.775225e-01 0.9966294594 8 37737908 37738029 122 + 1.261 1.277 0.057
ENSG00000147475 E015 25.5101440 0.0087555903 5.624510e-01 0.8023035061 8 37740365 37740446 82 + 1.433 1.412 -0.074
ENSG00000147475 E016 1.4863961 0.0659050970 2.296771e-01 0.5182653045 8 37740447 37740714 268 + 0.281 0.493 1.217
ENSG00000147475 E017 19.2694934 0.0110839223 4.309962e-01 0.7087183512 8 37741772 37741818 47 + 1.327 1.283 -0.150
ENSG00000147475 E018 24.2921099 0.0005670166 1.815370e-02 0.1189963156 8 37744355 37744416 62 + 1.458 1.334 -0.428
ENSG00000147475 E019 35.5877896 0.0004136575 1.881683e-01 0.4664554756 8 37744571 37744696 126 + 1.585 1.538 -0.160
ENSG00000147475 E020 0.6253605 0.1755030072 1.933827e-01 0.4731549860 8 37744697 37745568 872 + 0.089 0.313 2.216
ENSG00000147475 E021 1.9710505 0.0698266690 5.428407e-01 0.7899832208 8 37745569 37746553 985 + 0.413 0.528 0.579
ENSG00000147475 E022 23.5222746 0.0006023875 3.609567e-01 0.6505544202 8 37749559 37749632 74 + 1.407 1.370 -0.128
ENSG00000147475 E023 26.5513919 0.0006233894 8.245219e-04 0.0129122423 8 37749794 37749852 59 + 1.516 1.339 -0.608
ENSG00000147475 E024 2.3607060 0.0058941726 6.705651e-02 0.2610592710 8 37749853 37750163 311 + 0.373 0.646 1.333
ENSG00000147475 E025 37.2927172 0.0052080645 1.190579e-02 0.0901104178 8 37750395 37750486 92 + 1.638 1.514 -0.423
ENSG00000147475 E026 41.1772405 0.0003563419 1.839923e-03 0.0239407528 8 37751626 37751715 90 + 1.681 1.554 -0.432
ENSG00000147475 E027 39.4993966 0.0003850981 2.053215e-01 0.4885863293 8 37753450 37753529 80 + 1.627 1.585 -0.141
ENSG00000147475 E028 101.6669694 0.0001861256 8.396586e-01 0.9425179443 8 37753915 37754311 397 + 2.005 2.018 0.044
ENSG00000147475 E029 218.5830590 0.0001107576 7.130352e-02 0.2705549061 8 37754312 37755179 868 + 2.349 2.333 -0.053
ENSG00000147475 E030 63.5472622 0.0050697562 3.483182e-01 0.6388340520 8 37755180 37755322 143 + 1.822 1.796 -0.088
ENSG00000147475 E031 47.9447677 0.0003094310 2.628153e-01 0.5556083319 8 37755323 37755608 286 + 1.703 1.674 -0.100
ENSG00000147475 E032 729.8533098 0.0016871995 7.338641e-06 0.0002614842 8 37755609 37758422 2814 + 2.827 2.900 0.241

Help

Please Click HERE to learn more details about the results from DEXseq.