ENSG00000147872

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000276914 ENSG00000147872 No_inf pgKDN_inf PLIN2 protein_coding protein_coding 129.8362 193.1287 121.4605 2.108018 2.280513 -0.6690315 113.16158 158.21214 112.887533 1.784035 0.6723112 -0.4869375 0.8874917 0.819525 0.930075 0.11055 4.680362e-05 4.680362e-05 FALSE TRUE
ENST00000464326 ENSG00000147872 No_inf pgKDN_inf PLIN2 protein_coding protein_coding_CDS_not_defined 129.8362 193.1287 121.4605 2.108018 2.280513 -0.6690315 14.16241 32.38393 6.064933 2.978732 2.6589990 -2.4147830 0.0898000 0.167325 0.049175 -0.11815 1.792903e-01 4.680362e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000147872 E001 2.9916102 1.816374e-02 2.075449e-01 4.911153e-01 9 19108375 19108499 125 - 0.461 0.646 0.857
ENSG00000147872 E002 27.7283991 5.569950e-04 3.615301e-12 4.381745e-10 9 19108500 19108747 248 - 1.091 1.558 1.633
ENSG00000147872 E003 423.0100493 7.621830e-05 5.353918e-01 7.851599e-01 9 19115761 19116358 598 - 2.605 2.612 0.025
ENSG00000147872 E004 348.3450992 8.734884e-05 6.103582e-01 8.306662e-01 9 19116359 19116649 291 - 2.521 2.528 0.024
ENSG00000147872 E005 184.8466619 1.076210e-04 5.261589e-01 7.786252e-01 9 19118321 19118455 135 - 2.243 2.256 0.044
ENSG00000147872 E006 200.4464237 2.890556e-04 8.244698e-01 9.362680e-01 9 19119650 19119831 182 - 2.284 2.288 0.014
ENSG00000147872 E007 186.7121123 1.165364e-04 1.253691e-01 3.753349e-01 9 19120880 19121099 220 - 2.277 2.243 -0.115
ENSG00000147872 E008 59.6076982 5.905370e-03 5.983294e-01 8.238858e-01 9 19121100 19121165 66 - 1.782 1.755 -0.090
ENSG00000147872 E009 0.2543986 1.602811e-02 4.695453e-01   9 19123235 19123312 78 - 0.000 0.140 11.415
ENSG00000147872 E010 0.3798680 3.355526e-02 2.463048e-01   9 19123313 19123476 164 - 0.000 0.196 11.735
ENSG00000147872 E011 0.1268540 1.233623e-02 1.000000e+00   9 19123477 19123564 88 - 0.000 0.076 10.497
ENSG00000147872 E012 65.2474441 2.818714e-03 3.171668e-02 1.682675e-01 9 19123565 19123647 83 - 1.860 1.768 -0.311
ENSG00000147872 E013 1.3870480 9.240422e-03 3.232375e-02 1.701991e-01 9 19125506 19125632 127 - 0.119 0.463 2.594
ENSG00000147872 E014 3.2515733 8.021305e-02 1.686914e-01 4.400270e-01 9 19125633 19126113 481 - 0.461 0.682 1.008
ENSG00000147872 E015 112.9846589 1.402910e-04 1.140070e-01 3.555483e-01 9 19126114 19126309 196 - 2.068 2.022 -0.154
ENSG00000147872 E016 0.6185329 2.134175e-01 9.356276e-01 9.815436e-01 9 19126310 19126396 87 - 0.212 0.196 -0.144
ENSG00000147872 E017 50.2378648 6.458157e-03 5.326198e-01 7.830748e-01 9 19126397 19126448 52 - 1.714 1.679 -0.117
ENSG00000147872 E018 34.5098664 2.194749e-02 3.985051e-01 6.823606e-01 9 19127419 19127534 116 - 1.575 1.508 -0.229
ENSG00000147872 E019 0.0000000       9 19129737 19131214 1478 -      
ENSG00000147872 E020 0.0000000       9 19131215 19131271 57 -      
ENSG00000147872 E021 0.1265070 1.232084e-02 1.000000e+00   9 19149110 19149290 181 - 0.000 0.076 10.498

Help

Please Click HERE to learn more details about the results from DEXseq.