ENSG00000148110

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000375344 ENSG00000148110 No_inf pgKDN_inf MFSD14B protein_coding protein_coding 51.56375 35.31087 62.82706 0.9104937 1.000866 0.831095 4.708893 1.8353287 5.896498 1.8353287 4.0101323 1.6784253 0.08780000 0.054625 0.095900 0.041275 0.862650587 0.007753447 FALSE TRUE
MSTRG.29000.1 ENSG00000148110 No_inf pgKDN_inf MFSD14B protein_coding   51.56375 35.31087 62.82706 0.9104937 1.000866 0.831095 32.810907 21.9712879 40.178231 3.0545392 0.8256616 0.8704971 0.63280833 0.616900 0.640075 0.023175 0.979847334 0.007753447 FALSE TRUE
MSTRG.29000.2 ENSG00000148110 No_inf pgKDN_inf MFSD14B protein_coding   51.56375 35.31087 62.82706 0.9104937 1.000866 0.831095 6.051965 0.7896188 6.012522 0.7896188 3.4725408 2.9129836 0.10626667 0.023275 0.094775 0.071500 0.826035081 0.007753447 FALSE TRUE
MSTRG.29000.3 ENSG00000148110 No_inf pgKDN_inf MFSD14B protein_coding   51.56375 35.31087 62.82706 0.9104937 1.000866 0.831095 3.968789 4.1232009 5.544913 2.5428979 3.2014579 0.4265048 0.08085000 0.116250 0.086400 -0.029850 1.000000000 0.007753447 FALSE TRUE
MSTRG.29000.5 ENSG00000148110 No_inf pgKDN_inf MFSD14B protein_coding   51.56375 35.31087 62.82706 0.9104937 1.000866 0.831095 1.393518 4.1805527 0.000000 1.3941314 0.0000000 -8.7109967 0.03999167 0.119975 0.000000 -0.119975 0.007753447 0.007753447 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000148110 E001 0.0000000       9 94374367 94374394 28 +      
ENSG00000148110 E002 0.8314834 0.0223031784 0.166833543 0.43723089 9 94374534 94374557 24 + 0.332 0.118 -1.871
ENSG00000148110 E003 0.9594099 0.0159466151 0.422317079 0.70157828 9 94374558 94374568 11 + 0.332 0.211 -0.872
ENSG00000148110 E004 0.9594099 0.0159466151 0.422317079 0.70157828 9 94374569 94374569 1 + 0.332 0.211 -0.872
ENSG00000148110 E005 1.8177732 0.1929572451 0.841364821 0.94305428 9 94374570 94374576 7 + 0.434 0.459 0.129
ENSG00000148110 E006 17.3618957 0.0224856006 0.953740566 0.98858913 9 94374577 94374927 351 + 1.251 1.261 0.035
ENSG00000148110 E007 16.5403392 0.0073599810 0.054649770 0.23285517 9 94415158 94415253 96 + 1.287 1.141 -0.515
ENSG00000148110 E008 8.4332738 0.0149163690 0.069101745 0.26561087 9 94429189 94429251 63 + 1.031 0.842 -0.712
ENSG00000148110 E009 7.3270547 0.0022817870 0.009917766 0.07982462 9 94438401 94438528 128 + 0.999 0.731 -1.034
ENSG00000148110 E010 26.7057478 0.0005229708 0.031367391 0.16711608 9 94440985 94441099 115 + 1.475 1.361 -0.396
ENSG00000148110 E011 47.6836951 0.0007953435 0.094925568 0.32058332 9 94444964 94445182 219 + 1.702 1.640 -0.211
ENSG00000148110 E012 34.6249321 0.0149090817 0.822479650 0.93557116 9 94446823 94446936 114 + 1.530 1.561 0.107
ENSG00000148110 E013 25.5635098 0.0029515618 0.377369625 0.66435087 9 94451456 94451527 72 + 1.431 1.389 -0.146
ENSG00000148110 E014 28.7415383 0.0004920602 0.544945126 0.79108202 9 94453958 94454070 113 + 1.472 1.451 -0.073
ENSG00000148110 E015 31.3191163 0.0004594057 0.131163726 0.38421740 9 94456240 94456337 98 + 1.461 1.554 0.317
ENSG00000148110 E016 37.3170282 0.0003865688 0.769842682 0.91114100 9 94458322 94458394 73 + 1.563 1.590 0.093
ENSG00000148110 E017 35.5126881 0.0004339152 0.267513353 0.56090134 9 94458395 94458464 70 + 1.570 1.526 -0.149
ENSG00000148110 E018 0.8511183 0.0137038512 0.820178050 0.93469839 9 94458465 94459160 696 + 0.247 0.288 0.298
ENSG00000148110 E019 510.4792321 0.0021250087 0.010542950 0.08316856 9 94459161 94461042 1882 + 2.682 2.724 0.140

Help

Please Click HERE to learn more details about the results from DEXseq.