ENSG00000148180

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373806 ENSG00000148180 No_inf pgKDN_inf GSN protein_coding nonsense_mediated_decay 364.8264 391.5274 349.1225 10.44368 6.04635 -0.1653753 35.50712 64.95815 21.53617 4.319022 8.006343 -1.5923013 0.09526667 0.165600 0.060575 -0.105025 6.256343e-01 1.258585e-26 FALSE TRUE
ENST00000373818 ENSG00000148180 No_inf pgKDN_inf GSN protein_coding protein_coding 364.8264 391.5274 349.1225 10.44368 6.04635 -0.1653753 24.56815 52.43798 11.36500 3.910930 2.653255 -2.2050206 0.06500833 0.134075 0.032475 -0.101600 1.024227e-05 1.258585e-26 FALSE TRUE
ENST00000394353 ENSG00000148180 No_inf pgKDN_inf GSN protein_coding protein_coding 364.8264 391.5274 349.1225 10.44368 6.04635 -0.1653753 22.79483 47.47273 7.72712 14.924335 7.727120 -2.6175342 0.06145833 0.122650 0.023100 -0.099550 5.896566e-02 1.258585e-26 FALSE TRUE
ENST00000432226 ENSG00000148180 No_inf pgKDN_inf GSN protein_coding protein_coding 364.8264 391.5274 349.1225 10.44368 6.04635 -0.1653753 240.33833 180.21784 277.98409 11.171973 5.672465 0.6252323 0.66740000 0.460375 0.796175 0.335800 1.258585e-26 1.258585e-26 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000148180 E001 0.2458395 1.634329e-02 9.100544e-01   9 121207794 121207799 6 + 0.101 0.089 -0.210
ENSG00000148180 E002 0.3726934 1.649344e-02 6.774821e-01   9 121207800 121207897 98 + 0.101 0.163 0.790
ENSG00000148180 E003 1.0800566 1.107373e-02 5.663950e-02 2.375424e-01 9 121209296 121209397 102 + 0.454 0.163 -2.017
ENSG00000148180 E004 0.9625797 1.821154e-02 1.052644e-01 3.393909e-01 9 121210236 121210317 82 + 0.412 0.163 -1.795
ENSG00000148180 E005 0.2536433 1.595548e-02 2.962829e-01   9 121210318 121210329 12 + 0.000 0.163 10.795
ENSG00000148180 E006 0.8711996 1.309026e-02 3.404714e-01 6.320730e-01 9 121210784 121210867 84 + 0.184 0.330 1.112
ENSG00000148180 E007 0.0000000       9 121216029 121216065 37 +      
ENSG00000148180 E008 1.6146961 8.318927e-03 2.577836e-01 5.500331e-01 9 121231165 121231303 139 + 0.312 0.484 0.960
ENSG00000148180 E009 0.1271363 1.230691e-02 6.213247e-01   9 121248276 121248323 48 + 0.000 0.089 9.895
ENSG00000148180 E010 1.9847417 6.955072e-03 2.242193e-01 5.117449e-01 9 121265154 121265297 144 + 0.365 0.544 0.927
ENSG00000148180 E011 0.2533610 1.594880e-02 2.962911e-01   9 121265661 121265754 94 + 0.000 0.163 10.795
ENSG00000148180 E012 0.7331095 5.876256e-02 8.657456e-01 9.537297e-01 9 121268060 121268161 102 + 0.253 0.226 -0.210
ENSG00000148180 E013 0.6154789 1.726750e-02 7.764888e-01 9.141524e-01 9 121268162 121268162 1 + 0.184 0.226 0.375
ENSG00000148180 E014 0.6154789 1.726750e-02 7.764888e-01 9.141524e-01 9 121268163 121268167 5 + 0.184 0.226 0.375
ENSG00000148180 E015 1.2061579 1.039416e-02 1.358142e-01 3.917532e-01 9 121268168 121268219 52 + 0.454 0.226 -1.432
ENSG00000148180 E016 0.0000000       9 121281470 121281471 2 +      
ENSG00000148180 E017 0.0000000       9 121281472 121281562 91 +      
ENSG00000148180 E018 0.0000000       9 121282439 121282550 112 +      
ENSG00000148180 E019 0.0000000       9 121283319 121283392 74 +      
ENSG00000148180 E020 1.6105403 1.332977e-02 2.612006e-01 5.538911e-01 9 121286123 121286185 63 + 0.312 0.484 0.960
ENSG00000148180 E021 2.9469481 4.745767e-03 9.589195e-01 9.903220e-01 9 121286592 121286761 170 + 0.591 0.598 0.031
ENSG00000148180 E022 3.4432179 6.105018e-03 7.149308e-01 8.850940e-01 9 121297766 121297842 77 + 0.619 0.667 0.205
ENSG00000148180 E023 22.9553466 2.522407e-03 4.333085e-15 7.442694e-13 9 121299793 121300005 213 + 0.974 1.549 2.028
ENSG00000148180 E024 7.4099106 1.834810e-03 2.155357e-01 5.013025e-01 9 121300056 121300126 71 + 0.848 0.974 0.476
ENSG00000148180 E025 6.7183037 2.133869e-03 5.720457e-03 5.452936e-02 9 121301924 121301962 39 + 0.694 0.995 1.168
ENSG00000148180 E026 248.1259144 1.428747e-04 1.861101e-01 4.639953e-01 9 121301963 121302149 187 + 2.408 2.382 -0.086
ENSG00000148180 E027 126.3499032 1.316523e-04 6.482634e-04 1.067912e-02 9 121302150 121302167 18 + 2.151 2.059 -0.308
ENSG00000148180 E028 313.9197088 1.222558e-04 4.082083e-02 1.960958e-01 9 121302911 121303065 155 + 2.515 2.479 -0.118
ENSG00000148180 E029 20.0093907 1.997407e-02 1.261530e-03 1.789596e-02 9 121308371 121310683 2313 + 1.135 1.427 1.025
ENSG00000148180 E030 362.7196273 7.868324e-05 2.508311e-02 1.457038e-01 9 121310684 121310845 162 + 2.577 2.542 -0.118
ENSG00000148180 E031 0.8623544 2.000969e-01 9.029579e-01 9.688647e-01 9 121310846 121311470 625 + 0.253 0.281 0.203
ENSG00000148180 E032 2.3486162 7.277087e-03 4.092056e-01 6.913822e-01 9 121311471 121312338 868 + 0.454 0.572 0.568
ENSG00000148180 E033 346.2635684 2.015467e-04 3.879303e-02 1.905232e-01 9 121312339 121312488 150 + 2.557 2.522 -0.116
ENSG00000148180 E034 8.5048822 1.603191e-03 3.396914e-01 6.313677e-01 9 121312489 121313933 1445 + 0.923 1.014 0.340
ENSG00000148180 E035 224.4103658 8.708499e-04 5.225123e-03 5.124147e-02 9 121313934 121314023 90 + 2.385 2.320 -0.218
ENSG00000148180 E036 287.1631368 7.743274e-05 2.030591e-01 4.856517e-01 9 121317086 121317218 133 + 2.470 2.447 -0.076
ENSG00000148180 E037 1.4659086 1.158294e-01 8.536234e-01 9.483222e-01 9 121317219 121317886 668 + 0.411 0.374 -0.209
ENSG00000148180 E038 275.9447681 8.311035e-05 3.237109e-01 6.163604e-01 9 121318406 121318494 89 + 2.450 2.432 -0.060
ENSG00000148180 E039 243.1606632 3.406479e-04 9.021630e-01 9.686671e-01 9 121318665 121318734 70 + 2.384 2.386 0.009
ENSG00000148180 E040 366.0393494 8.614711e-05 6.450088e-01 8.496667e-01 9 121318735 121318880 146 + 2.558 2.565 0.025
ENSG00000148180 E041 340.7021562 8.649372e-05 7.747498e-01 9.134932e-01 9 121321268 121321401 134 + 2.534 2.529 -0.015
ENSG00000148180 E042 270.8116533 7.294474e-05 8.219804e-01 9.354072e-01 9 121324554 121324644 91 + 2.429 2.434 0.014
ENSG00000148180 E043 231.1554155 7.399402e-05 7.449939e-01 8.990737e-01 9 121326512 121326581 70 + 2.367 2.360 -0.021
ENSG00000148180 E044 290.2160377 7.771435e-05 8.682410e-01 9.548296e-01 9 121326582 121326682 101 + 2.463 2.460 -0.010
ENSG00000148180 E045 0.7421119 1.374676e-02 5.211665e-01 7.753053e-01 9 121326683 121326792 110 + 0.184 0.281 0.790
ENSG00000148180 E046 478.8494992 5.666472e-05 7.288702e-01 8.919101e-01 9 121327308 121327482 175 + 2.676 2.681 0.016
ENSG00000148180 E047 0.6179297 1.569318e-02 7.771220e-01 9.143988e-01 9 121328853 121328890 38 + 0.184 0.226 0.375
ENSG00000148180 E048 399.7489749 7.863043e-05 2.156030e-01 5.014157e-01 9 121328891 121329015 125 + 2.590 2.609 0.063
ENSG00000148180 E049 2.2287931 3.321056e-02 2.962428e-01 5.893040e-01 9 121329016 121329237 222 + 0.412 0.572 0.790
ENSG00000148180 E050 305.9890633 6.962090e-05 3.450465e-01 6.360563e-01 9 121329238 121329315 78 + 2.475 2.492 0.055
ENSG00000148180 E051 317.7522985 6.927636e-05 1.377478e-01 3.950394e-01 9 121331388 121331448 61 + 2.487 2.512 0.085
ENSG00000148180 E052 3.1212922 5.657555e-03 2.296357e-02 1.382119e-01 9 121331449 121331890 442 + 0.412 0.726 1.453
ENSG00000148180 E053 789.8177496 4.505410e-05 5.136241e-05 1.361683e-03 9 121332434 121332843 410 + 2.871 2.914 0.142

Help

Please Click HERE to learn more details about the results from DEXseq.