ENSG00000148248

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000371989 ENSG00000148248 No_inf pgKDN_inf SURF4 protein_coding protein_coding 121.0185 63.35401 140.2785 0.5841852 1.212763 1.146661 115.845837 54.95765 138.4724573 2.670339 1.1514777 1.333049 0.94060000 0.867925 0.98715 0.119225 6.304949e-05 6.304949e-05 FALSE TRUE
ENST00000545297 ENSG00000148248 No_inf pgKDN_inf SURF4 protein_coding protein_coding 121.0185 63.35401 140.2785 0.5841852 1.212763 1.146661 2.553913 4.91342 0.5819952 2.826228 0.5819952 -3.056003 0.03165833 0.077425 0.00405 -0.073375 3.207664e-02 6.304949e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000148248 E001 0.1272623 1.241792e-02 0.253967612   9 133361450 133361463 14 - 0.000 0.130 9.381
ENSG00000148248 E002 724.2173304 6.710046e-04 0.002477634 0.02990125 9 133361464 133362867 1404 - 2.825 2.864 0.132
ENSG00000148248 E003 383.6355330 6.024839e-05 0.168668315 0.43999792 9 133362868 133363452 585 - 2.569 2.554 -0.051
ENSG00000148248 E004 65.3964893 2.744225e-03 0.680403892 0.86812180 9 133363453 133363475 23 - 1.805 1.793 -0.043
ENSG00000148248 E005 95.4413265 1.623603e-04 0.287667300 0.58117501 9 133363476 133363554 79 - 1.973 1.944 -0.098
ENSG00000148248 E006 150.8711444 1.264586e-04 0.144588652 0.40480707 9 133363555 133363759 205 - 2.171 2.139 -0.107
ENSG00000148248 E007 1.9897405 1.683978e-01 0.027579346 0.15489213 9 133363795 133363892 98 - 0.269 0.685 2.159
ENSG00000148248 E008 68.6353112 2.255084e-04 0.419565120 0.69911223 9 133364840 133364914 75 - 1.830 1.805 -0.087
ENSG00000148248 E009 53.6523597 2.713003e-04 0.496576491 0.75755987 9 133364915 133364968 54 - 1.725 1.700 -0.082
ENSG00000148248 E010 59.8617868 2.783975e-04 0.122918383 0.37108760 9 133364969 133365026 58 - 1.783 1.724 -0.198
ENSG00000148248 E011 48.8243406 2.827762e-04 0.404009711 0.68683561 9 133365985 133366028 44 - 1.661 1.703 0.143
ENSG00000148248 E012 0.1176306 1.177166e-02 1.000000000   9 133366029 133366077 49 - 0.069 0.000 -10.810
ENSG00000148248 E013 54.3306446 2.670169e-04 0.870980799 0.95561692 9 133366599 133366675 77 - 1.718 1.730 0.041
ENSG00000148248 E014 85.6860697 1.833590e-04 0.472875777 0.74004243 9 133367259 133367445 187 - 1.923 1.904 -0.065
ENSG00000148248 E015 1.9930244 9.972462e-02 0.004199355 0.04395265 9 133367446 133367543 98 - 0.227 0.715 2.607
ENSG00000148248 E016 0.7343993 1.436299e-02 0.403600437 0.68653805 9 133375239 133375388 150 - 0.181 0.311 1.022
ENSG00000148248 E017 48.6301422 2.869332e-04 0.132618576 0.38654617 9 133375922 133376166 245 - 1.696 1.632 -0.216

Help

Please Click HERE to learn more details about the results from DEXseq.