ENSG00000148339

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373068 ENSG00000148339 No_inf pgKDN_inf SLC25A25 protein_coding protein_coding 9.174349 7.839402 9.938898 0.3902562 0.5611849 0.341954 7.2610505 3.3808112 9.1866853 0.1652249 0.2678311 1.4394835 0.76833333 0.431450 0.92880 0.497350 2.869233e-06 2.869233e-06 FALSE TRUE
ENST00000445012 ENSG00000148339 No_inf pgKDN_inf SLC25A25 protein_coding retained_intron 9.174349 7.839402 9.938898 0.3902562 0.5611849 0.341954 0.5809064 0.7775062 0.6891456 0.3231541 0.2701575 -0.1716984 0.06261667 0.094875 0.06525 -0.029625 9.370223e-01 2.869233e-06 FALSE FALSE
ENST00000466983 ENSG00000148339 No_inf pgKDN_inf SLC25A25 protein_coding protein_coding 9.174349 7.839402 9.938898 0.3902562 0.5611849 0.341954 0.7481140 2.2443421 0.0000000 0.7821410 0.0000000 -7.8165627 0.09089167 0.272675 0.00000 -0.272675 2.159655e-02 2.869233e-06 FALSE FALSE
MSTRG.29348.3 ENSG00000148339 No_inf pgKDN_inf SLC25A25 protein_coding   9.174349 7.839402 9.938898 0.3902562 0.5611849 0.341954 0.2999880 0.8999639 0.0000000 0.8999639 0.0000000 -6.5077374 0.04460833 0.133825 0.00000 -0.133825 8.445594e-01 2.869233e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000148339 E001 0.4799735 0.0203803006 0.474044752   9 128068201 128068231 31 + 0.213 0.109 -1.151
ENSG00000148339 E002 0.4799735 0.0203803006 0.474044752   9 128068232 128068236 5 + 0.213 0.109 -1.151
ENSG00000148339 E003 9.0718602 0.0016674421 0.079151439 0.28848180 9 128068237 128068580 344 + 1.062 0.909 -0.566
ENSG00000148339 E004 0.0000000       9 128091464 128091585 122 +      
ENSG00000148339 E005 0.3804973 0.0158995389 0.059554245   9 128091586 128092089 504 + 0.000 0.268 12.983
ENSG00000148339 E006 0.0000000       9 128094319 128094438 120 +      
ENSG00000148339 E007 0.3801504 0.0196540011 0.060134363   9 128098304 128098536 233 + 0.000 0.268 12.974
ENSG00000148339 E008 0.0000000       9 128098537 128098541 5 +      
ENSG00000148339 E009 0.0000000       9 128098542 128098725 184 +      
ENSG00000148339 E010 0.2435110 0.0162661973 0.827513710   9 128099072 128099274 203 + 0.083 0.109 0.434
ENSG00000148339 E011 0.0000000       9 128099275 128099385 111 +      
ENSG00000148339 E012 1.2417854 0.0470192316 0.102257874 0.33419234 9 128100867 128101095 229 + 0.213 0.476 1.656
ENSG00000148339 E013 6.6942514 0.0021307448 0.853862715 0.94841886 9 128101096 128101222 127 + 0.889 0.878 -0.043
ENSG00000148339 E014 4.9746446 0.0033206076 0.602742050 0.82663606 9 128101309 128101396 88 + 0.797 0.744 -0.210
ENSG00000148339 E015 0.0000000       9 128101397 128101555 159 +      
ENSG00000148339 E016 0.0000000       9 128102080 128102115 36 +      
ENSG00000148339 E017 6.3120150 0.0292662103 0.566368050 0.80469535 9 128102370 128102481 112 + 0.889 0.825 -0.244
ENSG00000148339 E018 4.6244124 0.0774379486 0.721757168 0.88804040 9 128103681 128103721 41 + 0.767 0.722 -0.184
ENSG00000148339 E019 6.5467505 0.0025176542 0.234294883 0.52331388 9 128103722 128103839 118 + 0.923 0.807 -0.447
ENSG00000148339 E020 6.6391045 0.0024650564 0.062185031 0.25040223 9 128105729 128105881 153 + 0.954 0.766 -0.727
ENSG00000148339 E021 7.0093456 0.0022785470 0.105157150 0.33912888 9 128106150 128106257 108 + 0.964 0.807 -0.604
ENSG00000148339 E022 9.7227893 0.0186078080 0.798765933 0.92437811 9 128106353 128106520 168 + 1.037 1.017 -0.076
ENSG00000148339 E023 0.8710734 0.0138538106 0.131964126 0.38543477 9 128106521 128107028 508 + 0.153 0.384 1.756
ENSG00000148339 E024 9.4979259 0.0015721646 0.918374596 0.97439961 9 128107029 128107179 151 + 1.011 1.028 0.062
ENSG00000148339 E025 0.7609946 0.0137083875 0.003529316 0.03893436 9 128107180 128107259 80 + 0.000 0.432 13.851
ENSG00000148339 E026 63.2842750 0.0002958024 0.012577861 0.09321453 9 128107260 128109245 1986 + 1.769 1.848 0.267

Help

Please Click HERE to learn more details about the results from DEXseq.